P2rx7 participates in the regulation of the basal BDNF expression in the mouse hippocampus. by Cecilia Csölle (425362)

“…The inhibitory effect of BzATP (100 µM) could be counteracted using CNQX (10 µM), the non-NMDA-type glutamate receptor antagonist, TCN-201 (10 µM), the NMDA-NR1/NR2A glutamate receptor antagonist and RO-256981 (3 µM) the NMDA-NR2B glutamate receptor antagonist but not using MCPG (200 µM), the group I mGluR antagonist. …”

Force types and force screen. by Angelika Manhart (1379565)

“…B: Structure of the force screen: Two filtering steps are followed by a calibration step. …”

Feijoa F3 activates autophagy and inhibits NF-κB activity in HCT15 cells. by Noha Ahmed Nasef (760610)

“…A percentage of greater than 100 shows increased inflammatory response in the presence of the ligand when compared to media (no treatment); and a percentage of less than one suggests a decrease in the inflammatory response in the presence of the ligand when compared to media (no treatment) meaning that a condition has inhibited NF-κB signaling. …”

Table_1_Effects of an In-home Multicomponent Exergame Training on Physical Functions, Cognition, and Brain Volume of Older Adults: A Randomized Controlled Trial.docx by Manuela Adcock (8365122)

“…Two measures of short-term attentional span showed improvements after training in favor of the control group [F₍₁₎ = 4.309, p = 0.038, np2 = 0.03, F₍₁₎ = 8.504, p = 0.004, np2 = 0.04]. …”

Clinical Response and Remission Results for the 36-Week Maintenance Period. by Satish Keshav (65388)

“…a<p>Sustained response was defined as a decrease in CDAI score from baseline (last non missing value before the first dose in the Induction period) ≥70 at Week 16 and no loss of the response during the 36-week Maintenance period. …”

Connectivity properties of the SOM-VIP motif support the amplification in the interneuron network. by Loreen Hertäg (2802439)

“…Recurrence leads to a decrease of the amplification index (right). …”

Microfluidic Pheromone Arena for mate choice assays. by Flora Borne (4683502)

“…The three inlets correspond to the three worm chambers: inlets 1 and 2 connect to the upstream chambers and inlet 3 connects to the downstream chamber. All the chambers have a pillar-array (shown as circles) spaced 100um apart to allow for natural worm movement. …”

The effect of irisin on H/R induced MMP reduction in H9c2 cells. by Yu Tina Zhao (3359159)

“…Exposing H9c2 cells to H/R caused a significant decrease in the ratio of red to green fluorescence intensity, which is a sign of the early stages of cell apoptosis. …”

SINGLE PORT LAPAROSCOPIC CHOLECYSTECTOMY: TECHNICAL ASPECTS AND RESULTS by Murillo de Lima FAVARO (5670416)

“…The mean surgical time was 67.97 min, showing a marked decrease when was reached close to 50 cases and a stabilization after 100 surgeries. …”

Rainfall interception in temperate evergreen broadleaved forest and Japanese cypress plantation with abundant lower-layer vegetation in south-west Japan by Masahiro Takagi (344553)

“…Here, we compared the throughfall and stemflow of each vegetation layer to clarify interception in a naturally regenerated temperate evergreen broadleaved forest (lucidophyllous forest) and a Japanese cypress plantation over a three-year period. …”

Perifosine targets the Aldefluor-positive cell population in breast cancer xenografts. by Hasan Korkaya (159560)

“…In contrast, perifosine treatment alone or in combination with docetaxel produced a 75–90% decrease in the proportion of cancer stem/progenitor cells as assessed by the Aldefluor assay. …”

Turnover of 4MUG substrate detects GBA1 activity in mouse brain lysates in the presence of sodium taurocholate. by Zdenek Berger (440685)

“…When converted to specific activity, similar values are obtained when using 10–60 μg of mouse brain lysates, as expected. A representative experiment is shown. B) Turnover of 4MUG substrate in lysates from mouse brain is mostly due to GBA1 activity when using sodium taurocholate (NaTc). 1 mM CBE and 1 μM isofagomine (Iso) decrease the signal by ~ 80% in the presence of sodium taurocholate (+ NaTc) whereas substantially smaller reduction is seen without sodium taurocholate (- NaTc) in the assay buffer. 10 μg of protein lysate was used in the reaction. …”

3-D MicroCT images of trabecular bone microarchitecture in the distal femora in Control, OVX and OVX+PEMF rats. by Da Jing (404219)

“…The VOI started at a distance of 0.4 mm (25 slices) from the lowest end of the growth plate and extended to the proximal end of the femur with a distance of 1.6 mm (100 slices). …”

Inhibitors of Cl⁻ channels differently affect OGD-induced swelling in HR-and LR-astrocytes. by Jana Benesova (155548)

“…<p>The effect of 100 µM NPPB, a non-specific inhibitor of chloride channels (<b>A</b>), 30 µM Tamoxifen (<b>B</b>) and 30 µM DCPIB (<b>C</b>), inhibitors of volume regulated anion channels. …”

Dasatinib promotes nuclear shuttling of ER in the MCF7-TAMR cells but not the 1%MCF7. by Stephanie K. Guest (2838575)

“…<p>1%MCF7 and MCF7-TAMR cells were treated for 24-hours with 1%FBS, dasatinib (100nM), 4-OHT (10nM), or the combination and stained with ER, pSrc^tyr416 and DAPI; bars indicate 20μm <b>(A)</b>. …”

Inflammation has dual-roles during regeneration. by Suqi Zou (379705)

“…Scale bar: 10 µm (A-C, M-P); 2 µm (D); 30 µm (G), 100 µm (F, I and J).…”

Effects of the MB and its derivatives on cellular oxygen consumption rate (OCR). by Ethan Poteet (125162)

“…(D) Rotenone inhibits complex I causing a decrease in OCR, which was significantly attenuated by the treatment of MB, NR, and TB. * p<0.05 compared to control group.…”

Confocal microscopy study of the binding of Bid and caspase-8 to giant unilamellar vesicles containing cardiolipin. by Olivier Jalmar (283659)

“…The arrows indicate the decrease in GUV fluorescence following the formation of a complex between procaspase-8 and Bid_Alexa488, resulting in a non-fluorescent tBid.…”

Effect of MEHP and PMA on the gene transcription of TSPO, PKCε, PPAR-α, PPAr-β/δ, and PPAR-γ. by Enrico Campioli (336888)

“…Cells were seeded for 24 h before treatment with MEHP (A–C) or PMA (D) and collected after the indicated time points (A) or after 4 days (B–D). qRT-PCR results are normalized to RPS18, expressed in terms of mean and S.E.M. calculated from 3 independent experiments, and presented as fold increase or decrease compared to control. …”

Valproate Administered after Traumatic Brain Injury Provides Neuroprotection and Improves Cognitive Function in Rats by Pramod K. Dash (246530)

“…</p> <h3>Methodology/Principal Findings</h3><p>Using a rodent model of TBI, we tested if post-injury administration of valproate can decrease BBB permeability, reduce neural damage and improve cognitive outcome. …”