Model Studies of 6,7-Indolequinone Cofactors of Quinoprotein Amine Dehydrogenases by Yoko Murakami (423119)

“…The reactivity of indolequinones <b>2</b> and <b>3</b> is further decreased due to their stronger electron-donating substituents at C-4. …”

Measured time series from e-Rep circuit showing the period-1 LC (protein <i>A</i>-yellow, <i>B</i>-blue and <i>C</i>-purple). by Edward H. Hellen (346773)

“…<p>β = 0.1, α = 46, n = 3, <i>k</i>_S1 = 0.025, <i>k</i>_S0 = 1, and η = 1. (a) κ = 14, (b) κ = 19. Note that the protein oscillation amplitudes are larger in frame (a) than (b) since the vertical scale is 200 mV/div in (a) and 100 mV/div in (b). …”

The 2.1 Å Resolution Structure of Cyanopindolol-Bound β₁-Adrenoceptor Identifies an Intramembrane Na⁺ Ion that Stabilises the Ligand-Free Receptor by Jennifer L. Miller-Gallacher (541986)

“…We have determined the structure of an ultra-thermostable β₁AR mutant bound to the weak partial agonist cyanopindolol to 2.1 Å resolution. High-quality crystals (100 μm plates) were grown in lipidic cubic phase without the assistance of a T4 lysozyme or BRIL fusion in cytoplasmic loop 3, which is commonly employed for GPCR crystallisation. …”

IAA application on <i>pin1</i> meristem leads to local tissue softening and pectin de-methyl-esterification in sub-epidermal tissues. by Siobhan A. Braybrook (388465)

“…Note that meristem curvature does not correlate with areas of decreased E_A, and that there is no bulging of the meristem accompanying decreased rigidity. …”

Table1_Tang Luo Ning, a Traditional Chinese Compound Prescription, Ameliorates Schwannopathy of Diabetic Peripheral Neuropathy Rats by Regulating Mitochondrial Dynamics In Vivo and... by Jiayue Zhu (10800972)

“…Our results showed that TLN increased ATP levels (0.38 of model, 0.69 of HTLN, 0.61 of LTLN, P＜0.01; 0.52 of 150 mM glucose, 1.00 of 10% TLN, P＜0.01, 0.94 of 1% TLN, P＜0.05), MMP (0.56 of 150 mM glucose, P＜0.01, 0.75 of 10% TLN, P＜0.05, 0.83 of 1% TLN, P＜0.01), and mtDNA (0.32 of 150 mM glucose, 0.43 of 10% TLN, P＜0.01) while decreased Ca²⁺ (1.54 of model, 1.06 of HTLN, 0.96 of LTLN, P＜0.01) to improve mitochondrial function in vivo and in vitro. …”

Image1_Tang Luo Ning, a Traditional Chinese Compound Prescription, Ameliorates Schwannopathy of Diabetic Peripheral Neuropathy Rats by Regulating Mitochondrial Dynamics In Vivo and... by Jiayue Zhu (10800972)

“…Our results showed that TLN increased ATP levels (0.38 of model, 0.69 of HTLN, 0.61 of LTLN, P＜0.01; 0.52 of 150 mM glucose, 1.00 of 10% TLN, P＜0.01, 0.94 of 1% TLN, P＜0.05), MMP (0.56 of 150 mM glucose, P＜0.01, 0.75 of 10% TLN, P＜0.05, 0.83 of 1% TLN, P＜0.01), and mtDNA (0.32 of 150 mM glucose, 0.43 of 10% TLN, P＜0.01) while decreased Ca²⁺ (1.54 of model, 1.06 of HTLN, 0.96 of LTLN, P＜0.01) to improve mitochondrial function in vivo and in vitro. …”

Image2_Tang Luo Ning, a Traditional Chinese Compound Prescription, Ameliorates Schwannopathy of Diabetic Peripheral Neuropathy Rats by Regulating Mitochondrial Dynamics In Vivo and... by Jiayue Zhu (10800972)

