Incomplete Albumin-Cre-mediated deletion of <i>Rps6</i> results in mosaicism for RPS6 expression across the neonatal liver. by Sarah A. Comerford (3854917)

“…After stripping, the blot was incubated with a p³²-radiolabeled 18S rRNA probe. (D) Graph showing quantitation of the Northern blot shown in (C) demonstrating that <i>Rps6</i> mRNA levels are decreased by 50–60% in ΔS6 livers relative to WT. …”

Datasheet1_Comparative effectiveness of standard vs. AI-assisted PET/CT reading workflow for pre-treatment lymphoma staging: a multi-institutional reader study evaluation.pdf by Russell Frood (8485714)

“…</p>Results<p>There was a significant decrease in time between non-AI and AI-assisted reads (median 15.0 vs. 13.3 min, p < 0.001). …”

Data Sheet 1_Host-specific vascular endothelial cell responses to Angiostrongylus vasorum: a comparative in vitro study in red foxes (Vulpes vulpes) and domestic dogs.docx by Belinda Eisenhut (21466943)

“…</p>Discussion<p>These findings corroborate that foxes have developed mechanisms for a regulated immune response following A. vasorum exposure, while dogs exhibit a higher pro-inflammatory reaction, contributing to severe clinical outcomes. …”

Differential antibody and cytokine responses associated with resistance to <i>T. cruzi</i>. by Marianne A. Bryan (246141)

“…<p>These plots model responses in <i>T. cruzi</i> infected C57Bl/6 and Balb/c mice compared to control mice inoculated with heat-inactivated parasite (original data in <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000733#pntd-0000733-g001" target="_blank">Fig 1</a>–<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000733#pntd-0000733-g002" target="_blank"></a><a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000733#pntd-0000733-g003" target="_blank"></a><a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000733#pntd-0000733-g004" target="_blank"></a><a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000733#pntd-0000733-g005" target="_blank">5</a>) and show the association of parasite-specific antibody responses in the blood and spleen with decreased polyclonal antibody responses and differential cytokine expression (kinetics and quality summarized here). …”

DataSheet_1_Safety and Efficacy of Sintilimab and Anlotinib as First Line Treatment for Advanced Hepatocellular Carcinoma (KEEP-G04): A Single-Arm Phase 2 Study.docx by Xiaofeng Chen (392939)

“…Grade 3 TRAEs occurred in 8 (40.0%) patients, the most common being decreased platelet count (10.0%) and increased γ-glutamyl transferase (10.0%). …”

Time-dependent effects of NE/IFN-γ on MHC-I (A), B7-1 (B), IDO (C) and B7-H1 (D) mRNA expression. by Liancai Wang (306725)

DataSheet_1_A Novel Glucocorticoid and Androgen Receptor Modulator Reduces Viral Entry and Innate Immune Inflammatory Responses in the Syrian Hamster Model of SARS-CoV-2 Infection.... by Savannah M. Rocha (10826524)

“…Results indicated that oral administration of PT150 caused a dose-dependent decrease in replication of SARS-CoV-2 in lung, as well as in expression of ACE2 and TMPRSS2. …”

NSAIDs do not prevent the increase in [Ca²⁺]_cyt induced by Aβ_1–42- oligomers or affect cell ATP levels. by Sara Sanz-Blasco (271498)

“…<i>H</i>. Salicylate 100 µM increased [Ca²⁺]_cyt further in cells treated with Aβ_25–35 (20 µM). …”

Data Sheet 1_Global burden, trends and inequalities of maternal hypertensive disorders among reproductive-age women of advanced maternal age, 1990–2021: a population-based study.pd... by Xuanyu Zhao (5881895)

“…</p>Methods<p>We conducted a population-based study using data from the Global Burden of Disease (GBD) 2021 study, covering 204 countries and territories. …”

Supplementary Material for: A Lentiviral CXCR4 Overexpression and Knockdown Model in Colorectal Cancer Cell Lines Reveals Plerixafor-Dependent Suppression of SDF-1α-Induced Migrati... by Heckmann D. (4129651)

“…Functional CXCR4 knockdown using lentiviral short hairpin RNA (shRNA) vectors significantly decreased the migration behavior in CRC cell lines (p < 0.001), confirming a CXCR4-specific effect. …”

