Stearoyl Co-A Δ9 Desaturase Activity Is Required for Germline-Mediated Longevity. by Jérôme Goudeau (228021)

“…<p>(A) Eliminating the SCD activity by deleting both <i>fat-6</i> and <i>fat-7</i> in <i>glp-1(e2141ts)</i> mutants decreases its lifespan significantly (<i>p</i><0.001, 46% reduction in mean lifespan). …”

Ectopic <i>Lxn</i> expression increases apoptosis of A20 cells. by Yi Liu (36759)

“…BrdU and 7AAD staining and flow cytometric analysis was used for detecting different phases of the cell cycle (G0/G1, S, G2/M) and apoptotic (A) and necrotic (N) population. A representative flow cytometric file from Day 5 of culture is shown. …”

Raman spectra of myelin sheath of sciatic nerve fiber. by Natalia N. Rodionova (4452793)

The dynamics of OPD profile changes along the scan-line (μM) through NR. by Natalia N. Rodionova (4452793)

Study of myelin structure changes during the nerve fibers demyelination - Fig 1 by Natalia N. Rodionova (4452793)

Comparison of histologic markers of middle ear inflammation when transtympanic prednisolone (Pred) or aldosterone (Aldo) were given three (+ 3h) or six (+ 6h) hours after inoculati... by Jessyka G. Lighthall (712759)

Data Sheet 1_Polarization of Vδ2 T cells to a Th2-like phenotype promotes plasmablast differentiation and possesses pro-fibrotic properties in IgG4-related disease.docx by Jieqiong Li (327149)

“…</p>Results<p>Patients with IgG4-RD exhibited decreased peripheral Vδ2 T cells displaying a Th2-like phenotype characterized by elevated Th2 cytokine production and activated IL-21—STAT3—Blimp-1—GATA3 pathway. …”

Tamoxifen decreases fasting glucose and improves glucose tolerance in C57Bl/6J mice; Tamoxifen significantly reduces β-cell proliferation in C57Bl/6J mice. by Surl-Hee Ahn (7354373)

Data_Sheet_1_RK-33, a small molecule inhibitor of host RNA helicase DDX3, suppresses multiple variants of SARS-CoV-2.PDF by Farhad Vesuna (354371)

“…However, evolving variants of the virus appear to be more transmissive and vaccine efficacy toward them is waning. As a result, SARS-CoV-2 will continue to have a deadly impact on public health into the foreseeable future. …”

Down-Regulation of Canonical and Up-Regulation of Non-Canonical Wnt Signalling in the Carcinogenic Process of Squamous Cell Lung Carcinoma by Domokos Bartis (364771)

“…The molecular changes were tested in primary small airway epithelial cells (SAEC) and various lung cancer cell lines (e.g. A549, H157, etc). Our studies identified Wnt11 and Wnt5a as regulators of cadherin expression and potentiated relocation of β-catenin to the nucleus as an important step in decreased cellular adhesion. …”

Data Sheet 1_Understanding the long-term interplay of SARS-CoV-2 immune and inflammatory responses with proteases in COVID-19 recovery: a longitudinal study.pdf by Natalia Ćwilichowska-Puślecka (21515129)

“…</p>Results<p>Our comprehensive approach revealed significant changes in the immune system over time, highlighting the role of specific immune cells and proteases in the recovery process. Key findings include a decreasing deregulatory effect on immune responses exerted by subsequent SARS-CoV-2 variants Alpha, Delta, and Omicron.…”

Study of myelin structure changes during the nerve fibers demyelination - Fig 6 by Natalia N. Rodionova (4452793)

Table_5_Analysis of LINE1 Retrotransposons in Huntington’s Disease.XLSX by Lavinia Floreani (11946644)

Decreased Th2 and increased Th1 cytokines in LPMCs and MLNs from <i>Trichuris muris–</i>infected mice residing outdoors compared to laboratory conditions at 3 weeks p.i. by Jacqueline M. Leung (120235)

Mitotic catastrophe is dependent on CRM-1 dysregulation. by Zachary J. Hough (20840430)

Fig 2 - by Carla Schenker (6661655)

Akt3 depletion results in micronuclei formation. by Zachary J. Hough (20840430)

ROS reduces the expression of Akt3, WDR12 and Aurora B leading to micronuclei. by Zachary J. Hough (20840430)

Image_1_Case Report: Difficulties in the Treatment of a 12-Year-Old Patient With Homozygous Familial Hypercholesterolemia, Compound Heterozygous Form − 5 Years Follow-Up.JPEG by Lyudmila Vladimirova-Kitova (11537353)

“…Initial treatment, based on European recommendations, included Atorvastatin 20 mg and Ezetimibe 10 mg and led to a decrease in LDL-C by 46% for 5 months; however, the patient developed severe statin intolerance. …”

Supplemental data 3. by Zachary J. Hough (20840430)

“…Akt3 null hearts at midgestation (E14.5), a stage in which proliferation is occurring, have decreased Aurora B expression, increased CRM-1 expression, decreased proliferation, and increased apoptosis. …”