Showing 13,981 - 14,000 results of 101,662 for search '(( 2 step decrease ) OR ( 5 ((((ng decrease) OR (a decrease))) OR (nn decrease)) ))', query time: 1.51s Refine Results
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    Figure 5, supplementary figure 7 by Kristen Pleil (11084931)

    Published 2024
    “…</b>a-d) Analysis of single nucleus RNA sequencing of female BNST nuclei (total cells: 38,806; GEO: GSE126836)<sup>78</sup>. a) <i>Crh</i> (CRF) expression (7.7%) in female BNST cells. b) <i>Slc117a6</i> (VGLUT2) expression (7.6%) in female BNST cells. c) <i>Gfap</i> (GFAP) expression (0.7%) in female BNST cells. d) ERα (27%) and ERβ (9%) expression (5% both) in female BNST<sup>GFAP</sup> cells. e-f) Effects of acute bath application of the ERα antagonist methyl-piperidino-pyrazole (MPP) on excitatory synaptic transmission in BNST<sup>CRF</sup> neurons during whole-cell slice electrophysiology recordings in high ovarian E2 female CRF-CrexAi9 reporter mice, as depicted in e. f) Time course of high E2 status BNST<sup>CRF</sup> neurons that displayed an increase, decrease, or variable change in spontaneous excitatory postsynaptic current (sEPSC) frequency (left) and amplitude (right) % change from baseline during the 5-minute MPP wash on application period and 5 minute washout. g-i) Effects of acute bath application of MPP on excitatory synaptic transmission in BNST<sup>CRF</sup> neurons during whole-cell slice electrophysiology recordings in low ovarian E2 female CRF-CrexAi9 reporter mice, as depicted in g. f) Time course of low E2 status BNST<sup>CRF</sup> neurons that displayed an increase, decrease, or variable change in spontaneous excitatory postsynaptic current (sEPSC) frequency (left) and amplitude (right) % change from baseline during the 5-minute MPP wash on application period and 5 minute washout. i) Bath application of MPP (3 μM) had no effect on spontaneous excitatory postsynaptic current (sEPSC) frequency (left) and amplitude (right) in a majority of cells during the 5 min wash on period (Ns = 3 mice, 7 cells). j) Depiction of strategy to site-deliver MPP (10 μM/200 nl/side or saline vehicle (VEH) to the BNST in low E2 females via bilateral indwelling cannulae 10 minutes prior to behavioral testing. k) ERα antagonism via intra-BNST MPP did not alter binge EtOH drinking in low ovarian E2 status females (Ns = 8 VEH, 8 MPP). l) BNST cannula hit map (for Fig. 4d-e, 5j-l); each dot is an individual hit. …”
  15. 13995

    DataSheet_2_IKZF1plus is a frequent biomarker of adverse prognosis in Mexican pediatric patients with B-acute lymphoblastic leukemia.docx by Joaquin Garcia-Solorio (18296686)

    Published 2024
    “…</p>Results<p>We identified the IKZF1<sup>plus</sup> profile in 21.8% of patients, which was higher than that previously reported in other studies. A significantly older age (p=0.04), a trend toward high-risk stratification (p=0.06), and a decrease in 5-year Overall Survival (OS) (p=0.009) were observed, although heterogeneous treatment protocols in our cohort would have impacted OS. …”
  16. 13996

    DataSheet_1_IKZF1plus is a frequent biomarker of adverse prognosis in Mexican pediatric patients with B-acute lymphoblastic leukemia.xlsx by Joaquin Garcia-Solorio (18296686)

    Published 2024
    “…</p>Results<p>We identified the IKZF1<sup>plus</sup> profile in 21.8% of patients, which was higher than that previously reported in other studies. A significantly older age (p=0.04), a trend toward high-risk stratification (p=0.06), and a decrease in 5-year Overall Survival (OS) (p=0.009) were observed, although heterogeneous treatment protocols in our cohort would have impacted OS. …”
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    Identification of 5-FU-sensitizing genes. by Tomohiko Sakabe (282459)

    Published 2013
    “…<p>(A) Determination of a 5-FU concentration sufficient to decrease cell viability in HepG2 cells, which were treated with various concentrations of 5-FU for 72 h. …”
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