Evidence for Substrate Preorganization in the Peptidylglycine α-Amidating Monooxygenase Reaction Describing the Contribution of Ground State Structure to Hydrogen Tunneling by Neil R. McIntyre (2249155)

“…The first step, the copper-, ascorbate-, and O₂-dependent stereospecific hydroxylation at the α-carbon of the C-terminal glycine, is catalyzed by peptidylglycine α-hydroxylating monooxygenase (PHM). …”

Point-of-care testing for <i>Toxoplasma gondii</i> IgG/IgM using <i>Toxoplasma</i> ICT IgG-IgM test with sera from the United States and implications for developing countries by Ian J. Begeman (4172935)

“…</p><p>Results</p><p>We found that this new <i>Toxoplasma</i> ICT IgG-IgM POC test was highly sensitive (100%) and specific (100%) for distinguishing IgG/IgM-positive from negative sera. …”

Video2_TIMP3 induces gene expression partly through PI3K and their association with vascularization and heart rate.mp4 by Zi-Meng Xia (14847547)

“…Background<p>Tissue inhibitor of metalloproteinase 3 (TIMP3) was recently demonstrated capable to regulate some gene expression in a myocardial infarction model. Here we aim to explore the gene expression profile in TIMP3-treated cardiomyocytes and related potential cardiovascular functions.…”

Datasheet1_TIMP3 induces gene expression partly through PI3K and their association with vascularization and heart rate.pdf by Zi-Meng Xia (14847547)

“…Background<p>Tissue inhibitor of metalloproteinase 3 (TIMP3) was recently demonstrated capable to regulate some gene expression in a myocardial infarction model. Here we aim to explore the gene expression profile in TIMP3-treated cardiomyocytes and related potential cardiovascular functions.…”

Video1_TIMP3 induces gene expression partly through PI3K and their association with vascularization and heart rate.mp4 by Zi-Meng Xia (14847547)

“…Background<p>Tissue inhibitor of metalloproteinase 3 (TIMP3) was recently demonstrated capable to regulate some gene expression in a myocardial infarction model. Here we aim to explore the gene expression profile in TIMP3-treated cardiomyocytes and related potential cardiovascular functions.…”

Detecting and Destroying Cancer Cells in More than One Way with Noble Metals and Different Confinement Properties on the Nanoscale by Erik C. Dreaden (1316589)

“…However, as improved detection and increasing exposure to carcinogens has led to higher rates of cancer incidence, clinicians and researchers have not balanced that increase with a similar decrease in cancer mortality rates. This mismatch highlights a clear and urgent need for increasingly potent and selective methods with which to detect and treat cancers at their earliest stages.Nanotechnology, the use of materials with structural features ranging from 1 to 100 nm in size, has dramatically altered the design, use, and delivery of cancer diagnostic and therapeutic agents. …”

Detecting and Destroying Cancer Cells in More than One Way with Noble Metals and Different Confinement Properties on the Nanoscale by Erik C. Dreaden (1316589)

“…However, as improved detection and increasing exposure to carcinogens has led to higher rates of cancer incidence, clinicians and researchers have not balanced that increase with a similar decrease in cancer mortality rates. This mismatch highlights a clear and urgent need for increasingly potent and selective methods with which to detect and treat cancers at their earliest stages.Nanotechnology, the use of materials with structural features ranging from 1 to 100 nm in size, has dramatically altered the design, use, and delivery of cancer diagnostic and therapeutic agents. …”

Supporting data for "Excess mortality during the COVID-19 pandemic in Hong Kong and South Korea" by Shuqi Xu (12992556)

“…Mortality from influenza and pneumonia was estimated to have a statistically significant increase in HK but a decrease in SK probability due to different coding practices. …”

Image5_The effect of ginger extract on cisplatin-induced acute anorexia in rats.TIFF by Hyeonah Kim (17359114)

