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12021
Data_Sheet_1_Electroacupuncture for the Prevention of Postoperative Cognitive Dysfunction Among Older Adults Undergoing Hip and Knee Arthroplasty: A Systematic Review and Meta-Anal...
Published 2022“…<p>Background: Postoperative cognitive dysfunction (POCD) is a common surgical complication in elderly patients undergoing hip and knee replacement. …”
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12022
Data_Sheet_1_The Efficacy and Safety of Pirfenidone Combined With Immunosuppressant Therapy in Connective Tissue Disease-Associated Interstitial Lung Disease: A 24-Week Prospective...
Published 2022“…However, in IIM patients with a non-UIP tendency, PFD displayed better therapeutic effects than the control (10.50 vs. 1.00%). …”
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12023
Increased hydrophilic plasma bile acids are correlated with protection from adiposity in skin-specific stearoyl-CoA desaturase-1 deficient mice
Published 2018“…<div><p>Stearoyl-CoA desaturase 1 (SCD1) catalyzes the rate limiting step in monounsaturated fatty acid synthesis by inserting a double bond at the delta-9 position of long-chain fatty acids. …”
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12024
FIGURE 2 from D-2-HG Inhibits <i>IDH1<sup>mut</sup></i> Glioma Growth via FTO Inhibition and Resultant m6A Hypermethylation
Published 2024“…IDH1<sup>mut</sup> inhibitors (C35 = 2 µmol/L; AG881 = 1 µmol/L) enhance growth of <i>IDH1<sup>mut</sup></i><b></b>patient-derived gliomaspheres HK252 (<b>A</b>) and HK211 (<b>B</b>). <b>C,</b> Effect of <i>IDH1<sup>mut</sup></i> forced expression in <i>IDH1<sup>wt</sup></i> gliomaspheres (HK385, HK217, and HK250) on gliomasphere growth relative to vector control [ANOVA, <i>F</i>(1,1056) = 199.0, <i>P</i> ≤ 0.0001; asterisks indicate <i>post hoc</i> Newman–Keuls comparison with vector], showing decreased overall growth in <i>IDH1<sup>mut</sup></i>. …”
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12025
Phase diagram describing the fitness gains of QS over AO as a function of constitutive growth rate (λ<sub>0</sub>) and public good production cost (<i>c</i>).
Published 2022“…When <i>c</i> = 0, there are a small number of initial compositions where which decreases as λ<sub>0</sub> increases. …”
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12026
Can Topical Insect Repellents Reduce Malaria? A Cluster-Randomised Controlled Trial of the Insect Repellent <i>N,N</i>-diethyl-<i>m</i>-toluamide (DEET) in Lao PDR
Published 2013“…Intention to treat analysis found no effect from the use of repellent on malaria incidence (hazard ratio: 1.00, 95% CI: 0.99–1.01, p = 0.868). A higher socio-economic score was found to significantly decrease malaria risk (hazard ratio: 0.72, 95% CI: 0.58–0.90, p = 0.004). …”
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12027
DataSheet1_Effects of the peripheral CB1 receptor antagonist JD5037 in mono— and polytherapy with the AMPK activator metformin in a monocrotaline-induced rat model of pulmonary hyp...
Published 2022“…Animals received metformin (100 mg/kg), JD5037 (3 mg/kg), or a combination of both once daily for 21 days. …”
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12028
Image_1_Subpopulation treatment effect pattern plot analysis: a prognostic model for distant recurrence-free survival to estimate delayed adjuvant chemotherapy initiation effect in...
Published 2023“…Kaplan-Meier plots showed that in the discovery set, patients with TTC>30 days experienced a 17.5% decrease in 10-year DRFS rate (95%CI=6.7-28.3), and the impact was more remarkable in patients who belong to the high-risk subgroup (53.3% decrease in 10 years-DRFS rate). …”
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12029
Table1_Temporal trends in the prevalence and death of ischemic heart disease in women of childbearing age from 1990 to 2019: a multilevel analysis based on the Global Burden of Dis...
Published 2024“…Conversely, the ASDR decreased to 11.11 (95% UI, 10.10–12.30) per 100,000 individuals. …”
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12030
Datasheet1_Temporal trends in the prevalence and death of ischemic heart disease in women of childbearing age from 1990 to 2019: a multilevel analysis based on the Global Burden of...
