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11841
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11842
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11843
Image_1_The Predictive Value of Estrogen Receptor 1 on Adjuvant Chemotherapy in Locally Advanced Colorectal Cancer: A Retrospective Analysis With Independent Validation and Its Pot...
Published 2020“…ESR1 expression was significantly correlated with 5-flurouracil (5-FU)-based adjuvant chemotherapy in training with an HR of 1.792 (95%CI: 1.100–2.921, p = 0.019). Downregulation of ESR1 was related with enhanced chemosensitivity to 5-FU in CRC cell lines, while upregulation of ESR1 was correlated with decreased chemosensitivity.…”
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11844
Table_1_Xiao-Shen-Formula, a Traditional Chinese Medicine, Improves Glomerular Hyper-Filtration in Diabetic Nephropathy via Inhibiting Arginase Activation and Heparanase Expression...
Published 2018“…Studies were performed using control, diabetic DN, DN treated with XSF groups (1 g/kg/d, LXSF or 3 g/kg/d, HXSF) for 6 weeks and hGECs were post-treated with mice serum containing HXSF (MS-HXSF) and arginase inhibitor (ABH, 100 μM) in high glucose medium. HXSF treatment restored STZ-induced renal hyper-filtration, glomerulosclerosis, renal microvascular remodeling and the increased levels of systemic reactive oxidative species and inflammatory cytokines, accompanied by preventing the decreased expression of glomerular heparin sulfate and the increased levels of cortical heparanase and argianse2 protein and arginase activity. …”
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11845
Supplementary Material for: Efficacy of Rituximab for Minimal Change Disease and Focal Segmental Glomerulosclerosis with Frequently Relapsing or Steroid-Dependent Nephrotic Syndrom...
Published 2023“…The relapse frequency, calculated as the ratio of relapse times to follow-up years, significantly decreased after rituximab treatment [0.04 (0.00, 0.08) vs. 1.71 (1.00, 2.45), P < 0.001]. …”
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11846
Table 1_Durability of benralizumab effectiveness in severe eosinophilic asthma patients with and without chronic rhinosinusitis with nasal polyps: a post hoc analysis from the ANAN...
Published 2025“…After 96 weeks of treatment, the annual exacerbation rate (AER) decreased in both groups, with CRSwNP patients achieving considerable reductions than No-CRSwNP patients (severe AER dropped by 100% and 95.6%, respectively). …”
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11847
Data Sheet 1_Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040.zip
Published 2025“…The global age-standardized rates per 100,000 were: prevalence 22.2 (19.8 - 24.8), deaths 0.2 (0.2 - 0.2), and DALYs 11.4 (9.8 - 13.2). …”
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11848
Data Sheet 2_Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040.docx
Published 2025“…The global age-standardized rates per 100,000 were: prevalence 22.2 (19.8 - 24.8), deaths 0.2 (0.2 - 0.2), and DALYs 11.4 (9.8 - 13.2). …”
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11849
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11850
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11851
Outline of results for spine maturation.
Published 2017“…Panel (d): Ratio of head and neck radii (left) and volumes (right) for a number of actin filaments <i>N</i> = 25, 50, 100, 150, 200 (lower to upper curves). …”
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11852
Difference model of cross-hemispheric LIP activity driving temporal production.
Published 2012“…The vertical dashed line represents the time at which saccades are signaled (motor delay accounts for the remaining 100 ms prior to saccade initiation). (B) The green line displays the difference between the integrated rate aligned to the peripheral target (A, blue to red) minus the integrated rate aligned to the peripheral target (A, red to blue) prior to saccade initiation (only the positive value differences are shown). …”
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11853
Incomplete Albumin-Cre-mediated deletion of <i>Rps6</i> results in mosaicism for RPS6 expression across the neonatal liver.
