BCC-specific survival. by Shivani Patel (4742748)

“…Hedgehog inhibition (HHI) with vismodegib or sonidegib induces a 50–60% response rate. Long-term toxicity includes muscle spasms and weight loss leading to dose decreases. …”

Influence of Precursor Solution Composition on the Electrical Properties of Solution-Processed Indium Tin Oxide Thin Films by Jingwei Zhang (288128)

“…The results reveal that incorporating nitrate anion-based precursors and Sn (II)-based precursors in the solutions leads to the ITO film with a low resistivity of 3.5 × 10^–3 Ω cm. …”

Influence of Precursor Solution Composition on the Electrical Properties of Solution-Processed Indium Tin Oxide Thin Films by Jingwei Zhang (288128)

“…The results reveal that incorporating nitrate anion-based precursors and Sn (II)-based precursors in the solutions leads to the ITO film with a low resistivity of 3.5 × 10^–3 Ω cm. …”

Sequence analysis of continually RDV selected SARS-CoV-2_Engl2. by Agnieszka M. Szemiel (10196243)

“…Calculated from 988 mutations observed in minimum of 5 sequences. Position of mutation associated with decrease RDV sensitivity in SARS-CoV-2 is highlighted in red and sites identified in murine hepatitis virus (MHV) and Ebola virus (EBOV) are indicated in black. …”

Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms by Farman M. Abbasi (22318766)

“…Current treatments, such as teriparatide, boost bone formation but also elevate resorption, limiting their long-term effectiveness. We discovered 3-butyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-<i>d</i>]pyrimidin-4(3<i>H</i>)-one <b>(5cc)</b>, an orally active phosphodiesterase-1 (PDE1) inhibitor aimed at restoring this balance. …”

Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms by Farman M. Abbasi (22318766)

“…Current treatments, such as teriparatide, boost bone formation but also elevate resorption, limiting their long-term effectiveness. We discovered 3-butyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-<i>d</i>]pyrimidin-4(3<i>H</i>)-one <b>(5cc)</b>, an orally active phosphodiesterase-1 (PDE1) inhibitor aimed at restoring this balance. …”

Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms by Farman M. Abbasi (22318766)

“…Current treatments, such as teriparatide, boost bone formation but also elevate resorption, limiting their long-term effectiveness. We discovered 3-butyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-<i>d</i>]pyrimidin-4(3<i>H</i>)-one <b>(5cc)</b>, an orally active phosphodiesterase-1 (PDE1) inhibitor aimed at restoring this balance. …”

Image_5_LUMAN/CREB3 Plays a Dual Role in Stress Responses as a Cofactor of the Glucocorticoid Receptor and a Regulator of Secretion.TIF by Jenna Penney (5791379)

Image_5_LUMAN/CREB3 Plays a Dual Role in Stress Responses as a Cofactor of the Glucocorticoid Receptor and a Regulator of Secretion.TIF by Jenna Penney (5791379)

Image_5_LUMAN/CREB3 Plays a Dual Role in Stress Responses as a Cofactor of the Glucocorticoid Receptor and a Regulator of Secretion.TIF by Jenna Penney (5791379)

Image_5_LUMAN/CREB3 Plays a Dual Role in Stress Responses as a Cofactor of the Glucocorticoid Receptor and a Regulator of Secretion.TIF by Jenna Penney (5791379)

Image_5_LUMAN/CREB3 Plays a Dual Role in Stress Responses as a Cofactor of the Glucocorticoid Receptor and a Regulator of Secretion.TIF by Jenna Penney (5791379)

Habitual Functional Electrical Stimulation Therapy Improves Gait Kinematics and Walking Performance, but Not Patient-Reported Functional Outcomes, of People with Multiple Sclerosis... by Marietta L. van der Linden (617342)

“…Five participants exceeded the Minimally Detectable Change (MDC) for a training effect on the 10mWT, but only two did so for the 2 minWT. …”

Mutations in the QseE N-terminus impairing interaction with QseG concomitantly decrease QseE activity. by Yvonne Göpel (5549291)

Decrease in <i>D. discoideum</i> mitochondrial mRNAs during <i>L. pneumophila</i> infection. by Chenyu Zhang (107032)

Double knockout of <i>TER1</i> and <i>TER2</i> does not decrease telomere length. by Kelly Dew-Budd (2940027)

A proposed model illustrates the dynamic and profound interaction of host polyamine biosynthesis and eIF5A hypusination with KSHV infection. by Guillaume N. Fiches (9300348)

“…Lytic switch of KSHV also drive an early upregulation of eIF5A and the correlated increase of hyp-eIF5A. On the contrary, at the late stage of lytic replication expression of KSHV latent proteins diminishes, leading to decrease of ODC1 and reduction of intracellular polyamines. …”

Visible-Light Paternò–Büchi Reaction for Lipidomic Profiling at Detailed Structure Levels by Hengxue Shi (14775004)

“…Around 90% conversion can be achieved at high concentrations (>0.5 mM) for different classes of lipids but drops as the lipid concentration decreases. …”

<i>C</i>. <i>muridarum</i> respiratory infection induces CCR2 expression on lung tissue and immune cells. by Shuaini Yang (20670608)

Optical coherence tomography findings. by Eisuke Usui (12111855)

“…After PCI, hDPV significantly increased from 55.6 cm/s to 69.5 cm/s (P<0.01), with a median %hDPV increase of 27.2 (6.32–59.1) %, while %hDPV decreased in 20 (19.4%) patients. …”