At clinically relevant concentrations the anaesthetic/amnesic thiopental but not the anticonvulsant phenobarbital interferes with hippocampal sharp wave-ripple complexes-2 by Costas Papatheodoropoulos (78587)

“…The cross-correlation plot from another slice (b) illustrates the large decrease of function value during drug application at 100 μM. …”

Data_Sheet_1_Ambient Temperature Is Correlated With the Severity of Neonatal Hypoxic-Ischemic Brain Injury via Microglial Accumulation in Mice.PDF by Rika Zen (12509164)

“…The size of the striatum and hippocampus and the volume reduction rate of the hemisphere in the section containing them on the ischemic side were evaluated using microtubule associated protein 2 (MAP2) immunostaining. The accumulation of Iba1-positive cells was investigated to assess inflammation. …”

Proposed epigenetic regulatory mechanism during the somatic embryogenesis of <i>Coffea canephora</i>. by Geovanny I. Nic-Can (448043)

“…Finally, during the late developmental embryo stage, T, an increase of H3K9me2 promotes the transcriptional repression of <i>WOX4</i> and H3K27me3 again starts accumulating on <i>LEC1</i> and the expression of <i>BBM1</i> decreases. …”

Pioglitazone Improves Fat Distribution, the Adipokine Profile and Hepatic Insulin Sensitivity in Non-Diabetic End-Stage Renal Disease Subjects on Maintenance Dialysis: A Randomized... by Anne Zanchi (645982)

“…</p><p>Methods</p><p>At the end of each phase, body composition (anthropometric measurements, dual energy X-ray absorptometry (DEXA), abdominal CT), hepatic and muscle insulin sensitivity (2-step hyperinsulinemic euglycemic clamp with 2H2-glucose) were measured and fasting blood adipokines and cardiometabolic risk markers were monitored.…”

Image_1_DALY trend and predictive analysis of COPD in China and its provinces: Findings from the global burden of disease study.tif by Mimi Zhai (13232313)

“…The ASR of DALY was 1445.53 per 100,000 people in 2017 and demonstrated a significant decrease. …”

Image_2_DALY trend and predictive analysis of COPD in China and its provinces: Findings from the global burden of disease study.tif by Mimi Zhai (13232313)

“…The ASR of DALY was 1445.53 per 100,000 people in 2017 and demonstrated a significant decrease. …”

Effect of LYZL6 antiserum on sperm-egg binding and fusion. by Peng Huang (105814)

“…<p>A) The mean number (± SD) of spermatozoa bound per egg did not differ significantly between the control and the antiserum-treated groups (control: 29 ± 3.07; anti-LYZL6 serum: 1: 100, 23 ± 2.48; 1: 200, 26 ± 3.20; 1: 400, 28 ± 3.56; 1: 800, 27 ± 2.34; 1: 1600, 30 ± 3.85). …”

Activation of AMPK prevented drug-induced hepatocellular injury and hepatocyte depolarization. by Sun Woo Sophie Kang (3280878)

“…After hepatocytes were treated with various concentrations of acetaminophen (APAP) or diclofenac (Diclo), dose-viability response curves were obtained for (<b>A</b>) acetaminophen (1–20mM, 24hr) in rat hepatocytes, (<b>B</b>) diclofenac (50–800μM, 24hr) in rat hepatocytes, (<b>C</b>) acetaminophen (1–50mM, 24hr) in human hepatocytes, and (<b>D</b>) diclofenac (100–3000μM, 24hr) in human hepatocytes. …”

Calcium partition in Minas Padrão cheese and its bioaccessibility during ripening time by João Pablo Fortes PEREIRA (6072374)

“…The mean values found for total calcium content were (549 mg⋅100 g-1 – A and 644 mg⋅100 g-1 – B). …”

Calcium partition in Minas Padrão cheese and its bioaccessibility during ripening time by João Pablo Fortes PEREIRA (6072374)

“…The mean values found for total calcium content were (549 mg⋅100 g-1 – A and 644 mg⋅100 g-1 – B). …”

