The effect of estrogen deprivation and estrogen treatment on the growth of BRCA1 antisense and control cells by Lois A Annab (54446)

“…</p><p>Copyright © This article is a work of the United States Government and as such must remain in the public domain</p> The mean cell number of BRCA1 pooled population antisense infected cells (filled circle) and vector-only infected cells (white circle) deprived of estrogen for up to 20 days after plating 2.5×10 cells per 100-mm dish. …”

HIV-1 and Its gp120 Inhibits the Influenza A(H1N1)pdm09 Life Cycle in an IFITM3-Dependent Fashion by Milene Mesquita (236262)

“…The knowledge that HIV-1 changes the host homeostatic equilibrium, which may favor the patient resistance to some co-pathogens, prompted us to investigate whether HIV-1 infection could influence A(H1N1)pdm09 life cycle <i>in vitro</i>. We show here that exposure of A(H1N1)pdm09-infected epithelial cells to HIV-1 viral particles or its gp120 enhanced by 25% the IFITM3 content, resulting in a decrease in influenza replication. …”

Table_1_Efficacy and Safety of Complementary Therapy With Jing Si Herbal Tea in Patients With Mild-To-Moderate COVID-19: A Prospective Cohort Study.DOCX by Po-Chun Hsieh (10920474)

“…Background<p>Since late 2019, there has been a global COVID-19 pandemic. To preserve medical capacity and decrease adverse health effects, preventing the progression of COVID-19 to severe status is essential. …”

Table1_Safety and efficacy of renal sympathetic denervation: a 9-year long-term follow-up of 24-hour ambulatory blood pressure measurements.docx by Alexander Vogt (375813)

“…Renal function showed a significant but expected age-associated decrease in the eGFR from 87.8 (IQR: 81.0–100.0) to 72.5 (IQR: 55.8–86.8) ml/min/1.73 m² (P < 0.01) in patients with an initial eGFR > 60 ml/min/1.73 m², while a non-significant decrease was observed in patients with an initial eGFR < 60 ml/min/1.73 m² at long-term FU [56.0 (IQR: 40.9–58.4) vs. 39.0 (IQR: 13.5–56.3) ml/min/1.73 m²].…”

Datasheet1_Safety and efficacy of renal sympathetic denervation: a 9-year long-term follow-up of 24-hour ambulatory blood pressure measurements.pdf by Alexander Vogt (375813)

“…Renal function showed a significant but expected age-associated decrease in the eGFR from 87.8 (IQR: 81.0–100.0) to 72.5 (IQR: 55.8–86.8) ml/min/1.73 m² (P < 0.01) in patients with an initial eGFR > 60 ml/min/1.73 m², while a non-significant decrease was observed in patients with an initial eGFR < 60 ml/min/1.73 m² at long-term FU [56.0 (IQR: 40.9–58.4) vs. 39.0 (IQR: 13.5–56.3) ml/min/1.73 m²].…”

Data_Sheet_1_Impact of Coinfection With SARS-CoV-2 and Influenza on Disease Severity: A Systematic Review and Meta-Analysis.docx by Zhou Guan (3723796)

“…However, mortality was found significantly decreased in the studies from China (OR = 0.51, 95%CI: 0.39, 0.68; I² = 26.50%), while significantly increased outside China (OR = 1.56, 95%CI: 1.12, 2.19; I² = 1.00%). …”

Supplementary Figure 1 from Delineating the mTOR Kinase Pathway Using a Dual TORC1/2 Inhibitor, AZD8055, in Multiple Myeloma by Diana Cirstea (48960)

“…Transfected cells (IGF1R knock out cells) were cultured with and without AZD8055 100 nM. IGF1R knockout cells show 39% decrease in viability compared to scramble control and the combination of IGF1R knock out and AZD8055 100 nM show a 78% decrease in viability compared to scramble control. …”

Supplementary Material for: Dose-dependent relationship between iron metabolism and perioperative myocardial injury in cardiac surgery with cardiopulmonary bypass: A retrospective... by Li Q. (2850350)

“…The primary outcome was PMI with a 100x upper reference limit (URL). Results: Of 2420 patients screened,744 eligible patients were enrolled for the final analysis. …”

Table1_A Sediment Magnetic Record in the North Pacific Across the Mid-Pleistocene Transition and its Implication on Asian Dust Evolution.XLSX by Ji Young Shin (9136598)

“…The detrital magnetic component is characterized by high coercivity (>100 mT) and shows a long-term increase in concentration since ∼1 Ma. …”

Image_1_The relationship between central obesity and risk of breast cancer: a dose–response meta-analysis of 7,989,315 women.jpg by Hongyang Chen (410527)

“…Regarding the BC subtype, central obesity is proven to be a risk of ER+ and ER- BCs. The dose–response analysis revealed that when BMI (during premenopausal) exceeded 23.40 kg/m², the risk of BC began to decrease, and WC higher than 83.80 cm or WHR exceeded 0.78 could efficiently increase the BC risk.…”

