Efficacy and safety of lorcaserin in obesity: a systematic review and meta-analysis of randomized controlled trials by Awadhesh Kumar Singh (6174640)

“…<p><b>Background</b>: Lorcaserin is a novel, selective 5-hydroxytryptamine 2C serotonin receptor agonist, approved for the treatment of obesity. …”

Glyphosate alters the composition, but not density, of the <i>A</i>. <i>gambiae</i> midgut microbiota. by Daniel F. Q. Smith (10788903)

“…Each treatment group represents 5 individual mosquito midguts. For underlying data, please see Data Availability section and/or <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001182#pbio.3001182.s010" target="_blank">S1 Table</a>. …”

Effect of a rosmarinic acid supplemented hemodialysis fluid on inflammation of human vascular endothelial cells by W-J. Wang (6513719)

“…Inhibition of proinflammatory mediator production in HUVECs by RA supplementation to HDF was significant in a dose-dependent manner. Exposure to RA-supplemented HDF resulted in a decrease in nitric oxide synthase expression and reduction of NO production in LPS-stimulated HUVECs. …”

Relative effort (+ standard deviation), estimated, when optimising for A) profit and B) ecological stability. by Johanna Jacomina Heymans (219773)

“…This is because the profit that can be made given the prices of the species caught by these fleets is much lower for the demersal fleets than for the Nephrops fleets. Nephrops command a high ex-vessel price (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0020239#pone.0020239.s005" target="_blank">Table S5</a>), so it is unsurprising that the optimisation seeks to maximise effort and yield from this fleet. …”

Numerical investigation on the impact of natural convection on a multi-inlet industrial rooftop photovoltaic system by Xiaomeng Wang (348745)

“…Especially on the roofs of large industrial plants, it is necessary to install as many photovoltaic panels as possible while avoiding a significant increase in panel temperature that could lead to a decrease in efficiency. …”

Structural and functional analysis of cell-free produced PfAQP without a GFP fusion. by Annika Müller-Lucks (147176)

“…Changes in the light scattering intensity reflect liposome shrinkage due to water efflux (increase in light scattering) and liposome swelling due to glycerol plus secondary water influx (decrease in light scattering). Note the difference of the scale of the abscissae as a consequence of lower glycerol permeability by at least one order of magnitude. …”

Changes over time in the genetic parameters of milk production and functional traits in a Holstein population by Juana Lucia Chuma-Alvarez (22265886)

“…In functional traits, genetic variances and heritabilities remained unchanged, while a decrease over time was observed in environmental variances for SCS, CI and AFC. …”

Disease course of Chronic Relapsing Inflammatory Optic Neuropathy (CRION) in a single care center by Luis Enrique MOLINA-CARRIÓN (12687286)

“…Currently, all patients are on maintenance treatment with mycophenolate mofetil or rituximab with a decrease in relapsing rate. Conclusions: Diagnosis of CRION is challenging and should be kept in mind. …”

Predicting the Impact of Vaccination on the Transmission Dynamics of Typhoid in South Asia: A Mathematical Modeling Study by Virginia E. Pitzer (143006)

“…Vaccination was predicted to confer substantial indirect protection leading to a decrease in the incidence of typhoid in the short term, but (intuitively) typhoid incidence was predicted to rebound 5–15 years following a one-time campaign.…”

Cyclin-dependent kinase inhibitor flavopiridol promotes remyelination in a cuprizone induced demyelination model by Guiyun Mi (835541)

“…In the first experiment of this study, we examined the expression of cell cycle related genes in brains of mice following CPZ administration for 5 weeks by means of microarray assay. In addition, we performed a double labeling of BrdU and Ki-67 to calculate cell cycle exit index in the mice. …”

DataSheet2_A Zebrafish Model of Neurotoxicity by Binge-Like Methamphetamine Exposure.xlsx by Juliette Bedrossiantz (11736794)

“…After an initial testing at 20 and 40 mg/L for 48 h, the later METH concentration was selected for developing the model and the effects on the brain monoaminergic profile, locomotor, anxiety-like and social behaviors as well as on the expression of key genes of the catecholaminergic system were determined. A concentration- and time-dependent decrease in the brain levels of dopamine (DA), norepinephrine (NE) and serotonin (5-HT) was found in METH-exposed fish. …”

SapA is required for NTHI to directly counter host defensin lethality <i>in vivo.</i> by Catherine L. Shelton (340365)

“…Black and gray horizontal lines (panels A and B) represent the geometric mean value of each cohort (n = 5 animals per cohort). …”

Optimization of a glucagon-like peptide 1 receptor antagonist antibody for treatment of hyperinsulinism by Sean M. Peterson (820405)

DataSheet1_Differential effects of two-hit models of acute and ventilator-induced lung injury on lung structure, function, and inflammation.PDF by Jill Bilodeaux (16652376)

“…The effects of injury were quantified using invasive lung function measurements recorded during PEEP ladders where the end-expiratory pressure was increased from 0 to 15 cm H₂O and decreased back to 0 cmH₂O in steps of 3 cmH₂O. …”

Computation of marginal distributions for all variables (arcs and nodes) of a hypothetical toy graph. by Andrey Rzhetsky (42928)

“…</p> <p>If both probabilities (<i>P</i>(<i>A_V,U</i> = −1) and <i>P</i>(<i>A_V,U</i> = 1)) drop to zero (indicating that <i>P</i>(<i>A_V,U</i> = 0) = 1), then the edge vanishes from the figure, indicating the <i>no effect</i> value.…”

Alternating evolutionary pressure in a genetic algorithm facilitates protein model selection-1 by Marc N Offman (3649)

The effects of a partitioned gene repertoire of on antigenic diversity and the acquisition of clinical immunity-1 by Mario Recker (88496)

Optimization of a cationic liposomal gene delivery system and study of its endocytic pathway by Ting Yu (156230)

“…The results showed that the liposome/DNA (LP/DNA) system had spherical morphology, with a particle size of around 150 nm and zeta potential of approximately 30 mV. …”

FINANCIAL PERFORMANCE EVALUATION OF FOREST VILLAGE COOPERATIVES: A MULTI-CRITERIA TOPSIS APPROACH by Mehmet Korkmaz (6097205)

“…The most important reasons for low financial performance include the fact that: (i) the cooperatives mainly operated in the field of wood production and the business volume in that field was inadequate, (ii) their capital was insufficient since the members assumed a lower share, (iii) they had challenges accessing constant funds for investment, (iv) the state subsidies decreased, (v) the number of members was low, and (vi) they were unable to compete with large companies.…”

Cold Atmospheric Plasma: A Promising Complementary Therapy for Squamous Head and Neck Cancer by Christian Welz (414034)

“…Effects on the cell viability, DNA fragmentation and apoptosis induction were evaluated with the MTT assay, alkaline microgel electrophoresis (comet assay) and Annexin-V/PI staining. MTT assay revealed that the CAP treatment markedly decreases the cell viability for all tested treatment times (30, 60, 90, 120 and 180 s). …”