“…Among these, acute anorexia is one of the most severe secondary effects. In this study, a single oral administration of 100 or 500 mg/kg ginger extract (GE) significantly alleviated the cisplatin-induced decrease in food intake in rats. …”

Image1_The effect of ginger extract on cisplatin-induced acute anorexia in rats.TIF by Hyeonah Kim (17359114)

“…Among these, acute anorexia is one of the most severe secondary effects. In this study, a single oral administration of 100 or 500 mg/kg ginger extract (GE) significantly alleviated the cisplatin-induced decrease in food intake in rats. …”

Image2_The effect of ginger extract on cisplatin-induced acute anorexia in rats.TIF by Hyeonah Kim (17359114)

“…Among these, acute anorexia is one of the most severe secondary effects. In this study, a single oral administration of 100 or 500 mg/kg ginger extract (GE) significantly alleviated the cisplatin-induced decrease in food intake in rats. …”

Image4_The effect of ginger extract on cisplatin-induced acute anorexia in rats.TIFF by Hyeonah Kim (17359114)

“…Among these, acute anorexia is one of the most severe secondary effects. In this study, a single oral administration of 100 or 500 mg/kg ginger extract (GE) significantly alleviated the cisplatin-induced decrease in food intake in rats. …”

Image6_The effect of ginger extract on cisplatin-induced acute anorexia in rats.TIFF by Hyeonah Kim (17359114)

“…Among these, acute anorexia is one of the most severe secondary effects. In this study, a single oral administration of 100 or 500 mg/kg ginger extract (GE) significantly alleviated the cisplatin-induced decrease in food intake in rats. …”

Image3_The effect of ginger extract on cisplatin-induced acute anorexia in rats.TIF by Hyeonah Kim (17359114)

“…Among these, acute anorexia is one of the most severe secondary effects. In this study, a single oral administration of 100 or 500 mg/kg ginger extract (GE) significantly alleviated the cisplatin-induced decrease in food intake in rats. …”

Synaptic efficacy is reduced during UP states. by Brendon O. Watson (268774)

“…Every neuron examined (n = 16) showed a decrease in depolarization from baseline (population mean was a 103.3% decrease, standard deviation 14.1%). …”

Table_1_Increasing Number of Individuals Receiving Hepatitis B nucleos(t)ide Analogs Therapy in Germany, 2008–2019.DOCX by Anna Maisa (263303)

“…Contrary to guideline recommendation, adefovir was still prescribed after 2011 for 1–5% of patients albeit with decreasing tendency. Prescriptions per 100,000 inhabitants were highest in Berlin and Hamburg.…”

Table_1_Increasing Number of Individuals Receiving Hepatitis B nucleos(t)ide Analogs Therapy in Germany, 2008–2019.DOCX by Anna Maisa (263303)

“…Contrary to guideline recommendation, adefovir was still prescribed after 2011 for 1–5% of patients albeit with decreasing tendency. Prescriptions per 100,000 inhabitants were highest in Berlin and Hamburg.…”

Low Socioeconomic Status Is Associated with Prolonged Times to Assessment and Treatment, Sepsis and Infectious Death in Pediatric Fever in El Salvador by Ronald Gavidia (141156)

“…Providing additional education to high-risk families and staying at a nearby guest house during periods of neutropenia may decrease sepsis and infectious mortality.…”

fon-2021-1437_suppl_data by Charles Peterfy (674120)

“…From baseline to last visit, 94% of patients (29/31) showed a decrease in tumor size (median change: −60% [RECIST], −66% [m-RECIST], −79% [TVS]). …”

Updated Emission Factors from Diffuse Combustion Sources in Sub-Saharan Africa and Their Effect on Regional Emission Estimates by David J. Pfotenhauer (6708245)

“…Large differences are calculated for all updated source emissions, showing a 96% increase in OC and 78% decrease in EC compared to prior estimates for Ghana’s emissions. …”