Data_Sheet_3_Benefits of Home-Based Exercise Training Following Critical SARS-CoV-2 Infection: A Case Report.PDF by Igor Longobardi (11929604)

“…A 67-year-old woman who had critical COVID-19 disease [71 days of hospitalization, of which 49 days were in the intensive care unit (ICU) with invasive mechanical ventilation due to respiratory failure] underwent a 10-week HBET aiming to recovering overall physical condition. …”

Table_1_Mechanoresponsive Smad5 Enhances MiR-487a Processing to Promote Vascular Endothelial Proliferation in Response to Disturbed Flow.DOCX by Wei-Li Wang (10671738)

“…MiR-487a expression was promoted by nuclear phospho-Smad5, which bound to primary-miR-487a to facilitate miR-487a processing. …”

Table_2_Mechanoresponsive Smad5 Enhances MiR-487a Processing to Promote Vascular Endothelial Proliferation in Response to Disturbed Flow.DOCX by Wei-Li Wang (10671738)

“…MiR-487a expression was promoted by nuclear phospho-Smad5, which bound to primary-miR-487a to facilitate miR-487a processing. …”

The relationship between diabetes and colorectal cancer prognosis: A meta-analysis based on the cohort studies by Bo Zhu (118038)

“…</p><p>Results</p><p>The results found that compared to patients without diabetes, patients with diabetes will have a 5-year shorter survival in colorectal, colon and rectal cancer, with a 18%, 19% and 16% decreased in overall survival respectively. …”

Image_5_Predictive value of a stemness-based classifier for prognosis and immunotherapy response of hepatocellular carcinoma based on bioinformatics and machine-learning strategies... by Erbao Chen (13909256)

Animal-related factors associated with moderate-to-severe diarrhea in children younger than five years in western Kenya: A matched case-control study by Anne Conan (628578)

“…Variables that were associated with decreased risk of MSD were washing hands after animal contact (matched odds ratio [MOR] = 0.2; 95% CI 0.08–0.7), and presence of adult sheep that were not confined in a pen overnight (MOR = 0.1; 0.02–0.5). …”

Poly I:C fails to restore hepatic TRAIL⁺ NK cells after hepatectomy in CXCR3 KO mice. by Takuya Yano (415157)

Fig 3 - by Bodhayan Prasad (13002044)

“…<b>(B)</b> Area Under the Curve (AUC) of training and test set vs. number of protein features. A set of 17 proteins along with gender and BLDAS gave the maximum mean AUC of 0.86 on test set without decreasing the training set’s AUC. …”

320-row CT transcatheter aortic valve replacement planning with a single reduced contrast media bolus injection by Daddy Mata-Mbemba (5746847)

“…<div><p>Objective</p><p>To reduce the iodine load required for CT Transcatheter Aortic Valve Replacement (TAVR) planning on a 320-row scanner by acquiring the two CT TAVR steps (ECG-gated aortic root CTA and non-gated aorto-ilio-femoral CTA) within a single contrast media bolus injection.…”

Data_Sheet_1_Renal X-inactivation in female individuals with X-linked Alport syndrome primarily determined by age.PDF by Roman Günthner (8435811)

“…A total of 56 females with a heterozygous disease-causing COL4A5 variant and a mean age of 31.6 ± 18.3 SD years were included in this study. …”

Further optimisation and <i>in vitro</i> characterization of influenza A reporter viruses. by Monique I. Spronken (779529)

(A) Activity of SOD under B stress; (B) Activity of POD under B stress; (C) Activity of CAT under B stress; (D) Activity of APX under B stress; (E) Content of MDA under B stress ac... by Qiang Li (8118)

Exhumation and deformation history of the lower crustal section of the Valstrona di Omegna in the Ivrea Zone, southern Alps by S. Siegesmund (2845832)

Image_4_Substrate Specificity of Acyltransferase Domains for Efficient Transfer of Acyl Groups.TIF by Jie-Jie Shen (5600129)