“…Our results showed that TLN increased ATP levels (0.38 of model, 0.69 of HTLN, 0.61 of LTLN, P＜0.01; 0.52 of 150 mM glucose, 1.00 of 10% TLN, P＜0.01, 0.94 of 1% TLN, P＜0.05), MMP (0.56 of 150 mM glucose, P＜0.01, 0.75 of 10% TLN, P＜0.05, 0.83 of 1% TLN, P＜0.01), and mtDNA (0.32 of 150 mM glucose, 0.43 of 10% TLN, P＜0.01) while decreased Ca²⁺ (1.54 of model, 1.06 of HTLN, 0.96 of LTLN, P＜0.01) to improve mitochondrial function in vivo and in vitro. …”

Image1_Tang Luo Ning, a Traditional Chinese Compound Prescription, Ameliorates Schwannopathy of Diabetic Peripheral Neuropathy Rats by Regulating Mitochondrial Dynamics In Vivo and... by Jiayue Zhu (10800972)

“…Our results showed that TLN increased ATP levels (0.38 of model, 0.69 of HTLN, 0.61 of LTLN, P＜0.01; 0.52 of 150 mM glucose, 1.00 of 10% TLN, P＜0.01, 0.94 of 1% TLN, P＜0.05), MMP (0.56 of 150 mM glucose, P＜0.01, 0.75 of 10% TLN, P＜0.05, 0.83 of 1% TLN, P＜0.01), and mtDNA (0.32 of 150 mM glucose, 0.43 of 10% TLN, P＜0.01) while decreased Ca²⁺ (1.54 of model, 1.06 of HTLN, 0.96 of LTLN, P＜0.01) to improve mitochondrial function in vivo and in vitro. …”

Table1_Tang Luo Ning, a Traditional Chinese Compound Prescription, Ameliorates Schwannopathy of Diabetic Peripheral Neuropathy Rats by Regulating Mitochondrial Dynamics In Vivo and... by Jiayue Zhu (10800972)

“…Our results showed that TLN increased ATP levels (0.38 of model, 0.69 of HTLN, 0.61 of LTLN, P＜0.01; 0.52 of 150 mM glucose, 1.00 of 10% TLN, P＜0.01, 0.94 of 1% TLN, P＜0.05), MMP (0.56 of 150 mM glucose, P＜0.01, 0.75 of 10% TLN, P＜0.05, 0.83 of 1% TLN, P＜0.01), and mtDNA (0.32 of 150 mM glucose, 0.43 of 10% TLN, P＜0.01) while decreased Ca²⁺ (1.54 of model, 1.06 of HTLN, 0.96 of LTLN, P＜0.01) to improve mitochondrial function in vivo and in vitro. …”

Image2_Tang Luo Ning, a Traditional Chinese Compound Prescription, Ameliorates Schwannopathy of Diabetic Peripheral Neuropathy Rats by Regulating Mitochondrial Dynamics In Vivo and... by Jiayue Zhu (10800972)

“…Our results showed that TLN increased ATP levels (0.38 of model, 0.69 of HTLN, 0.61 of LTLN, P＜0.01; 0.52 of 150 mM glucose, 1.00 of 10% TLN, P＜0.01, 0.94 of 1% TLN, P＜0.05), MMP (0.56 of 150 mM glucose, P＜0.01, 0.75 of 10% TLN, P＜0.05, 0.83 of 1% TLN, P＜0.01), and mtDNA (0.32 of 150 mM glucose, 0.43 of 10% TLN, P＜0.01) while decreased Ca²⁺ (1.54 of model, 1.06 of HTLN, 0.96 of LTLN, P＜0.01) to improve mitochondrial function in vivo and in vitro. …”

Fig 7 - by Caspar A. S. Pouw (9579630)

“…This ratio, which we further scale to its value at week 18, displays a ≈100% growth between week 18 and 26, to confirm that the increment of passengers contributes only for 150% of the overall exposure time growth.…”

