Video 5_Clinical feasibility study of transcatheter edge-to-edge mitral valve repair in dogs with the canine V-Clamp device.mp4 by Brianna M. Potter (20401199)

“…</p>Animals<p>Fifty client-owned dogs with severe degenerative MR operated over a 28-month period.</p>Methods<p>TEER was performed using the canine mitral V-Clamp via a transapical approach using transesophageal echocardiographic and fluoroscopic guidance. …”

Following the initiation of VF, wavebreak is shown in a time-lapse series of images (left to right, top to bottom) in 10ms intervals. by Aditya V. S. Ponnaluri (3164673)

DataSheet_1_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.zip by Xiao-yang Gong (13103400)

“…</p>Results<p>To the best to our knowledge, we present for the first time an overview of the genomic mutation spectrum of early-stage laryngeal cancers. A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Table5_Temporal dynamics of the chicken mycobiome.xlsx by Cary Pirone Davies (14261792)

Image5_Temporal dynamics of the chicken mycobiome.pdf by Cary Pirone Davies (14261792)

FISH and array CGH analyses in the proband (III-5). by Tsutomu Ogata (106859)

“…Black, red, and green dots denote signals indicative of the normal, the increased (>+0.5), and the decreased (<−0.8) copy numbers, respectively. …”

Model of the ETS-5/INS-1 regulatory module. by Ava Handley (12575434)

“…Worms that experience excess dietary glucose down-regulate ETS-5 and INS-1 levels in the BAG neurons. This suppression of ETS-5/INS-1 leads to decreased intestinal DAF-2 activity, and increased intestinal DAF-16 levels. …”

Image 5_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.tif by M. Elakkya (21760439)

“…Under salt and osmotic stress, A. chroococcum W5 metabolomic profiling revealed adaptive responses, including elevated levels of osmoprotectants (proline, glycerol) and oxidative stress markers such as 2-hydroxyglutarate, while putrescine and glycine decreased.…”

Table 5_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.docx by M. Elakkya (21760439)

“…Under salt and osmotic stress, A. chroococcum W5 metabolomic profiling revealed adaptive responses, including elevated levels of osmoprotectants (proline, glycerol) and oxidative stress markers such as 2-hydroxyglutarate, while putrescine and glycine decreased.…”

Enzymatic probing of 5′-labeled mt tRNA by Masashi Arita (22192)

“…The closed and open triangles indicate the decreasing amounts of RNase T and V, respectively. Symbols: dash, untreated tRNA; N, alkaline ladder; T, RNase T ladder; and Nc, ladder of digestion with endonuclease as a size marker for RNase V, which digests at the 5′ side of phosphodiester bonds. () Secondary structure of mt tRNA. …”

Structure of the V66I:V73I:Y160F PfPNP mutant with transition state inhibitor ImmH. by Teraya M. Donaldson (506944)

“…The highlighted imino nitrogen is in <i>blue</i> and the 5′-hydroxyl oxygen is in <i>red</i>. <b>B</b>) Side by side images of the decreased convalent interactions located in the enzymatic pocket of V66I:V73I:Y160F PfPNP mutant (3FOW) on the right with WT PfPNP (1NW4) as a comparison.…”

Dynamics of CMV-specific CD8⁺ T-cells and CD8⁺ T_EM/EMRA cells in CMV+ and CMV- individuals. by Sara P. H. van den Berg (8703927)

Western blot analysis of myocardial IRF5 immunoprecipitates. by Hao Xu (6530)

Changes in the number of HAdV copies over time. by Nozomu Hanaoka (456195)

“…<p>A. Changes in the HAdV genome copy number at the initial, second, and third visits. …”

Table_5_UCA1 executes an oncogenic role in pancreatic cancer by regulating miR-582-5p/BRCC3.xlsx by Xiaole Hu (3335241)

“…</p>Conclusion<p>UCA1 acted as an oncogene in pancreatic cancer by partly regulating miR-582-5p/BRCC3, which could be a new therapeutic target for pancreatic cancer.…”

Proliferation and ‘memory generation potential’ of CD62Lhi memory cells increases with time after infection. by Matthew D. Martin (803107)

Image5_Magnetospheric responses to solar wind Pc5 density fluctuations: Results from 2D hybrid Vlasov simulation.PNG by Hongyang Zhou (2352637)

“…With the new time-varying boundary setup, we introduce a monochromatic Pc5 range periodic density variation in the solar wind. …”

Effect of vinculin and Rab5 expression on cellular uptake. by Makoto Hagiwara (513898)

“…Uptake of pHrodo red-labeled <i>S. aureus</i>, transferrin Alexa 555, albumin Alexa 555, Lucifer yellow, and FM 4-64 increased in HA-Rab5 (WT)- and HA-Rab5 (Q79L)-expressing cells, whereas uptake of each of the indicators was decreased in HA-Rab5 (S34N)-expressing cells. …”

Uncovering the F‑Actin-Based Nuclear Egress Mechanism of Newly Synthesized Influenza A Virus Ribonucleoprotein Complexes by Single-Particle Tracking by Cong Yu (53009)

“…The disruption of nuclear F-actin after treatment with microfilament inhibitors caused a considerable decrease in vRNPs motility and suppressed the nuclear export of newly produced vRNPs, indicating that the slow, directed movement plays a crucial role in facilitating the nuclear egress of vRNPs. …”

Uncovering the F‑Actin-Based Nuclear Egress Mechanism of Newly Synthesized Influenza A Virus Ribonucleoprotein Complexes by Single-Particle Tracking by Cong Yu (53009)

“…The disruption of nuclear F-actin after treatment with microfilament inhibitors caused a considerable decrease in vRNPs motility and suppressed the nuclear export of newly produced vRNPs, indicating that the slow, directed movement plays a crucial role in facilitating the nuclear egress of vRNPs. …”