Showing 441 - 460 results of 103,558 for search '(( 2 step decrease ) OR ( 5 ((((mean decrease) OR (point decrease))) OR (a decrease)) ))', query time: 1.80s Refine Results
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    PKCε activation induces aggrecan gene expression, decreases ADAMTS5, and detection of ADAMTS-5-depended cleavage of ECM aggrecan through upregulation of hsa-miR-377 expression. by Emmanouella Tsirimonaki (490707)

    Published 2013
    “…<p>(<b>A</b>) RT-PCR detected the relative expression of ACAN, MKI67, ADAMTS5 after treatment of NP cells with 1 μM ψεRACK (or vehicle) for indicated times and revealed that time-dependent activation of PKCε significantly increased the mRNA expression for aggrecan, while in an opposing manner decreased ADAMTS5; mRNA levels of the proliferation marker Ki67 became barely detectable after 8 hours of PKCε activation. …”
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