The effect of PKCλ knock-down on hyperglycemia-induced insulin resistance. by Katherine A. Robinson (645068)

“…</b> cells preincubated in 5 mM glucose (IS) vs. 25 mM glucose+0.6 nM insulin (GI-IR) and then stimulated (the black bars) or not (basal) with acute, 100 nM insulin. Knock-down of PKCλ mRNA decreased the insulin-stimulation of glucose transport by ∼20%, in IS adipocytes, but had no additional effect in GI-IR adipocytes. …”

Agrin loss leads to disassembly of the postsynaptic apparatus. by Melanie A. Samuel (253429)

“…<p>A–B. Triangularis sterni muscle from control (A) and conditional agrin knockout (B) animals 3 months after tamoxifen (TX) administration. …”

Effect of impaired intestinal lipid transport on intestinal epithelial apoptosis. by Jessica A. Dominguez (299535)

“…<p>Intestinal epithelial apoptosis was evaluated by active caspase-3 staining (A) and H&E staining (B) in 100 crypts. Control mice subjected to <i>P. aeruginosa</i> pneumonia exhibited increased intestinal apoptosis by both methods. …”

Simultaneous determination of invasion and cytotoxicity. by Nikki A. Evensen (495977)

“…<p>HT1080 cells expressing GFP were assembled in the 3-D invasion assay in the presence of (A) DMSO, (B) anti-β1 integrin antibody (5 μg/ml), (C) staurosporine (STS) (500 nM), or (D) paclitaxel (Taxol, 1 μM) for 18 hours. …”

Evaluation of serum creatinine (sCr in A) and plasma NGAL (pNGAL in B) in the first 4 consecutive days after KT in non-DGF patients (n = 36). by Vincenzo Cantaluppi (92814)

“…<p>NGAL significantly decreased starting from day 2 to day 4 after KT reaching a value near to normal levels (100 ng/ml). …”

Image1_Pleiotropic Effects of Simvastatin and Losartan in Preclinical Models of Post-Traumatic Elbow Contracture.TIF by Michael A. David (12111687)

Image3_Pleiotropic Effects of Simvastatin and Losartan in Preclinical Models of Post-Traumatic Elbow Contracture.TIF by Michael A. David (12111687)

DataSheet1_Pleiotropic Effects of Simvastatin and Losartan in Preclinical Models of Post-Traumatic Elbow Contracture.DOCX by Michael A. David (12111687)

Image2_Pleiotropic Effects of Simvastatin and Losartan in Preclinical Models of Post-Traumatic Elbow Contracture.TIF by Michael A. David (12111687)

Table1_Pleiotropic Effects of Simvastatin and Losartan in Preclinical Models of Post-Traumatic Elbow Contracture.DOCX by Michael A. David (12111687)

Effects of Green Tea Extract on Insulin Resistance and Glucagon-Like Peptide 1 in Patients with Type 2 Diabetes and Lipid Abnormalities: A Randomized, Double-Blinded, and Placebo-C... by Chia-Yu Liu (532886)

“…Adiponectin, apolipoprotein A1, and apolipoprotein B100 increased significantly in both arms, but only glucagon-like peptide 1 increased in the therapeutic arm. …”

Agrin is depleted from NMJs following conditional deletion in adults. by Melanie A. Samuel (253429)

“…<p>A. Schematic of the method used to delete agrin from subsets of motoneurons. …”

Mutually exclusive expression of Flag-Dmp1 and Ki67 in <i>MDTG;neu</i> tumors. by Elizabeth A. Fry (477763)

“…<p>A. Total tumor weight harvested at sacrifice. The amount of tumors recovered at sacrifice (4 weeks after the first tumor was found) was significantly decreased in all three transgenic strains. …”

Deficits and Disparities in Early Uptake of GLP-1 Receptor Agonists and SGLT2 Inhibitors among Medicare-insured Adults Following a New Diagnosis of Cardiovascular Disease or Heart... by Sara J. Cromer (13136821)

“…</p> <p>Results: IRs of GLP1-RA or SGLT2i initiation increased over time but remained low (<0.6 initiations per 100 person-months) in all years studied. Medication initiation was less common among those of Black or Other race/ethnicity (HR 0.81 [95% confidence interval (CI) 0.79-0.84] and HR 0.84 [95%CI 0.75-0.95], respectively) and decreased with increasing SDI (HR 0.96 [95%CI 0.96-0.97]). …”

Bone marrow and peripheral blood and bone marrow white blood cells (WBC) count and FACS analysis, experiment 2. by Valentina A. Carozzi (458128)

“…The number of hematopoietic cells in the peripheral blood expressing the pan-leukocyte antigen CD45 is also reported (C). A comparable immune-suppression was observed in both X-Ray and X-Ray-bortezomib-treated animals after the irradiation induction and maintenance doses, as shown by the decreased cellularity and leukopenia in the BM and spleen of irradiated mice, regardless of bortezomib treatment.…”

Effect of Go-6976 on S6 Kinase activity. by Katherine A. Robinson (645068)

“…<p>Adipocytes were preincubated for 18 h in 5 mM glucose (IS) or in 25 mM glucose+0.6 nM insulin (GI-IR). <b>A.</b> Acute insulin treatment (100 nM for 15 min) stimulated activating phosphorylation of S-6 kinase (8–10-fold) and of its substrate S-6 ribosomal protein (4–5-fold). …”

Inverted brightfield images of mock- and HSV-1-infected neurons. by Colleen A. Mangold (10344932)

“…<p>Different HSV-1 strains are depicted in columns, and 12 vs 24 hpi in rows. Images from <b><a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1009441#ppat.1009441.g005" target="_blank">Fig 5A</a></b> were inverted and brightness and contrast were equally adjusted to better visualize changes in neurite adhesion and fasciculation following infection. …”

Predictions of the Brownian zipper model. by Emmet A. Francis (13450211)

“…<p>(A) A model cell spreading on the highest tested ligand density (100%) quickly approaches a spherical cap morphology. …”

Correlation analyses between studied genes. by Marwa A. Ali (11973086)

“…ROC curve analysis revealed that sensitivity and specificity tests for <i>NEAT-1</i> and IL-6 levels in the diagnosis of cases illustrated a sensitivity of (100% and 97.9%) and a specificity of (85% and 100%) at cut-off values (0.985 and 12.55), respectively. …”

Data Sheet 1_Endophytic and antagonistic Bacillus amyloliquefaciens 8SE-IF1-derived nanoparticles encumber phytopathogenic oomycetes, fungi, bacteria, and viruses with enhanced gro... by A. Mary Sharmila (21898730)

“…<p>Green synthesis of nanoparticles (Gs-NPs) of antimicrobial compounds from endophytic and antagonistic microbes is a novel strategy for managing plant diseases caused by different pathogens. …”