Image_1_Safety and Efficacy of Sintilimab and Anlotinib as First Line Treatment for Advanced Hepatocellular Carcinoma (KEEP-G04): A Single-Arm Phase 2 Study.tif by Xiaofeng Chen (392939)

“…Grade 3 TRAEs occurred in 8 (40.0%) patients, the most common being decreased platelet count (10.0%) and increased γ-glutamyl transferase (10.0%). …”

Image_2_Safety and Efficacy of Sintilimab and Anlotinib as First Line Treatment for Advanced Hepatocellular Carcinoma (KEEP-G04): A Single-Arm Phase 2 Study.tif by Xiaofeng Chen (392939)

“…Grade 3 TRAEs occurred in 8 (40.0%) patients, the most common being decreased platelet count (10.0%) and increased γ-glutamyl transferase (10.0%). …”

Table_1_Safety and Efficacy of Sintilimab and Anlotinib as First Line Treatment for Advanced Hepatocellular Carcinoma (KEEP-G04): A Single-Arm Phase 2 Study.docx by Xiaofeng Chen (392939)

“…Grade 3 TRAEs occurred in 8 (40.0%) patients, the most common being decreased platelet count (10.0%) and increased γ-glutamyl transferase (10.0%). …”

Deletion of <i>Rps6</i> in adult liver induces hepatocyte apoptosis and triggers regeneration. by Sarah A. Comerford (3854917)

“…Scale bars: a), c) and d), 100μ; b) and e), 50μ. (F) Photomicrographs of IHC for PCNA, phospho-RPS6^(Ser235/6) and pan-cytokeratin (CK) on livers of ΔS6^dox mice provided with dox for 54 days showing that regenerating nodules contain PCNA- and phospho-RPS6^(Ser235/6)-positive immature hepatocytes while pan-CK-positive cells comprise the dr. …”

FLIM imaging of live mouse intestinal organoids stained with HXT (1.5 μM, 4 h) and BrdU. by Irina A. Okkelman (3544946)

“…(<b>e</b>) FLIM image of an individual crypt from organoid incubated with BrdU (100 μM, 4 h) shows fewer nuclei with decreased τ_m. …”

Infection related impact of different <i>Schistosoma mansoni</i> strains on host pathology. by Tim A. Dannenhaus (19959583)

“…<p>(A) Liver and spleen pathology of mice infected with 100 cercariae of the BH, LB and PR strain; the bar corresponds to 1 cm. …”

Table 2_Global, regional, and national burden of intracerebral hemorrhage and attributable risk factors in youths and young adults, 1990–2021: a statistical analysis of incidence,... by Bing Wu (172312)

“…The incidence rate declined from 11.31 (95% UI, 8.56, 14.27) per 100,000 individuals in 1990 to 8.30 (95% UI, 6.46, 10.19) per 100,000 individuals in 2021, an overall decrease of −26.62% (95% UI, −30.85 to −22.24). …”

Table 1_Global, regional, and national burden of intracerebral hemorrhage and attributable risk factors in youths and young adults, 1990–2021: a statistical analysis of incidence,... by Bing Wu (172312)

“…The incidence rate declined from 11.31 (95% UI, 8.56, 14.27) per 100,000 individuals in 1990 to 8.30 (95% UI, 6.46, 10.19) per 100,000 individuals in 2021, an overall decrease of −26.62% (95% UI, −30.85 to −22.24). …”

The 2.1 Å Resolution Structure of Cyanopindolol-Bound β₁-Adrenoceptor Identifies an Intramembrane Na⁺ Ion that Stabilises the Ligand-Free Receptor by Jennifer L. Miller-Gallacher (541986)

“…We have determined the structure of an ultra-thermostable β₁AR mutant bound to the weak partial agonist cyanopindolol to 2.1 Å resolution. …”

Table 1_The burden of gastric cancer attributed to high salt intake and predictions through the year 2042: a cross-national comparative analysis of China, Japan, and South Korea.do... by Wei Liu (20030)

