Showing 1,461 - 1,480 results of 102,069 for search '(( 2 step decrease ) OR ( 5 ((((mg decrease) OR (a decrease))) OR (nn decrease)) ))', query time: 1.64s Refine Results
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    Target specificity, <i>in vivo</i> pharmacokinetics, and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma by Peter Y. Yu (4281448)

    Published 2017
    “…The purpose of this work was to develop and test a novel putative STAT3 inhibitor, LY5.</p><p>Methods and findings</p><p>An <i>in silico</i> fragment-based drug design strategy was used to create LY5, a small molecule inhibitor that blocks the STAT3 SH2 domain phosphotyrosine binding site, inhibiting homodimerization. …”
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    ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of γ-secretase activity-5 by Rodrigo A Fuentealba (77901)

    Published 2011
    “…<p><b>Copyright information:</b></p><p>Taken from "ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of γ-secretase activity"</p><p>http://www.molecularneurodegeneration.com/content/2/1/14</p><p>Molecular Neurodegeneration 2007;2():14-14.…”
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    Flibanserin’s neuroprotective effects are 5-HT<sub>1A</sub> receptor-mediated. by Aaron S. Coyner (2889722)

    Published 2016
    “…<p>(<b>A i</b>) A spider graph representing average right-eye receptor plus values demonstrates that pre-treatment with WAY 100635 prior to 6 mg/kg flibanserin (10 mg/kg WAY + 6 mg/kg Flibanserin, <i>green</i>) decreased average receptor plus thickness as compared to flibanserin-treatment without WAY 100635 (6 mg/kg Flibanserin, <i>blue</i>). …”
  16. 1476

    Structural and Co-conformational Effects of Alkyne-Derived Subunits in Charged Donor−Acceptor [2]Catenanes by Ognjen Š. Miljanić (2485972)

    Published 2007
    “…Four donor−acceptor [2]catenanes with cyclobis(paraquat-<i>p</i>-phenylene) (CBPQT<sup>4+</sup>) as the π-electron-accepting cyclophane and 1,5-dioxynaphthalene (DNP)-containing macrocyclic polyethers as π-electron donor rings have been synthesized under mild conditions, employing Cu<sup>+</sup>-catalyzed Huisgen 1,3-dipolar cycloaddition and Cu<sup>2+</sup>-mediated Eglinton coupling in the final steps of their syntheses. …”
  17. 1477

    Structural and Co-conformational Effects of Alkyne-Derived Subunits in Charged Donor−Acceptor [2]Catenanes by Ognjen Š. Miljanić (2485972)

    Published 2007
    “…Four donor−acceptor [2]catenanes with cyclobis(paraquat-<i>p</i>-phenylene) (CBPQT<sup>4+</sup>) as the π-electron-accepting cyclophane and 1,5-dioxynaphthalene (DNP)-containing macrocyclic polyethers as π-electron donor rings have been synthesized under mild conditions, employing Cu<sup>+</sup>-catalyzed Huisgen 1,3-dipolar cycloaddition and Cu<sup>2+</sup>-mediated Eglinton coupling in the final steps of their syntheses. …”
  18. 1478

    Structural and Co-conformational Effects of Alkyne-Derived Subunits in Charged Donor−Acceptor [2]Catenanes by Ognjen Š. Miljanić (2485972)

    Published 2007
    “…Four donor−acceptor [2]catenanes with cyclobis(paraquat-<i>p</i>-phenylene) (CBPQT<sup>4+</sup>) as the π-electron-accepting cyclophane and 1,5-dioxynaphthalene (DNP)-containing macrocyclic polyethers as π-electron donor rings have been synthesized under mild conditions, employing Cu<sup>+</sup>-catalyzed Huisgen 1,3-dipolar cycloaddition and Cu<sup>2+</sup>-mediated Eglinton coupling in the final steps of their syntheses. …”
  19. 1479

    Structural and Co-conformational Effects of Alkyne-Derived Subunits in Charged Donor−Acceptor [2]Catenanes by Ognjen Š. Miljanić (2485972)

    Published 2007
    “…Four donor−acceptor [2]catenanes with cyclobis(paraquat-<i>p</i>-phenylene) (CBPQT<sup>4+</sup>) as the π-electron-accepting cyclophane and 1,5-dioxynaphthalene (DNP)-containing macrocyclic polyethers as π-electron donor rings have been synthesized under mild conditions, employing Cu<sup>+</sup>-catalyzed Huisgen 1,3-dipolar cycloaddition and Cu<sup>2+</sup>-mediated Eglinton coupling in the final steps of their syntheses. …”
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