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step decrease » sizes decrease (Expand Search), teer decrease (Expand Search)
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461
Increased lipid accumulation and decreased klotho expressions in palmitate-treated mouse podocytes.
Published 2021“…Boxes are enlarged images of representative lipid droplets. magnification 20x; scale bar = 50 μm and 100 μm. (c) Western blot showing the decreased expression of klotho and nephrin proteins by palmitate treatment. …”
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Expression of SPDEF in prostate adenocarcinoma cells decreased prostate carcinogenesis in orthotopic model.
Published 2014“…<p>Mouse prostates were harvested 5 weeks after inoculation of control TRAMP C2 adenocarcinoma cells or TRAMP C2 cells with stable expression of SPDEF (SPDEF OE). <b>A</b>. SPDEF decreased the growth of prostate tumors in orthotopic model. …”
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466
LNAME and TEMPOL restored α-actin and decreased MMPs at the BT of ligated animals.
Published 2014“…<p>Smooth muscle α-actin, MMP-2 and MMP-9 proteins were detected by immunofluorescence in sham-operated animals (A, F, K), and in CCA ligated animals given no inhibitors (B, G, L), or treated with LNAME (C, H, M), or TEMPOL (D, I, N). α-actin staining in the media significantly decreased at the BT following ligation (B) compared to sham-operated animals (A), but was restored with either LNAME (C) or TEMPOL (D) treatment. …”
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Decreased myofibroblasts in the peritumoral region and high expression of MMP-7 in Pan02 S.C. tumor of <i>S100a4-Cre; Ext1</i><sup><i>f/f</i></sup> mice.
Published 2023“…<p>(A) Immunostaining of α-smooth muscle actin (αSMA)-positive spindle cells, i.e., myofibroblasts, in the peritumoral region of Pan02 S.C. pancreatic tumors in <i>S100a4-Cre; Ext1</i><sup><i>f/f</i></sup> and control mice (left). …”
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