datasheet1_Hepatic Cytochrome P450 Abundance and Activity in the Developing and Adult Göttingen Minipig: Pivotal Data for PBPK Modeling.docx by Laura Buyssens (10651334)

“…In the adult samples, sex-related differences were detected for CYP1A1, CYP1A2, CYP2A19, CYP2E1_2, CYP3A22, CYP4V2_2a and CYP4V2_2b with higher values in female compared to male Göttingen Minipigs. …”

DataSheet4_A new perspective on selenium’s impact on renal function: European population-based analysis of plasma proteome-mediated Mendelian randomization study.pdf by Shaojie Fu (9658334)

“…</p>Methods<p>Utilizing two-sample two-step mediating mendelian randomization (MR) methodology to investigate the genetically causal relationship between selenium level and renal function as well as the role of the plasma proteome in mediating them. …”

H3 K36 Methylation Helps Determine the Timing of Cdc45 Association with Replication Origins by Fiona Pryde (263331)

“…This causes a delay in Cdc45 binding to origins and renders the dynamics of this interaction insensitive to the state of histone acetylation of the surrounding chromosomal region. Furthermore, a decrease in H3 K36me3 and a concomitant increase in H3 K36me1 around the time of Cdc45 binding to replication origins suggests opposing functions for these two methylation states. …”

Impact of geographic accessibility on utilization of the annual health check-ups by income level in Japan: A multilevel analysis by Misuzu Fujita (747794)

“…Both low density and low income were associated with decreased utilization of the health check-ups. Furthermore, a linear relationship was observed between the density of facilities and utilization of the health check-ups in all income groups and its slope was significantly steeper among subjects with an equivalent income of 0.00 yen than among those with equivalent income of 1.01–2.00 million yen (p = 0.028) or 2.01 million yen or more (p = 0.040). …”

AMBRA1 regulates mitophagy by interacting with ATAD3A and promoting PINK1 stability by Martina Di Rienzo (3901312)

“…<p>PINK1 accumulation at the outer mitochondrial membrane (OMM) is a key event required to signal depolarized mitochondria to the autophagy machinery. How this early step is, in turn, modulated by autophagy proteins remains less characterized. …”

SCA of a high-conductance channel. by Melisa Gualdron-López (172625)

“…(<b>E</b>) Current traces of a single channel in response to a low-speed linear increase (upper trace) or decrease (lower trace) of the holding potential. The bath solution contained 1.0 M NH₄Cl, 20 mM Tris-Cl, pH 7.8, and 2 mM DTT at both sides of the membrane. …”

Determination of pediatric asthma severity using retrospective electronic health record prescription data: an analysis before and after the 2020 national asthma education and preve... by Jinqian Pan (21473864)

“…</p> <p>This retrospective analysis included patients ages 2 – 18 years of age from a large, multi-center healthcare provider. …”

DataSheet1_A new perspective on selenium’s impact on renal function: European population-based analysis of plasma proteome-mediated Mendelian randomization study.pdf by Shaojie Fu (9658334)

“…</p>Methods<p>Utilizing two-sample two-step mediating mendelian randomization (MR) methodology to investigate the genetically causal relationship between selenium level and renal function as well as the role of the plasma proteome in mediating them. …”

DataSheet3_A new perspective on selenium’s impact on renal function: European population-based analysis of plasma proteome-mediated Mendelian randomization study.pdf by Shaojie Fu (9658334)

“…</p>Methods<p>Utilizing two-sample two-step mediating mendelian randomization (MR) methodology to investigate the genetically causal relationship between selenium level and renal function as well as the role of the plasma proteome in mediating them. …”

Ethyl pyruvate inhibits oxidation of LDL in vitro and attenuates oxLDL toxicity in EA.hy926 cells by Christine Rossmann (4350973)

“…</p><p>Results</p><p>Oxidation of nLDL using Cu²⁺ ions was remarkably inhibited by EP in a concentration-dependent manner, reflected by decreased levels of LPO, MDA, REM, oxidation-specific epitopes, and diminished cytotoxicity of the obtained oxLDLs in EA.hy926 cells. …”

