FIGURE 4 from D-2-HG Inhibits <i>IDH1^mut</i> Glioma Growth via FTO Inhibition and Resultant m6A Hypermethylation by Sean T. Pianka (18237413)

“…<p>FTO inhibition attenuates gliomasphere growth. <b>A,</b> Increase in U87 RNA m6A content relative to control (0 µmol/L) following the application of FTO inhibitors FB23-2 (left) or MA (right) at various doses. …”

Effects of Tbx5 Paralogues on the Somites. by Erin A. T. Boyle Anderson (6065756)

“…Both Tbx5b-deficient and double-deficient embryos showed a significant decrease in somite size compared to wt embryos. …”

Data Sheet 1_Deciphering a missing piece of the branched-chain amino acids uptake puzzle: YhjE is an L-isoleucine and L-valine transporter in Escherichia coli K-12.docx by Sergey V. Molev (22769330)

“…<p>Branched-chain amino acid (BCAA) uptake in bacteria underpins fitness, pathogenesis, and industrial strain performance, yet the transport landscape, even in Escherichia coli, remains incomplete. Here, we identify and characterize YhjE as a BCAA permease specific for L-isoleucine and L-valine. …”

The basic flowchart of analysis in this study. by Jing Wang (6206297)

“…</p><p>Results</p><p>19 DECAGs were found in AD and the key biological processes and molecular functions associated with AD were further determined. Two subtypes of peripheral blood cells showed significant alternations in AD: Cluster1 and Cluster2. …”

The enriched GO terms of the 19 DECAGs. by Jing Wang (6206297)

“…</p><p>Results</p><p>19 DECAGs were found in AD and the key biological processes and molecular functions associated with AD were further determined. Two subtypes of peripheral blood cells showed significant alternations in AD: Cluster1 and Cluster2. …”

Primers of the tested genes. by Jing Wang (6206297)

“…</p><p>Results</p><p>19 DECAGs were found in AD and the key biological processes and molecular functions associated with AD were further determined. Two subtypes of peripheral blood cells showed significant alternations in AD: Cluster1 and Cluster2. …”

Summary of patient demographic characteristics. by Jing Wang (6206297)

“…</p><p>Results</p><p>19 DECAGs were found in AD and the key biological processes and molecular functions associated with AD were further determined. Two subtypes of peripheral blood cells showed significant alternations in AD: Cluster1 and Cluster2. …”

Table 1_The evolution of the global disease burden of polycystic ovary syndrome and the role of regional heterogeneity in high body mass index exposure: a spatiotemporal analysis b... by Ying Feng (151159)

“…</p>Results<p>In 2021, the global age-standardized prevalence rate (ASPR) of PCOS was 867.7 per 100,000 [95% UI: 618.7–1,195.3], representing a significant increase of 0.75 compared with 1990 [95% CI: 0.71–0.78]. …”

Modelling local immune dynamics during HPV infections. by Nicolas Tessandier (20355027)

“…(B) Illustration of the additional steps for the FCM model. We consider the same two virus genotypes <i>A</i> and <i>B</i> and two hypothetical cell populations: 1, whose trajectory computation is illustrated in panel A, and 2, generated in the same way, with the same <i>t</i>_start, and <i>t</i>_clear, but different <i>ψ</i>s. …”

Data_Sheet_1_Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR.ZIP by Yamina El Hamdaoui (6759080)

“…Two-electrode voltage clamp analysis on oocyte-expressed nAChR subtypes demonstrated the functionality of these peptides but also revealed a 30 to 100-fold potency decrease of expressed TxIA compared to chemically synthesized TxIA. …”

IFT88 shRNA shortens cilia and enhances RGC degeneration following ONT. by Brian K. A. Choi (7114916)

“…(D) Representative epifluorescence micrographs of RBPMS immunolabeled RGCs in the inner eccentricity of flatmounted retinas at 7 days post-ONT, expressing control shRNA (top) or IFT88 shRNA (bottom). Scale bar = 100 μm. (E) Quantification of RGCs showing that IFT88 shRNA expression significantly decrease RGC survival at 7 days post ONT, relative to scrambled control hairpin. …”