DataSheet3_Red Yeast Rice Preparations Reduce Mortality, Major Cardiovascular Adverse Events, and Risk Factors for Metabolic Syndrome: A Systematic Review and Meta−analysis.docx by Rong Yuan (2526103)

“…Regarding blood pressure, the mean arterial pressure (MAP) (MD = −3.79 mmHg, 95% CI [−5.01, −2.57]) was decreased. …”

DataSheet2_Red Yeast Rice Preparations Reduce Mortality, Major Cardiovascular Adverse Events, and Risk Factors for Metabolic Syndrome: A Systematic Review and Meta−analysis.docx by Rong Yuan (2526103)

“…Regarding blood pressure, the mean arterial pressure (MAP) (MD = −3.79 mmHg, 95% CI [−5.01, −2.57]) was decreased. …”

DataSheet1_Red Yeast Rice Preparations Reduce Mortality, Major Cardiovascular Adverse Events, and Risk Factors for Metabolic Syndrome: A Systematic Review and Meta−analysis.docx by Rong Yuan (2526103)

“…Regarding blood pressure, the mean arterial pressure (MAP) (MD = −3.79 mmHg, 95% CI [−5.01, −2.57]) was decreased. …”

Neuronal responses to visual stimuli in the proposed microcircuit model with different excitatory/inhibitory (E/I) ratios caused by a change in pyramidal (Pyr) neuron and somatosta... by Nobuhiko Wagatsuma (494052)

“…<b><i>A.</i></b> Mean population firing rates of Pyr (first panel from the left), parvalbumin (PV; second panel), SOM (third panel), and vasoactive intestinal polypeptide (VIP; fourth panel) populations as a function of E/I ratios. …”

Data_Sheet_1_One-Year Change in the H2FPEF Score After Catheter Ablation of Atrial Fibrillation in Patients With a Normal Left Ventricular Systolic Function.pdf by Min Kim (218786)

“…Baseline high H₂FPEF scores (≥6) were independently associated with the female sex, left atrium (LA) diameter, LV mass index, pericardial fat volume, and a low estimated glomerular filtration rate. One year after AFCA, decreased ΔH₂FPEF scores_[1−yr] were associated with baseline H₂FPEF scores of ≥6 [OR, 4.19 (95% CI, 2.88–6.11), p < 0.001], no diabetes [OR, 0.60 (95% CI, 0.37–0.98), p = 0.04], and lower pericardial fat volume [OR, 0.99 (95% CI, 0.99–1.00), p = 0.003]. …”

Image2_Utilizing multimodal mass spectrometry imaging for profiling immune cell composition and N-glycosylation across colorectal carcinoma disease progression.TIFF by Lyndsay E. A. Young (6329558)

“…We detected nearly 100 N-glycan species across all samples, revealing a shift in N-glycome profiles from normal to cancerous tissues, marked by a decrease in high mannose N-glycans. …”

Image1_Utilizing multimodal mass spectrometry imaging for profiling immune cell composition and N-glycosylation across colorectal carcinoma disease progression.TIFF by Lyndsay E. A. Young (6329558)

“…We detected nearly 100 N-glycan species across all samples, revealing a shift in N-glycome profiles from normal to cancerous tissues, marked by a decrease in high mannose N-glycans. …”

Table1_Utilizing multimodal mass spectrometry imaging for profiling immune cell composition and N-glycosylation across colorectal carcinoma disease progression.XLSX by Lyndsay E. A. Young (6329558)

“…We detected nearly 100 N-glycan species across all samples, revealing a shift in N-glycome profiles from normal to cancerous tissues, marked by a decrease in high mannose N-glycans. …”

Image6_Utilizing multimodal mass spectrometry imaging for profiling immune cell composition and N-glycosylation across colorectal carcinoma disease progression.TIFF by Lyndsay E. A. Young (6329558)

“…We detected nearly 100 N-glycan species across all samples, revealing a shift in N-glycome profiles from normal to cancerous tissues, marked by a decrease in high mannose N-glycans. …”

Image5_Utilizing multimodal mass spectrometry imaging for profiling immune cell composition and N-glycosylation across colorectal carcinoma disease progression.TIFF by Lyndsay E. A. Young (6329558)

“…We detected nearly 100 N-glycan species across all samples, revealing a shift in N-glycome profiles from normal to cancerous tissues, marked by a decrease in high mannose N-glycans. …”