“…In Streptomycestsukubaensis YN06, we found that AT4_FkbB [an AT in the fourth module of tacrolimus (FK506) PKS] transferred both allylmalonyl (allmal) and emthylmalonyl (ethmal) units to ACPs, which was supposed responsible for the production of both FK506 and its analog FK520, respectively. Mutations of five residues in AT4_FkbB (Q119A, L185I-V186D-V187T, and F203L) caused decreased efficiency of allmal transfer, but a higher ratio of ethmal transfer, supposedly due to less nucleophilic attacks between Ser599 in the active site of AT4_FkbB and the carbonyl carbon in the allmal unit, as observed from molecular dynamics simulations. …”

Image_3_Substrate Specificity of Acyltransferase Domains for Efficient Transfer of Acyl Groups.TIF by Jie-Jie Shen (5600129)

“…In Streptomycestsukubaensis YN06, we found that AT4_FkbB [an AT in the fourth module of tacrolimus (FK506) PKS] transferred both allylmalonyl (allmal) and emthylmalonyl (ethmal) units to ACPs, which was supposed responsible for the production of both FK506 and its analog FK520, respectively. Mutations of five residues in AT4_FkbB (Q119A, L185I-V186D-V187T, and F203L) caused decreased efficiency of allmal transfer, but a higher ratio of ethmal transfer, supposedly due to less nucleophilic attacks between Ser599 in the active site of AT4_FkbB and the carbonyl carbon in the allmal unit, as observed from molecular dynamics simulations. …”

Image_2_Substrate Specificity of Acyltransferase Domains for Efficient Transfer of Acyl Groups.TIF by Jie-Jie Shen (5600129)

“…In Streptomycestsukubaensis YN06, we found that AT4_FkbB [an AT in the fourth module of tacrolimus (FK506) PKS] transferred both allylmalonyl (allmal) and emthylmalonyl (ethmal) units to ACPs, which was supposed responsible for the production of both FK506 and its analog FK520, respectively. Mutations of five residues in AT4_FkbB (Q119A, L185I-V186D-V187T, and F203L) caused decreased efficiency of allmal transfer, but a higher ratio of ethmal transfer, supposedly due to less nucleophilic attacks between Ser599 in the active site of AT4_FkbB and the carbonyl carbon in the allmal unit, as observed from molecular dynamics simulations. …”

Image_1_Substrate Specificity of Acyltransferase Domains for Efficient Transfer of Acyl Groups.TIF by Jie-Jie Shen (5600129)

“…In Streptomycestsukubaensis YN06, we found that AT4_FkbB [an AT in the fourth module of tacrolimus (FK506) PKS] transferred both allylmalonyl (allmal) and emthylmalonyl (ethmal) units to ACPs, which was supposed responsible for the production of both FK506 and its analog FK520, respectively. Mutations of five residues in AT4_FkbB (Q119A, L185I-V186D-V187T, and F203L) caused decreased efficiency of allmal transfer, but a higher ratio of ethmal transfer, supposedly due to less nucleophilic attacks between Ser599 in the active site of AT4_FkbB and the carbonyl carbon in the allmal unit, as observed from molecular dynamics simulations. …”

Table_1_Substrate Specificity of Acyltransferase Domains for Efficient Transfer of Acyl Groups.DOC by Jie-Jie Shen (5600129)

“…In Streptomycestsukubaensis YN06, we found that AT4_FkbB [an AT in the fourth module of tacrolimus (FK506) PKS] transferred both allylmalonyl (allmal) and emthylmalonyl (ethmal) units to ACPs, which was supposed responsible for the production of both FK506 and its analog FK520, respectively. Mutations of five residues in AT4_FkbB (Q119A, L185I-V186D-V187T, and F203L) caused decreased efficiency of allmal transfer, but a higher ratio of ethmal transfer, supposedly due to less nucleophilic attacks between Ser599 in the active site of AT4_FkbB and the carbonyl carbon in the allmal unit, as observed from molecular dynamics simulations. …”

Data_Sheet_1_Host Factor Nucleoporin 93 Is Involved in the Nuclear Export of Influenza Virus RNA.DOCX by Yuri Furusawa (5546819)

Description of biomarkers, gene, primer sequences and NCBI accession numbers. by Conceição S. Martins (468492)