Semiparametric pairwise model outperforms other models. by Jan Humplik (4445659)

“…<b>D)</b> Average (across neurons) error rate decrease achieved by using a semiparametric pairwise model instead of a K-pairwise model for subpopulations of various sizes. …”

Superoxide flashes induce mitochondrial depolarizations, independently from the activity of the permeability transition pore. by Sandrine Pouvreau (240917)

“…Note the spatial and temporal colocalization of the increase in RPmt and decrease in TMRM fluorescence. <b>C</b> Total area of mitochondria presenting a flash or a depolarization per 1000 µm² cell per 100 s, in 5 cells under control conditions and after 20 min of treatment with 15 mM tiron (*: p<0.05 for control vs tiron, paired Wilcoxon Signed Rank test). …”

OSM activates ERK-1/2, SAPK/JNK-1/2 MAP kinases, the PI3-kinase Akt and STAT1/3 in HCT116 cells and STAT3 activation is dependent of the LIFR. by Florian Beigel (174724)

“…<p>(A) Stimulation with OSM (100 ng/mL) resulted in increased phosphorylation of ERK-1/2, SAPK/JNK-1/2 kinases and induced PI3 kinase-dependent Akt phosphorylation. …”

Table 1_The impact of percutaneous endoscopic gastrostomy on nutritional status and survival in cervical esophageal cancer patients undergoing chemoradiotherapy.docx by Zijun Wen (21596450)

“…The 2, 3, and 4 year OS rates for the PEG group were 81.9% (95% confidence interval [CI]: 63.2–100%), 54.3% (95% CI: 25.5–83.1%), and 32.6% (95% CI: 0.0–63.6%), respectively, while the Non-PEG group had 2, 3, and 4 year OS rates of 100% (95% CI: 83.0–100%), 82.1% (95% CI: 59.2–100%), and 49.2% (95% CI: 11.4–87.0%), respectively. …”

CXCR4 inhibition reduces inflammatory cell infiltration, angiogenesis and inflammatory marker expression in the imiquimod-induced skin inflammation. by Silvana Zgraggen (546104)

“…(M–P) Real-time RT-PCR analyses of RNA from whole ear skin extracts of imiquimod-inflamed mice showed a significant downregulation of CXCL3 (M), CCL20 (N), S100a7 (O) and S100a8 (P). …”

Data_Sheet_1_Trends in mortality and causes of death among Chinese adolescents aged 10–19 years from 1990 to 2019.ZIP by Jiaxin Zhu (446571)

“…Regarding age, compared with those aged 10–14 years, the mortality rate of adolescents aged 15–19 years had a higher mortality (35.9/100,000 vs. 21.2 in 2019) and a slower decrease rate (percent: −57.6 vs. −63.2). …”

Effects of activators and inhibitors on TcPiezo channels. by Guozhong Huang (673424)

“…Downregulation of <i>TcPiezo2</i> expression (+Tet) showed a significant decrease of lysosomal Ca²⁺ release as in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1013105#ppat.1013105.g004" target="_blank">Fig 4A</a>. …”

Dorsal and chinmo mutually influence each other’s expression, driving tumor growth while inhibiting differentiation. by Caroline Dillard (15381444)

“…Insets show a decrease of elav+ (magenta) cells within the tumor upon chinmo^OE. …”

Reactions of NPY+ and ChAT+ interneurons to QA. by Qiqi Feng (535984)

“…Cont is short for control. Scale bars: A–D, 100 μm; A′–D′, 30 μm; B*, 10 μm.</p>…”

Thermo-economic assessment of forward osmosis as pretreatment to boost the performance and sustainability of multi-effect distillation for seawater desalination by Ortega-Delgado, B.

“…Results show that using FO pretreatment in a 100 m3/d MED plant of 8 effects at 65 °C allows increasing the heating steam temperature up to 100 °C and the number of effects to 16 without increasing the risk of scaling. …”
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