AMPA depotentiates synaptosomes. by Amadou T. Corera (372197)

“…<p>A, Synaptosomes were either left untreated (0 and 60 min. time points) or treated with AMPA (100 µM) for the indicated times. …”

Metnase regulates gene expression in colon CSCs. by Panagiotis Apostolou (645219)

“…The assays were performed in triplicate and a p-value <0.05 was considered significant. In the control sample the average value is 1.00 indicating that there is no change in gene expression. …”

Partial dependence curves showing how the prediction of the model is globally influenced by each of the features. by Evan J. Tsiklidis (9652615)

“…<p>Pulse rate and systolic blood pressure display threshold behavior, where the probability of survival can decrease at HR > 100 beats / min and SBP < 110mmHg [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0242166#pone.0242166.ref030" target="_blank">30</a>].…”

Oligodendrocyte depletion with Diphtheria Toxin in MOGi-Cre/iDTR mice. by Aniket Ghosh (212168)

“…After 30 days, the level of demyelination was assessed by LFB-PAS staining, and the number of mature oligodendrocytes, by NogoA staining. A decrease of myelination and of mature oligodendrocyte number was observed in MOGi-Cre/iDTR mice treated with DT (left panel), compared to DT-treated MOGi-Cre animals as control (middle panel) and MOGi-Cre/iDTR animals treated with PBS (right panel). …”

Q index and reachability across thresholds. by Kathleen M. Gates (539016)

“…., reachability) and visual depiction (grey, dotted lines) of approach for defining the point at which reachability begins to decrease (middle panel); Q values (bottom panel) up until drop in reachability (denoted with a red circle in the middle panel). …”

Visualizations into biochemical pathways. by Rønnaug Solberg (252034)

“…<i>b) Effect of different resuscitation protocols on these intermediates</i>. Reoxygenation with 100% oxygen for either duration (g2/3) resulted in a significant delay in the decrease in fumarate, succinate and α-ketoglutarate compared to normoxic resuscitation (g1). …”

Mode and mechanism of OGDHC inhibition. by Moustafa Elkalaf (441286)

“…<p><b>A.</b> TPMP causes mixed inhibition of OGDHC. Increasing the concentration of TPMP caused a decrease in the Vmax and an increase in Km. …”

Lingual echolocators modify the intensity of their emissions according to the environmental complexity and the stage of target approach. by Yossi Yovel (43448)

“…<p>(A) Examples of six trials, showing that emission intensity gradually decreases with time along the approach. …”

Binding of <i>Sp</i> CBPs to insoluble polymeric substrates. by Pallinti Purushotham (166740)

“…(A and B) The amount of bound protein was calculated as the difference in protein concentration before and after incubation with the insoluble substrates, (C and D) Decrease in free protein concentration after binding to α- and β-chitin was determined at different time points till 24 h. …”

Bone marrow tissue of mice fed with diets containing GM corn and parental corn. by Yan Song (119387)

“…<p>Photomicrographs of histomorphological examination (100×) of bone marrow in female BALB/c mice in negative control group(A), non-genetically modified parental corn group(B), genetically modified corn group(C), and positive control group(D). …”

Analysis of the relative expression of the PTEN pathway genes. by Edurne Novella-Maestre (746958)

“…<p>(A) fold change of the <i>PTEN</i> gene. Significant differences were obtained when ∆Ct were analyzed and showed the PTEN inhibition produced by bpv(pic) at 100 μM in fresh (G1 <i>vs</i>. …”

Iron regulation of transferrin receptor, ferroportin and ferritin is intact in SK-Mel-5 cells. by Sarah Straud (245572)

“…<p>Treatment of HeLa or SK-Mel-5 cells with 100 µM DFO for 24 hrs resulted in increased expression of the transferrin receptor in both cell lines, and a decrease in ferroportin and ferritin in SK-Mel-5 cells. …”

Lucanthone promotes APE1 cleavage in presence of protease inhibitor. by Mamta D. Naidu (205011)

“…An arrow indicates the corresponding increase in APE1 25 kDa fragment in last two lanes with a decrease in 35.5 kDa APE1 protein.</p>…”

Validation of target gene knockdown at mRNA and protein levels. by Rajshekhar Y. Gaji (417441)

“…<p>A. The percent decrease in mRNA levels of target genes transfected with gene-specific siRNA were determined using q-RT PCR 72 h post-transfection. …”

Immmocytochemistry of DMT1−IRE, DMT1+IRE, Fpn1 and TfR1 proteins in cortical neurons. by Fang Du (232423)

“…<p>Cells were treated with L-DOPA (0, 1, 5, 10, 100, 200 µM) in DMEM+5%FBS for 16 hours and then immunostained for DMT1−IRE (A), DMT1+IRE (B), Fpn1 (C) or TfR1 (D) antibodies. …”

Fitness and distribution of cell types. by Joshua R. Christie (725052)

“…The decrease in heteroplasmy in <i>B</i>₁<i>B</i>₂ cells between generations 0–100 is an artifact of introducing <i>U</i>₁ at a frequency of 0.01 (the influx of <i>U</i>₁ gametes homoplasmic for the wild type haplotype converts some heteroplasmic <i>B</i>₁ and <i>B</i>₂ gametes into homoplasmic gametes, which increases the proportion of homoplasmic <i>B</i>₁<i>B</i>₂ cells). …”

TSS-targeted siRNA abolishes the heparanase expression in cancer cells. by Guosong Jiang (182435)

“…The symbols (# and Δ) indicate a significant decrease from untransfected control (mock) and a significant increase from pGL3/Basic, respectively.…”

Met-depleted mosquitoes exhibit metabolic defects. by Yuan Hou (767606)

“…<p>(A) A decrease in the glycogen levels was observed in Met-depleted adult female mosquitoes, as measured by colorimetry (<i>left</i>) and PAS staining (<i>right</i>). …”

Fis binding site modifications, Langevin dynamics simulations of DNA breathing, and EMSA experiments, the first set. by Kristy Nowak-Lovato (101951)

“…<p>(A) Langevin dynamics simulations demonstrating suppressed local DNA breathing dynamics in the FIS1S sequence (compare to FIS1 in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002881#pcbi-1002881-g002" target="_blank">Figure 2</a>). …”

Systematic review of evidence for the impact and effectiveness of the 1-3-7 strategy for malaria elimination by Richard J. Maude (9416228)

“…</p><h2>Conclusion </h2><p dir="ltr">Overall, the 1-3-7 approach was effectively implemented with a concomitant decrease in cases in malaria elimination settings, however, it was not possible to quantify impact as it was not implemented in isolation. …”