Expression of emGFP-Igf2bp1^Y399E in RGCs disrupts axon outgrowth <i>in vivo</i>. by John A. Gaynes (790924)

“…<p>(a-c) Dorsal confocal projections (30x silicone immersion lens) of Tg(<i>isl2b</i>:emGFP) (a), Tg(<i>isl2b</i>:emGFP-Igf2bp1)^wt (b), and Tg(<i>isl2b</i>:emGFP-Igf2bp1)^Y399E (c) 3 dpf transient transgenic embryos. …”

Data_Sheet_1_Examining Genetic Variation in Maize Inbreds and Mapping Oxidative Stress Response QTL in B73-Mo17 Nearly Isogenic Lines.docx by Crystal A. Sorgini (6915314)

“…In Mo17 NILs, a significant leaf damage QTL was identified at 161Mb on chromosome 2. …”

Synergistic effect of nano-selenium and metformin on type 2 diabetic rat model: Diabetic complications alleviation through insulin sensitivity, oxidative mediators and inflammatory... by Shaymaa A. Abdulmalek (4025555)

“…Experimental animals either treated with mono-therapeutic-two doses Se-NPs (0.1 and 0.4 mg/kg) and/or MET (100 mg/kg) alone as well as the combined therapy resulted in a remarkable protective anti-diabetic effect illustrated by significant decreases in fasting blood glucose and insulin levels after 8 weeks treatment. …”

Data_Sheet_1_Extracellular Vesicles Released by Human Induced-Pluripotent Stem Cell-Derived Cardiomyocytes Promote Angiogenesis.PDF by Julie A. Dougherty (463061)

“…<p>Although cell survival post-transplantation is very low, emerging evidence using stem cell therapy for myocardial repair points toward a primary role of paracrine signaling mechanisms as the basis for improved cardiac function, decreased fibrosis, and increased angiogenesis. …”

Effects of temperature on modeled neurons: Bursting emergence. by Matías A. Goldin (424331)

“…Decreasing temperature affects the interspike interval, which widens in all cases, leading to a reduced number of spikes. …”

DataSheet_1_Correlative analysis from a phase I clinical trial of intrapleural administration of oncolytic vaccinia virus (Olvi-vec) in patients with malignant pleural mesothelioma... by Navin K. Chintala (14631764)

“…Vaccinia virus was detectable in tumor cells 2-5 days post-treatment, and treatment was associated with a decrease in tumor cell density and an increase in immune cell density as assessed by a pathologist blinded to the clinical observations. …”

Image_1_Piver Type II vs. Type III Hysterectomy in the Treatment of Early-Stage Cervical Cancer: Midterm Follow-up Results of a Randomized Controlled Trial.JPEG by Hengzi Sun (6017819)

“…The 2-year DFS rate in the type II group was 100% compared with 97.9% in the type III group (P > 0.05). …”

Supplementary Material for: A Case of Granulocyte-Colony-Stimulating Factor-Producing Non-Small Cell Lung Cancer under Steroid Treatment and with Poor Performance Status that respo... by Egusa H. (19645753)

“…Driver mutations were negative, and PD-L1, tumor proportion score, was highly expressed at 100%. Thus, pembrolizumab was started. Subsequently, the WBC count decreased, and the tumor shrank, indicating partial response. …”

Table_1_Association of Yogurt and Dietary Supplements Containing Probiotic Consumption With All-Cause and Cause-Specific Mortality in US Adults: A Population-Based Cohort Study.XLS by Ping Lin (146330)

“…Weighted Cox proportional hazards models suggested that yogurt consumption was inversely associated with all-cause mortality (adjusted hazard ratio (HR), 0.83 [95% confidence interval (CI), 0.71–0.98]) but not cardiovascular mortality (adjusted HR, 0.68 [95%CI, 0.43–1.08]) and cancer mortality (adjusted HR, 1.00 [95%CI, 0.72–1.38]). However, dietary supplements containing probiotic were not associated with decreased all-cause and cause-specific mortality.…”