Published 2024“…Conversely, the ASDR decreased to 11.11 (95% UI, 10.10–12.30) per 100,000 individuals. …”
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12031
DataSheet_1_A Novel Glucocorticoid and Androgen Receptor Modulator Reduces Viral Entry and Innate Immune Inflammatory Responses in the Syrian Hamster Model of SARS-CoV-2 Infection....
Published 2022“…Results indicated that oral administration of PT150 caused a dose-dependent decrease in replication of SARS-CoV-2 in lung, as well as in expression of ACE2 and TMPRSS2. …”
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12032
Table 2_Effects of low-frequency and high-frequency electroacupuncture pretreatment on the COX-2/mPGES-1/PGE2 pathway in a rat model of cold-coagulation dysmenorrhea.docx
Published 2025“…</p>Methods<p>A cold-coagulation type dysmenorrhea model was established in rats, which were divided into the control group, model group, low-frequency electroacupuncture group (2/10 Hz), and high-frequency electroacupuncture group (20/100 Hz). …”
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12033
Table 4_Effects of low-frequency and high-frequency electroacupuncture pretreatment on the COX-2/mPGES-1/PGE2 pathway in a rat model of cold-coagulation dysmenorrhea.docx
Published 2025“…</p>Methods<p>A cold-coagulation type dysmenorrhea model was established in rats, which were divided into the control group, model group, low-frequency electroacupuncture group (2/10 Hz), and high-frequency electroacupuncture group (20/100 Hz). …”
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12034
Table 3_Effects of low-frequency and high-frequency electroacupuncture pretreatment on the COX-2/mPGES-1/PGE2 pathway in a rat model of cold-coagulation dysmenorrhea.xlsx
Published 2025“…</p>Methods<p>A cold-coagulation type dysmenorrhea model was established in rats, which were divided into the control group, model group, low-frequency electroacupuncture group (2/10 Hz), and high-frequency electroacupuncture group (20/100 Hz). …”
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12035
Table 1_Effects of low-frequency and high-frequency electroacupuncture pretreatment on the COX-2/mPGES-1/PGE2 pathway in a rat model of cold-coagulation dysmenorrhea.xlsx
Published 2025“…</p>Methods<p>A cold-coagulation type dysmenorrhea model was established in rats, which were divided into the control group, model group, low-frequency electroacupuncture group (2/10 Hz), and high-frequency electroacupuncture group (20/100 Hz). …”
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12036
datasheet1_Antihypertensive Effect of a Novel Angiotensin II Receptor Blocker Fluorophenyl Benzimidazole: Contribution of cGMP, Voltage-dependent Calcium Channels, and BKCa Channel...
Published 2021“…</p><p>Results: FPD significantly decreased blood pressure in SHR. It relaxed superior mesenteric arteries in a concentration-dependent manner and significantly inhibited angiotensin II-induced contraction. …”
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12037
Table_1_Global, regional, and national burden of syphilis, 1990–2021 and predictions by Bayesian age-period-cohort analysis: a systematic analysis for the global burden of disease...
Published 2024“…Next, a differential analysis of syphilis risk factors was performed. …”
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12038
Data_Sheet_1_Ultrasound-guided anterior iliopsoas muscle space block effectively reduces intraoperative hypotension in elderly adults undergoing hip surgery: A randomised controlle...
Published 2023“…</p>Results<p>Compared to the posterior group, the iliopsoas space block group had a decreased median frequency of IOH [1.09 (0–2. 14) vs. 3 (1.6–4.8), p = 0.001, respectively] along with lower absolute [5 (0–10) min] and relative [minutes below systolic blood pressure of 100 mmHg in % of total anaesthesia time, 6.67 (0–7.65)] duration of IOH compared to the posterior group [35 (10–45) min, p = 0.008; 37.6 (12.99–66.18), p = 0.004, respectively]. …”
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12039
Data Sheet 1_Evolving trends and burden of idiopathic epilepsy among children (0–14 years), 1990–2021: a systematic analysis for the Global Burden of Disease study 2021.zip
Published 2025“…The ASIR increased by 0.27% from 55.74 to 61.35 per 100,000 population from 1990 to 2021. In contrast, ASPR (AAPC = −0.03), ASMR (AAPC = −1.60), and ASDR (AAPC = −1.01) all decreased. …”
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12040
Data Sheet 1_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.pdf...
Published 2025“…High-SDI regions, conversely, exhibited a resurgence in varicella and herpes zoster (ASIR: 1,300/100,000) driven by aging populations. …”