Table_6_The relationship between central obesity and risk of breast cancer: a dose–response meta-analysis of 7,989,315 women.DOCX by Hongyang Chen (410527)

“…Regarding the BC subtype, central obesity is proven to be a risk of ER+ and ER- BCs. The dose–response analysis revealed that when BMI (during premenopausal) exceeded 23.40 kg/m², the risk of BC began to decrease, and WC higher than 83.80 cm or WHR exceeded 0.78 could efficiently increase the BC risk.…”

Table_1_The relationship between central obesity and risk of breast cancer: a dose–response meta-analysis of 7,989,315 women.DOCX by Hongyang Chen (410527)

“…Regarding the BC subtype, central obesity is proven to be a risk of ER+ and ER- BCs. The dose–response analysis revealed that when BMI (during premenopausal) exceeded 23.40 kg/m², the risk of BC began to decrease, and WC higher than 83.80 cm or WHR exceeded 0.78 could efficiently increase the BC risk.…”

Table_3_The relationship between central obesity and risk of breast cancer: a dose–response meta-analysis of 7,989,315 women.docx by Hongyang Chen (410527)

“…Regarding the BC subtype, central obesity is proven to be a risk of ER+ and ER- BCs. The dose–response analysis revealed that when BMI (during premenopausal) exceeded 23.40 kg/m², the risk of BC began to decrease, and WC higher than 83.80 cm or WHR exceeded 0.78 could efficiently increase the BC risk.…”

Image_2_The relationship between central obesity and risk of breast cancer: a dose–response meta-analysis of 7,989,315 women.jpg by Hongyang Chen (410527)

“…Regarding the BC subtype, central obesity is proven to be a risk of ER+ and ER- BCs. The dose–response analysis revealed that when BMI (during premenopausal) exceeded 23.40 kg/m², the risk of BC began to decrease, and WC higher than 83.80 cm or WHR exceeded 0.78 could efficiently increase the BC risk.…”

Table_4_The relationship between central obesity and risk of breast cancer: a dose–response meta-analysis of 7,989,315 women.DOCX by Hongyang Chen (410527)

“…Regarding the BC subtype, central obesity is proven to be a risk of ER+ and ER- BCs. The dose–response analysis revealed that when BMI (during premenopausal) exceeded 23.40 kg/m², the risk of BC began to decrease, and WC higher than 83.80 cm or WHR exceeded 0.78 could efficiently increase the BC risk.…”

Table_2_The relationship between central obesity and risk of breast cancer: a dose–response meta-analysis of 7,989,315 women.DOCX by Hongyang Chen (410527)

“…Regarding the BC subtype, central obesity is proven to be a risk of ER+ and ER- BCs. The dose–response analysis revealed that when BMI (during premenopausal) exceeded 23.40 kg/m², the risk of BC began to decrease, and WC higher than 83.80 cm or WHR exceeded 0.78 could efficiently increase the BC risk.…”

Table_5_The relationship between central obesity and risk of breast cancer: a dose–response meta-analysis of 7,989,315 women.DOCX by Hongyang Chen (410527)

“…Regarding the BC subtype, central obesity is proven to be a risk of ER+ and ER- BCs. The dose–response analysis revealed that when BMI (during premenopausal) exceeded 23.40 kg/m², the risk of BC began to decrease, and WC higher than 83.80 cm or WHR exceeded 0.78 could efficiently increase the BC risk.…”

Image_1_Dissociable Effects of Reward on P300 and EEG Spectra Under Conditions of High vs. Low Vigilance During a Selective Visual Attention Task.pdf by Jia Liu (41593)

“…To explore the possible differences in the influence of motivation on behavioral performance and neural activity in high and low vigilance levels, we conducted a prolonged 2 h 20 min flanker task and provided monetary rewards during the 20- to 40- and 100- to 120-min intervals of task performance. …”

Image_1_Tra2beta-Dependent Regulation of RIO Kinase 3 Splicing During Rift Valley Fever Virus Infection Underscores the Links Between Alternative Splicing and Innate Antiviral Immu... by Luke Adam White (6744089)

“…Intriguingly, TRA2-β mRNA is also alternatively spliced during RVFV infection, leading to a decrease in cellular TRA2-β protein levels. …”

Supplementary Material for: Waning of SARS-CoV-2 Vaccine-Induced Immune Response over 6 Months in Peritoneal Dialysis Patients and the Role of a Booster Dose in Maintaining Seropos... by Murt A. (9984845)

“…The initial seropositivity rate was 90.9% with inactivated vaccine and 100% with mRNA vaccine. Seropositivity decreased to 44.4% after 6 months, and a booster dose helped in maintaining the 100% of seropositivity (<i>p</i> = 0.005). …”