Data_Sheet_1_Alaska Volcano Observatory Alert and Forecasting Timeliness: 1989–2017.xlsx by Cheryl E. Cameron (5477414)

“…For remote volcanoes where the main hazard is to aviation, rapid detection is a goal in the absence of in situ monitoring. Eruption detection has improved in recent years, shown by a decrease in the time between eruption onset and notification. …”

Overexpression or silencing of the mu opioid receptor (MOR) or addition of opioids in human lung cancer cells regulates epithelial mesenchymal transition (EMT). by Frances E. Lennon (541593)

“…An increase in vimentin, Snail and Slug expression and a decrease in claudin-1 and ZO-1 expression suggest an epithelial mesenchymal transition. …”

Table 1_Global, regional, national epidemiology and trends of Parkinson’s disease from 1990 to 2021: findings from the Global Burden of Disease Study 2021.docx by Yuanrong Luo (20539082)

“…Age-standardized rates of incidence, prevalence, and DALYs increased to 15.63/100,000, 138.63/100,000, and 89.59/100,000. The burden of Parkinson’s disease were higher in males than in females, and showed an increase and then a slight decrease with age. …”

RI-OR2-TAT reduces the brain load of microglia and oxidative damage and stimulates neurogenesis in APP/PS1 transgenic mice. by Vadivel Parthsarathy (285723)

“…<p>Representative images of activated microglia in the cortical region of APP/PS1 mouse brains as shown by Iba1 immunostaining in animals treated with (<b>A</b>) 0.9% saline or (<b>B</b>) 100 nmol/kg RI-OR2-TAT in 0.9% saline; (<b>C</b>) quantitative analysis shows a decrease in mean microglial load in APP/PS1 mice treated with RI-OR2-TAT; detection of 8 oxo-guanine in the brains of animals treated with (<b>D</b>) 0.9% saline or (<b>E</b>) 100 nmol/kg RI-OR2-TAT; (<b>F</b>) quantitative analysis shows a decrease in mean 8 oxo-guanine staining in APP/PS1 mice treated with RI-OR2-TAT; detection of immature neurons as stained for doublecortin in the dentate gyrus of APP/PS1 mice treated with (<b>G</b>) 0.9% saline or (<b>H</b>) 100 nmol/kg RI-OR2-TAT; (<b>I</b>) quantitative analysis shows an increase in mean doublecortin staining in APP/PS1 mice treated with RI-OR2-TAT. …”

Potential mechanisms. by Iwan Zimmermann (117942)

“…Channel gating (described by the efficacy equilibrium constant <i>E</i>) is impaired when the channel is bound to divalent ions (yellow circles, <i>E</i>_Ca²⁺). The decrease in agonist efficacy is likely to be due to a change in the rate of opening, as shown by the size of the arrows in the last step of the reaction. …”

Data from: Viviparity does not affect the numbers and sizes of reptile offspring by Shai Meiri (394933)

“…However, our phylogenetically-controlled analysis of data on 1,259 squamate species revealed no significant differences in mean offspring size, clutch size or RI between oviparous and viviparous squamates. We attribute this paradoxical result to (1) strong selection on optimal offspring sizes, unaffected by parity mode, (2) the lack of a larval stage in amniotes, favouring large eggs even in the ancestral oviparous mode, and (3) the ability of viviparous females to decrease the mass of uterine embryos by reducing extra-embryonic water stores. …”

E2F6 Impairs Glycolysis and Activates BDH1 Expression Prior to Dilated Cardiomyopathy by Jennifer L. Major (3639472)

“…Using the Seahorse platform, a 22% decrease in glycolysis was noted in neonatal cardiomyocytes isolated from E2F6-Tg hearts. …”

Data_Sheet_1_Carbon on the Northwest European Shelf: Contemporary Budget and Future Influences.PDF by Oliver Legge (8591469)

“…Benthic carbon stocks will be affected by increasing temperature and acidity, and decreasing oxygen concentrations, although the net impact of these interrelated changes on carbon stocks is uncertain and a major knowledge gap. …”

Mathematical model predictions of the detyrosination inhibition with experimental validation in proliferative cells. by Jeremy Grignard (12963351)

