Aquaporin 2 Mutations in <i>Trypanosoma brucei gambiense</i> Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol by Fabrice E. Graf (469055)

“…Here we describe two different kinds of <i>TbAQP2</i> mutations found in <i>T. b. gambiense</i> field isolates: simple loss of <i>TbAQP2</i>, or loss of wild-type <i>TbAQP2</i> allele combined with the formation of a novel type of <i>TbAQP2/3</i> chimera. The identified mutant <i>T. b. gambiense</i> are 40- to 50-fold less sensitive to pentamidine and 3- to 5-times less sensitive to melarsoprol than the reference isolates. …”

Potential mechanisms of the decreased efficacy of Nb-015 towards Gamma and XBB variants and Nb-021 towards Omicron variant. by Jing Yang (13969)

Developmental changes in the wet weight of embryo and external yolk sac. by Yuki Honda (414507)

Albumin and CYP 3A4 staining of spheroids inside Huh7.5 cell laden hydrogels at day 20. by Bae Hoon Lee (693256)

“…The extent of CYP 3A4 expression decreased markedly from the compliant to stiff samples, especially in P12.5%, indicating that Huh7.5 cells in the compact spheroids of P12.5% might not function well.…”

Amx that only possesses the highly conserved TM2 domain is a potent inhibitor of Notch signaling. by Jose L. Salazar (3233190)

T2R neutrophils show spontaneous <i>ex vivo</i> NETs production, which decreases with thalidomide treatment. by Camila Oliveira da Silva (7365539)

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …”
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Developmental changes in gene expression involved in lipid absorption. by Yuki Honda (414507)

Developmental changes in pancreatic enzyme gene expression. by Yuki Honda (414507)

Developmental changes in gene expression of lysosomal digestive enzymes. by Yuki Honda (414507)

Improved survival and decreased viral loads of neonatal mice when pretreated with <i>Lactobacillus</i> prior to Influenza infection. by Ogan K. Kumova (7490828)

DXM treatment decreased inflammatory alterations and increased parasite load in chronically infected C57BL/6 mice. by Paulo Victor Czarnewski Barenco (560371)

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …”
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Breast Cancer 1 (BrCa1) May Be behind Decreased Lipogenesis in Adipose Tissue from Obese Subjects by Francisco J. Ortega (161440)

“…Consistent with its role limiting fatty acid biosynthesis, both <em>BrCa1</em> mRNA (3.5-fold, p<0.0001) and protein (1.2-fold, p = 0.001) were increased in pre-adipocytes, and decreased during <em>in vitro</em> adipogenesis, while P-ACC decreased during differentiation of human adipocytes (p = 0.005) allowing lipid biosynthesis. …”

State dependence of stimulus-induced variability tuning in macaque MT by Joseph A. Lombardo (5851199)

A Role for <i>Smoothened</i> during Murine Lens and Cornea Development by Janet J. Y. Choi (636307)

“…Mutant lenses were smaller and showed normal expression of p57Kip2, c-Maf, E-cadherin and Pax6, reduced expression of FoxE3 and Ptch1 and decreased nuclear Hes1. There was normal G1-S phase but decreased G2-M phase transition at E16.5 and epithelial cell death from E14.5-E16.5. …”

Developmental changes in gene expression of amino acid transporters of putative apical locality. by Yuki Honda (414507)

Developmental changes in gene expression of amino acid transporters of putative basolateral locality. by Yuki Honda (414507)

Knockdown of UAP56 impairs A/chicken/Malaysia/5858/2004 H5N1 virus growth. by Vinod R. M. T. Balasubramaniam (461446)

“…Fourty-eight hours later, depleted cells were infected with A/chicken/Malaysia/5858/2004 H5N1 at MOI of 5. …”

DataSheet_1_Increased circulating regulatory T cells and decreased follicular T helper cells are associated with colorectal carcinogenesis.docx by Qiao Meng (14368167)