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1861
AMPK phosphorylation and AC5 expression in rat AVMs in response to AMPK activation.
Published 2023Subjects: -
1862
The Type 2 Diabetes Risk Allele of <i>TMEM154</i>-rs6813195 Associates with Decreased Beta Cell Function in a Study of 6,486 Danes
Published 2015“…Significant associations between <i>TMEM154</i>-rs6813195 and the beta cell measures insulinogenic index and disposition index and between <i>FAF1</i>-rs17106184 and 2-hour serum insulin levels were selected for further investigation in additional Danish studies and results were combined in meta-analyses including up to 6,486 Danes.</p><p>Results</p><p>We confirmed associations with type 2 diabetes for five of the seven SNPs (<i>TMEM154</i>-rs6813195, <i>FAF1</i>-rs17106184, <i>POU5F1/TCF19</i>-rs3130501, <i>ARL15</i>-rs702634 and <i>ABCB9/MPHOSPH9</i>-rs4275659). …”
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1863
Inclusion of TPP side chains result in decreased melanoma cell mitochondria membrane potential, oxygen consumption, and increased DHE oxidation.
Published 2020“…<p>(A) A375 melanoma cells were treated with 0.5 μM, 1.0 μM, or 2.0 μM 5-, 10-, or 16-TPP for 1 h and analyzed for mitochondria membrane potential by the JC-1 method (* significant relative to control; p<0.05; n = 2 from 2 separate experiments; N = 4). …”
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1864
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1865
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1866
DataSheet2_Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5−/− mice, decreases plasma cholesterol and epididymal fat deposition.pdf
Published 2022“…<p>We previously showed that Fmo5<sup>−/−</sup> mice exhibit a lean phenotype and slower metabolic ageing. …”
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1867
DataSheet1_Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5−/− mice, decreases plasma cholesterol and epididymal fat deposition.PDF
Published 2022“…<p>We previously showed that Fmo5<sup>−/−</sup> mice exhibit a lean phenotype and slower metabolic ageing. …”
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1868
Contribution of GIRK2-containing channels to RMP and GABA<sub>B</sub>-induced inhibition of NPY neurons.
Published 2023“…(B, C) Bar graphs and dots summarize RMP (−47.9 ± 0.9 mV, <i>n</i> = 64, for NPY<sup>G2WT</sup> and −44.5 ± 0.7 mV, <i>n</i> = 41, for NPY<sup>G2KO</sup>, df = 103, t = 2.556, <i>p</i> = 0.012) (B) and input resistance (2.35 ± 0.11 GΩ, <i>n</i> = 64, for NPY<sup>G2WT</sup> and 2.78 ± 0.11 GΩ, <i>n</i> = 41, for NPY<sup>G2KO</sup>, df = 103, t = 2.590, <i>p</i> = 0.011) (C) of NPY<sup>G2WT</sup> (<i>n</i> = 64, black) and NPY<sup>G2KO</sup> (<i>n</i> = 41, red) neurons. …”
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1869
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1872
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1875
Decrease in cell migration and adhesion of MCF10A cells after knockdown of <i>MYO1C</i>.
Published 2016“…A dose-dependent decrease in relative cell index response to MYO1C depletion was observed reaching to a significant value with concentrations of 5 and 10 nM of <i>MYO1C</i>-siRNA at 48 hours post-transfection compared to control cells (mock transfection). …”
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1876
There is a significant decrease in fibroblast, α-SMA, and Ly6C staining accompanied with a decrease in proliferation, and increase in cell death in the outflow vein removed <i>Iex-...
Published 2014“…</b> Pooled data from the semiquantitative analysis for intensity of Fsp-1 staining in the vessel wall of the outflow vein specimens removed from <i>Iex-1</i> KO and WT mice. There is a significant decrease in the mean Fsp-1 staining in the <i>Iex-1</i> KO animals when compared to WT controls (P<0.05). …”
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1877
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1878
A decrease in the invasiveness of <i>Candida albicans</i> into Caco-2 cells parallels the differentiation of intestinal epithelial cells.
Published 2016“…The gene expression levels of Apolipoprotein A-IV (ΔΔCt) were statistically lower after 1, 2, 3 and 5 days post-seeding than at day 15 as a result of incomplete differentiation (*<i>p <</i> 0.05, Mann–Whitney test). …”
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1879
The Transition from a Compensatory Increase to a Decrease in C-peptide During the Progression to Type 1 Diabetes and Its Relation to Risk
Published 2022“…Conclusions</p> <p>A transition from an increase to a decrease in AUC C-peptide approximately 1.5 years pre-diagnosis was validated in two independent cohorts. …”
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1880