“…The BIOCHAM commands used are: change_parameter_to_variable(k1), dose_response(k1, 0, 10, time:100, show:TyrDetyr). The BIOCHAM command draws a dose-response diagram by linear variation of the initial concentration (the dose) of the input object, here <i>k</i>₁, and plotting the output object (the response), here the molecular species: Tyr, Detyr and TyrDetyr, showing an increase of the tyrosination status with a decrease of <i>k</i>₁. …”

Assessment of sesquiterpene lactones isolated from <i>Mikania</i> plants species for their potential efficacy against <i>Trypanosoma cruzi</i> and <i>Leishmania</i> sp. by Laura C. Laurella (469416)

“…More importantly, while 100% of control mice died by day 22 after receiving a lethal <i>T</i>. …”

DataSheet_2_The transcriptome response of astronaut leukocytes to long missions aboard the International Space Station reveals immune modulation.pdf by Daniel Stratis (16415880)

“…Interestingly, 100 genes were both downregulated when reaching space and upregulated when landing on Earth. …”

DataSheet_3_The transcriptome response of astronaut leukocytes to long missions aboard the International Space Station reveals immune modulation.pdf by Daniel Stratis (16415880)

“…Interestingly, 100 genes were both downregulated when reaching space and upregulated when landing on Earth. …”

DataSheet_4_The transcriptome response of astronaut leukocytes to long missions aboard the International Space Station reveals immune modulation.pdf by Daniel Stratis (16415880)

“…Interestingly, 100 genes were both downregulated when reaching space and upregulated when landing on Earth. …”

DataSheet_1_The transcriptome response of astronaut leukocytes to long missions aboard the International Space Station reveals immune modulation.pdf by Daniel Stratis (16415880)

“…Interestingly, 100 genes were both downregulated when reaching space and upregulated when landing on Earth. …”

Table_1_The transcriptome response of astronaut leukocytes to long missions aboard the International Space Station reveals immune modulation.docx by Daniel Stratis (16415880)

“…Interestingly, 100 genes were both downregulated when reaching space and upregulated when landing on Earth. …”

ndrg4 function is required for the expression of several genes that are essential for vesicle docking. by Laura Fontenas (3371204)

“…<p>(A) qPCR showing a significant decrease in the expression of nsfa, syt1a, stxbp1b but not vamp2 in ndrg4 mutants with mRNA relative expression to ef1a. …”

Ca²⁺ induced swelling in isolated mitochondria. by Jun Li (6494)

“…<p>(<b>A</b>) Representative traces of 100–1000 µmol/L Ca²⁺ induced a decrease in light transmission in the ischemia/reperfusion (I/R) 24 h group. …”

S1 Data - by Ranjeeta Adhikari (9905958)

“…Statistical comparisons between tolerant and sensitive cultivars in the N-deficient treatment indicated an increase in shoot biomass (19.9 vs 14.4 g), leaf area (2775 vs 1824 cm²), leaf dry weight (14.7 vs 10.0 g), lateral root dry weight (3.7 vs 2.4 g), light-saturated photosynthesis (14.5 vs 10.1 μmol∙m^-2∙s^-1), maximum electron transport rate (119 vs 89 μmol∙m^-2∙s^-1), chlorophyll content (28.1 vs 12.9 g∙100g^-1), leaf N content (27.5 vs 19.9 mg∙g^-1), and fine root N content (26.1 vs 20.9 mg∙g^-1), and a decrease in anthocyanin content (0.07 vs 0.16 ΔOD∙g^-1). …”

Yolk sac erythropoiesis is impaired in Actb−/− embryos. by Davina Tondeleir (426905)

“…<p>(A) Primitive erythroid colonies (EryP) from E8.5 yolk sacs measured by methylcellulose assays show a dramatic decrease in colony forming potential in <i>Actb^−/−</i> embryos compared to <i>Actb^+/+</i> embryos. …”

Animation 1 by Vina Putra (20363598)

“…Previous studies showed that this compression results in both a decrease in cell volume as well as a change in the shape of the nucleus (shape shift due to compression)​11​. …”