Gene expression of <i>Iex-1</i> and <i>Vegf-A</i> by qRT-PCR in outflow vein of AVF seven days after adventitial delivery of hydrogel alone, hydrogel with nanoparticle PLGA without... by Akshaar Brahmbhatt (551498)

“…This demonstrates a significant decrease in the mean <i>Iex-1</i> expression in nanoparticle coated with calcitriol compared to PLGA (P<0.05). …”

Data Sheet 1_Global, regional and national burden of decubitus ulcers in 204 countries and territories from 1990 to 2021: a systematic analysis based on the global burden of diseas... by Shenyue Zhang (18472266)

“…The global ASR of prevalence decreased slightly from 8.25 to 7.92 per 100,000 persons, with most cases occurring in individuals aged 60 and older. …”

Incidence of self-reported tuberculosis treatment with community-wide universal testing and treatment for HIV and tuberculosis screening in Zambia and South Africa: A planned analy... by L. Telisinghe (18706323)

“…There was also some evidence this translated to a decrease in self-reported TB incidence overall in the population. …”

Kidneys from Kif5b-Pax2KD (<i>Kif5bfl/-</i>:<i>Pax2-Cre</i>) embryos have a reduced cell proliferation rate. by Ju Cui (726069)

“…<p>(A) <i>In situ</i> analysis of BrdU incorporation at E18.5. …”

Table 1_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for the... by Shen Tian (4424170)

“…Between 1990 and 2021, the global age-standardized mortality rate (ASDR) decreased from 15.6 to 12.4 per 100,000, and the age-standardized DALY rate declined from 357.3 to 283.2 per 100,000. …”

Data_Sheet_2_Medication Non-adherence and Condomless Anal Intercourse Increased Substantially During the COVID-19 Pandemic Among MSM PrEP Users: A Retrospective Cohort Study in Fou... by Yangyang Gao (1602409)

“…The proportion of those who were tested for HIV decreased from 50.1 to 25.9%. Factors correlated with poor PrEP adherence during the COVID-19 included not being tested for HIV (adjusted odds ratio [aOR] = 1.38 [95% CI: 1.00, 1.91]), using condoms consistently with regular partners (vs. never, aOR = 2.19 [95% CI: 1.16, 4.13]), and being married or cohabitating with a woman (vs. not married, aOR = 3.08 [95% CI: 1.60, 5.95]).…”

Data_Sheet_1_Medication Non-adherence and Condomless Anal Intercourse Increased Substantially During the COVID-19 Pandemic Among MSM PrEP Users: A Retrospective Cohort Study in Fou... by Yangyang Gao (1602409)

“…The proportion of those who were tested for HIV decreased from 50.1 to 25.9%. Factors correlated with poor PrEP adherence during the COVID-19 included not being tested for HIV (adjusted odds ratio [aOR] = 1.38 [95% CI: 1.00, 1.91]), using condoms consistently with regular partners (vs. never, aOR = 2.19 [95% CI: 1.16, 4.13]), and being married or cohabitating with a woman (vs. not married, aOR = 3.08 [95% CI: 1.60, 5.95]).…”

Data_Sheet_3_Medication Non-adherence and Condomless Anal Intercourse Increased Substantially During the COVID-19 Pandemic Among MSM PrEP Users: A Retrospective Cohort Study in Fou... by Yangyang Gao (1602409)

“…The proportion of those who were tested for HIV decreased from 50.1 to 25.9%. Factors correlated with poor PrEP adherence during the COVID-19 included not being tested for HIV (adjusted odds ratio [aOR] = 1.38 [95% CI: 1.00, 1.91]), using condoms consistently with regular partners (vs. never, aOR = 2.19 [95% CI: 1.16, 4.13]), and being married or cohabitating with a woman (vs. not married, aOR = 3.08 [95% CI: 1.60, 5.95]).…”

Data_Sheet_1_Developmental Effects on Auditory Neural Oscillatory Synchronization Abnormalities in Autism Spectrum Disorder.docx by Lisa A. De Stefano (7040126)

“…Fifteen participants with ASD (3 female, aged 6–23 years) and 15 age-matched controls (4 female, aged 6–25 years) underwent dense-array EEG as they listened to a carrier tone amplitude-modulated by a sinusoid linearly increasing in frequency from 0–100 Hz over 2 s. …”