Table1_A new perspective on selenium’s impact on renal function: European population-based analysis of plasma proteome-mediated Mendelian randomization study.xlsx by Shaojie Fu (9658334)

“…</p>Methods<p>Utilizing two-sample two-step mediating mendelian randomization (MR) methodology to investigate the genetically causal relationship between selenium level and renal function as well as the role of the plasma proteome in mediating them. …”

Sequential extraction of DNA and proteins from AUP samples. by Yanbao Yu (387270)

“…The aggregate in sample #134 released DNA in a decreasing size range with each incubation step. DNase I can cleave nucleic acids to nucleosome monomers (~ 0.2 kbp). …”

Image_3_Compound small peptide of Chinese medicine alleviates cyclophosphamide induced immunosuppression in mice by Th17/Treg and jejunum intestinal flora.JPEG by Yuqing Cui (1529068)

“…<p>The aim of this study was to explore the efficacy of Compound small peptide of Chinese medicine (CSPCM) on cyclophosphamide (CTX) induced immunosuppression in mice. The 100 male Kunming mice were divided into 5 groups: group A (control group), group B (model group), group C (100 mg/kg.bw CSPCM), group D (200 mg/kg.bw CSPCM) and group E (400 mg/kg.bw CSPCM). …”

Effects of the mutant L29Q cTnC and SD cTnI determined by Molecular Dynamics simulations. by Alison Y. Li (486146)

“…The Ca²⁺ ion bound in site II is shown as a black sphere. (C) shows the largest movement caused by the L29Q mutation in the presence of the pseudo-phosphorylated cTnI, which is the re-orientation of helix A and helix B of cNTnC accompanied by a decrease of interhelical angle of 13°.…”

Small-diameter sensory neurons from mutant mice have relatively few deficits in chemical activation. by Katherine J. Zappia (3178827)

“…<p>(<b>A</b>) Calcium imaging of small-diameter DRG neurons revealed no difference in the percentage of neurons responding to the 100 μM of the TRPA1 agonist, cinnamaldehyde, when comparing control and mutant neurons. …”

Image_1_Compound small peptide of Chinese medicine alleviates cyclophosphamide induced immunosuppression in mice by Th17/Treg and jejunum intestinal flora.JPEG by Yuqing Cui (1529068)

“…<p>The aim of this study was to explore the efficacy of Compound small peptide of Chinese medicine (CSPCM) on cyclophosphamide (CTX) induced immunosuppression in mice. The 100 male Kunming mice were divided into 5 groups: group A (control group), group B (model group), group C (100 mg/kg.bw CSPCM), group D (200 mg/kg.bw CSPCM) and group E (400 mg/kg.bw CSPCM). …”

Relationship between functional disability and costs one and two years post stroke by Ingrid Lekander (3910180)

“…</p><p>Method</p><p>Resource use during first and second year following a stroke was estimated based on a research database containing linked data from several registries. …”

GPR39-expressing cells. by Fanning Zeng (124301)

“…Shown are ratiometric images of Ca²⁺ signals before and after 100 µM Zn²⁺ challenge. [Ca²⁺]<i>_i</i> is indicated on a rainbow scale with blue representing low [Ca²⁺]<i>_i</i> and orange/red high [Ca²⁺]<i>_i</i>. …”

Electrophoretic mobility shift assay showing the interaction of wild type TsTBP1 with Ts2-CysPrx TATA-box probe. by Oscar Rodríguez-Lima (821378)

“…B) The densitometric analysis shows a decrease on the intensity of shifted bands in homologous and heterologous competition. …”

Electrophoretic mobility shift assay showing the interaction of wild type TsTBP1 pAT5 TATA-box probe. by Oscar Rodríguez-Lima (821378)

“…B) Densitometric analysis shows a decrease on the intensity of shifted bands in homologous and heterologous competition. …”