“…Globally, ASMR decreased from 1.74 per 100,000 in 1990 to 0.89 per 100,000 in 2021 (EAPC = −2.26). …”

Data Sheet 1_Identification of sepsis biomarkers through glutamine metabolism-mediated immune regulation: a comprehensive analysis employing mendelian randomization, multi-omics in... by Zhuang’e Shi (22089701)

“…RT-qPCR revealed decreased SRSF7 expression and increased RAB13, E2F2, and S100A8 expression in sepsis.…”

Outline of results for spine maturation. by C. A. Miermans (3716515)

“…For these plots we used <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0170113#pone.0170113.e029" target="_blank">Eq 2</a> with . …”

Gene Content of the Differentially Hybridizing Virulence Loci between <i>B. bronchiseptica</i> Complex I and IV, as Determined by CGH by Dimitri A Diavatopoulos (274876)

“…The BP probe of <i>tcfA</i> was 100% similar to <i>B. pertussis</i> Tohama and 85.1% similar to <i>B. bronchiseptica</i> RB50. …”

Table1_Effectiveness and safety of tenofovir amibufenamide and its comparison with tenofovir alafenamide in patients with chronic hepatitis B: results from a retrospective real-wor... by Lanqing Li (11505488)

“…Furthermore, tenofovir alafenamide-treated patients were enrolled using the propensity score matching method (PSM). We assessed the virological response (VR, HBV DNA < 100 IU/mL) rate, renal function, and blood lipid changes during 24 weeks of treatment.…”

Kidney-Specific Reduction of Oxidative Phosphorylation Genes Derived from Spontaneously Hypertensive Rat by Jason A. Collett (787818)

“…After breeding a female Okamoto-Aoki SHR (SAP = 188mmHg) with Brown Norway (BN) males (SAP = 100 and 104 mmHg), hypertensive female progeny were backcrossed with founder BN for 5 consecutive generations in order to maintain the SHR mitochondrial genome in offspring that contain over increasing BN nuclear genome. …”

Image_1_Subpopulation treatment effect pattern plot analysis: a prognostic model for distant recurrence-free survival to estimate delayed adjuvant chemotherapy initiation effect in... by Zaida Morante (9292533)

“…Delaying in time to start adjuvant chemotherapy (TTC) has been related to an increased risk of distant recurrence-free survival (DRFS). We aimed to develop a prognostic model to estimate the effects of delayed TTC among TNBC risk subgroups.…”

Datasheet1_Deep vein thrombosis and pulmonary embolism: a prospective, observational study to evaluate diagnostic performance of the Tina-quant D-Dimer Gen.2 assay.docx by Thomas Bertsch (360246)

“…Background<p>D-Dimer testing is a diagnostic tool for exclusion of deep vein thrombosis (DVT) and pulmonary embolism (PE). …”

(goes with Fig 5). by Patrick A. Carroll (11586792)

“…(<b>D</b>) IHC analysis of WT versus MLX^KO testis and epididymis stained for the proliferation marker Ki-67 (100×, scale bar = 400 uM). Asterisks marks acellular tubule with decreased Ki-67. …”

Long-term trends in incidence and risk factors for ischaemic stroke subtypes: Prospective population study of the South London Stroke Register by Hatem A. Wafa (5823872)

“…Between 2000–2003 and 2012–2015, the age-adjusted incidence of IS decreased by 43% from 137.3 to 78.4/100,000/year (incidence rate ratio [IRR] 0.57, 95% CI 0.5–0.64). …”

Data_Sheet_1_Agriculture by Irrigation Modifies Microbial Communities and Soil Functions Associated With Enhancing C Uptake of a Steppe Semi-Arid Soil in Northern Patagonia.PDF by Juan P. Frene (12227753)

“…To characterize steppe soil changes by irrigated agriculture, we analyzed the enzymatic activities involved in the biogeochemical cycles (carbon, nitrogen, phosphorus and sulfur), the whole soil fatty acids profile, the state of soil aggregation, and the bacterial and fungal microbiota through DNA sequencing methods. …”