24 h exposure to 5 by Kelly M. Kennedy (180156)

“…Viable MCF7 cells show significant decreases with 5 mM CHC (A, #p≤0.004 compared to control (no CHC, no lactate + glucose), ‡‡p < 0.01 compared to 40 mM lactate-treated MCF7 cells, *p = 0.003 compared to all no CHC and low CHC groups). …”

NatB inactivation decreased the level of MAPK and proposed model of EGFR/MAPK signaling regulation by NatB and the N-end rule pathways. by Zhentao Sheng (107495)

“…<p>(A-B) <i>psid-D1</i> (A) or <i>psid-D4</i> (B) clones in 3rd instar fat body, which were marked by GFP expression (pointed by arrowheads), showed decreased MAPK levels (anti-MAPK staining, red). …”

Constitutively nuclear Foxo1 reduced Na_V1.5 expression. by Weike Mao (181121)

“…<p>Western blots showed that overexpression of Foxo1-AA-GFP for 36 hours reduced Na_V1.5 protein level while it increased endogenous Foxo1 expression (A); quantitiation of Na_V1.5 protein level relative to GAPDH revealed that expression of Foxo1-AA-GFP (n = 5) significantly decreased (*p<0.05, at 10 MOI; **p<0.01 at 50 MOI) Na_V1.5 expression compared with 50 MOI GFP (n = 5) (C). …”

DataSheet_1_Mono-(2-ethylhexyl) phthalate Promotes Dengue Virus Infection by Decreasing IL-23-Mediated Antiviral Responses.pdf by Chun-Yu Lin (414543)

“…Among 89 DV-infected patients, those with DV infection-related gastrointestinal (GI) bleeding (n = 13, 15% of patients) had significantly higher DEHP exposure than those without GI bleeding (n = 76, 85% of patients), which were 114.2 ng/ml versus 52.5 ng/ml ΣDEHP in urine; p = 0.023). In an in vitro study using cultured human monocyte-derived macrophages (MDMs) to investigate the effects of MEHP, treatment increased IL-1β and TNF-α release but decreased IL-23 release, with negative correlations observed between urine ΣDEHP and serum IL-23 levels in patients. …”

DataSheet_2_Mono-(2-ethylhexyl) phthalate Promotes Dengue Virus Infection by Decreasing IL-23-Mediated Antiviral Responses.docx by Chun-Yu Lin (414543)

“…Among 89 DV-infected patients, those with DV infection-related gastrointestinal (GI) bleeding (n = 13, 15% of patients) had significantly higher DEHP exposure than those without GI bleeding (n = 76, 85% of patients), which were 114.2 ng/ml versus 52.5 ng/ml ΣDEHP in urine; p = 0.023). In an in vitro study using cultured human monocyte-derived macrophages (MDMs) to investigate the effects of MEHP, treatment increased IL-1β and TNF-α release but decreased IL-23 release, with negative correlations observed between urine ΣDEHP and serum IL-23 levels in patients. …”

Decreases in time from AHP to threshold account for increased firing of cPLA₂α^-/- SCG neurons. by Liwang Liu (424650)

“…<p>(<b>A-B)</b> Examples of differences in AP firing during a 1 sec injection of 100 pA of current. …”

Sanger sequences for CRISPR generated <i>syt7a</i> mutant alleles. by Elelbin A. Ortiz (8655285)

Table 1_SARS-CoV-2 testing strategies for a safe (post-)pandemic implementation of school music trips and their impact on participants’ health.docx by Linus Fritz Felix Möckel (21014891)

“…</sub> There was a significant decrease in cold symptoms among students (p = 0.002). …”

Image_5_Epidemiological and Clinical Characteristics of Five Rare Pathological Subtypes of Hepatocellular Carcinoma.pdf by Xiaoyuan Chen (322516)

“…This study aimed to describe the epidemiological and clinical spectrum of five rare HCC subtypes and develop a competing risk nomogram for cancer-specific survival prediction.…”

Opportunistic analysis of clinically actionable DPYD gene variants in a germline testing cohort in India by Rajdeep Raha (22056304)

“…Comparative allele frequency analysis was performed using global population datasets to identify inter-population differences.</p> <p>A total of 95 individuals (5.3%) carried at least one decreased or no function DPYD variant, indicating a significant prevalence of clinically actionable genotypes in this Indian cohort. …”

H-MSCs^WT reduced infarct size and collagen I expression 7 days post-MI. by Panpan Chen (307628)

Image_5_Characterization of Rhesus Macaque Liver-Resident CD49a+ NK Cells During Retrovirus Infections.tiff by Daniel R. Ram (5324822)

“…Specifically, our analyses found a decrease in CD49a⁺ CD107a⁺ TNFα⁺ IFNγ⁻ NK cells, with a simultaneous increase in CD49a⁺ CD107a⁺ TNFα⁻ IFNγ⁺ NK cells and the non-responsive CD49a⁺ CD107a⁻ TNFα⁻ IFNγ⁻ NK cell population following infection, suggesting both pathogenic and inflammatory changes in the NK cell functional profile. …”

image_5_Targeting and Therapy of Glioblastoma in a Mouse Model Using Exosomes Derived From Natural Killer Cells.tif by Liya Zhu (541505)

image_5_Targeting and Therapy of Glioblastoma in a Mouse Model Using Exosomes Derived From Natural Killer Cells.tif by Liya Zhu (541505)

Table1_Case Report: Chanarin-Dorfman Syndrome: A Novel Homozygous Mutation in ABHD5 Gene in a Chinese Case and Genotype-Phenotype Correlation Analysis.xlsx by Bo Liang (450389)

“…<p>The Chanarin–Dorfman syndrome (CDS) is a rare, autosomal recessively inherited genetic disease, whch is associated with a decrease in the lipolysis activity in multiple tissue cells. …”

Transcriptomic and metabolomic analyses of liver of <i>Fmo5</i>^<i>-/-</i> and WT mice. by Ian R. Phillips (5074121)

“…Red dots are genes whose expression is significantly increased or decreased in <i>Fmo5</i>^<i>-/-</i> mice with a -log₁₀ <i>q</i> above 1.301 (<i>q</i> <0.05) (grey line). …”

The Effect of Added Ligands on the Reactions of [Ni(COD)(dppf)] with Alkyl Halides: Halide Abstraction May Be Reversible by Megan E. Greaves (9353706)

“…Sterically bulky and electron-donating ligands are found to decrease the reaction rate. It was found that (i) the halide abstraction step is not always irreversible and the subsequent recombination of a nickel­(I) complex with an alkyl halide can have a significant effect on the overall rate of the reaction and (ii) some ligands lead to very stable [Ni­(dppf)­(L)₂] species. …”

Reconstructed paleo-[CO₂]_atm of Pliocene to Pleistocene compared with reconstructed paleo-temperature and benthic δ¹⁸O record. by Yuqing Wang (110531)

One-carbon metabolism perturbations in liver of <i>Fmo5</i>^<i>-/-</i> mice. by Ian R. Phillips (5074121)

“…<p>Red indicates an increase, blue a decrease and black no change in metabolite abundance or gene expression in <i>Fmo5</i>^<i>-/-</i> vs WT mouse liver. …”

Abundance of dominant phylotypes in the soil microbiome under grassland vegetation (Grassland) and artificial plantations of larch (Larch). by Ekaterina Ivanova (230383)