Published 2023“…After stripping, the blot was incubated with a p<sup>32</sup>-radiolabeled 18S rRNA probe. (D) Graph showing quantitation of the Northern blot shown in (C) demonstrating that <i>Rps6</i> mRNA levels are decreased by 50–60% in ΔS6 livers relative to WT. …”
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11854
Data Sheet 1_A population-based analysis of the global burden of epilepsy across all age groups (1990–2021): utilizing the Global Burden of Disease 2021 data.pdf
Published 2024“…</p>Finding<p>In 2021, there were 24,220,856 (95% UI: 18,476,943–30,677,995) patients with epilepsy, with an age-standardized prevalence rate (ASPR) of 307.38 per 100,000 persons (95% UI: 234.71–389.02) and an age-standardized incidence rate (ASIR) of 42.821 per 100,000 persons (95% UI: 31.24–53.72).The global age-standardized mortality rate (ASMR) of epilepsy was 1.74 per 100,000 population (95% UI: 1.46–1.92); The age-standardized DALYs rate (ASDR) were 177.85 per 100,000 population (95% UI: 137.66–225.90); 154.25 per 100,000 population for females [114.73–201.76], and 201.29 per 100,000 population for males [157.93–252.74]. …”
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11855
Table 1_The burden of gastric cancer attributed to high salt intake and predictions through the year 2042: a cross-national comparative analysis of China, Japan, and South Korea.do...
Published 2025“…Globally, ASMR decreased from 1.74 per 100,000 in 1990 to 0.89 per 100,000 in 2021 (EAPC = −2.26). …”
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11856
Data_Sheet_1_Response of Nitrate Processing to Bio-labile Dissolved Organic Matter Supply Under Variable Oxygen Conditions in a Sandy Beach Seepage Face.PDF
Published 2021“…Compared with the active response of sediment microbiota to NO<sub>3</sub><sup>–</sup> additions, the supply of glucose (approximately 300 μM final concentration added) did not significantly change the NO<sub>3</sub><sup>–</sup> removal efficiency under aerobic conditions (dissolved oxygen saturation approximately 100%). Similarly, an insignificant increase of NO<sub>3</sub><sup>–</sup> removal rate after glucose amendment of the circulating water was obtained when dissolved oxygen (DO) saturation decreased to approximately 70% in the input solution. …”
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11857
DataSheet_1_Spatiotemporal Trends in the Incidence of Gastrointestinal Neoplasms in Wuwei City of Northwestern China From 1995 to 2016: A Hospital-Based Retrospective Observational...
Published 2021“…</p>Results<p>Among the 19,137 new inpatients identified with GI neoplasms in Wuwei, gastric cancer was the leading cause of morbidity, followed by cancers of the esophagus, colorectum, gastric cardia, liver, and pancreas with ASIRs of 21.8, 11.0, 5.8, 5.7, 4.4, and 1.7 per 100,000 person-years, respectively. Overall, there was a steady increase in the ASIR for all GI neoplasms, and male cases were 2.1 times more frequent than female cases. …”
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11858
Polymorphisms of −174G>C and −572G>C in the Interleukin 6 (IL-6) Gene and Coronary Heart Disease Risk: A Meta-Analysis of 27 Research Studies
Published 2012“…On the contrary, the −572C allele was associated with a decreased risk of CHD when compared with the −572G allele (ORs = 0.79, 95%CI = 0.68 to 0.93). …”
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11859
DataSheet1_Global burden of chronic kidney disease in adolescents and young adults, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.docx
Published 2024“…</p>Results<p>From 1990 to 2019, the global age-specific incidence rate (per 100,000 population) significantly increased from 25.04 (95% confidence interval 18.51, 31.65) to 32.21 (23.73, 40.81) for early-onset CKD. …”
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11860
Differential antibody and cytokine responses associated with resistance to <i>T. cruzi</i>.
Published 2010“…<p>These plots model responses in <i>T. cruzi</i> infected C57Bl/6 and Balb/c mice compared to control mice inoculated with heat-inactivated parasite (original data in <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000733#pntd-0000733-g001" target="_blank">Fig 1</a>–<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000733#pntd-0000733-g002" target="_blank"></a><a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000733#pntd-0000733-g003" target="_blank"></a><a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000733#pntd-0000733-g004" target="_blank"></a><a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000733#pntd-0000733-g005" target="_blank">5</a>) and show the association of parasite-specific antibody responses in the blood and spleen with decreased polyclonal antibody responses and differential cytokine expression (kinetics and quality summarized here). …”