β-galactosidase reporter viruses reveal an increased frequency of gene expression in the absence of the LAT RNAs. by Michael P. Nicoll (3175491)

Enzyme Active Site Loop Revealed as a Gatekeeper for Cofactor Flip by Targeted Molecular Dynamics Simulations and FRET-Based Kinetics by Sophie Rahuel-Clermont (6235601)

“…To monitor cofactor movements within the active site, we used an intrinsic fluorescence resonance energy transfer signal between Trp177 and the reduced nicotinamide moiety to kinetically track the flip during the catalytic cycle of retinal dehydrogenase 2 (ALDH1A2). Decreasing loop flexibility by substituting Ala for Gly271 drastically reduced the rate constant associated with this movement that became rate-limiting. …”

Detection of epistasis is rescued by simultaneous analysis of multiple independently-evolved populations. by Gabriele Pedruzzi (5753792)

Image_5_Bacteroides fragilis Prevents Clostridium difficile Infection in a Mouse Model by Restoring Gut Barrier and Microbiome Regulation.JPEG by Huimin Deng (1844299)

“…Notably, the abundance of Bacteroides fragilis was reported to be significantly decreased in CDAD patients. This study aimed to clarify the prophylactic effects of B. fragilis strain ZY-312 in a mouse model of C. difficile infection (CDI). …”

Table_5_Balance Adaptation While Standing on a Compliant Base Depends on the Current Sensory Condition in Healthy Young Adults.DOCX by Stefania Sozzi (9193071)

DataSheet1_Potential causal associations of PM2.5 and osteoporosis: a two-sample mendelian randomization study.docx by Yi Zhang (9093)

“…</p><p>Results: The results indicated that PM2.5 was not correlated with a decrease in FN-BMD (β: −0.305, 95%CI: −0.762, 0.153), LS-BMD (β: 0.134, 95%CI: −0.396, 0.666), FA-BMD (β: -0.056, 95%CI: −1.172,1.060), and HE-BMD (β: −0.084, 95%CI: −0.261,0.093). …”

Image_1_A highly susceptible hACE2-transgenic mouse model for SARS-CoV-2 research.PDF by Gang Liu (81776)

“…Overexpression of hACE2 did not pose a significant effect on weight growth. After SARS-CoV-2 inoculation, mice showed obvious viral replication and production of inflammation within 7 days, with a gradual decrease in body weight until death. …”

Image_5_Bacteroides fragilis Prevents Clostridium difficile Infection in a Mouse Model by Restoring Gut Barrier and Microbiome Regulation.JPEG by Huimin Deng (1844299)

“…Notably, the abundance of Bacteroides fragilis was reported to be significantly decreased in CDAD patients. This study aimed to clarify the prophylactic effects of B. fragilis strain ZY-312 in a mouse model of C. difficile infection (CDI). …”

Image 5_Risk factors for thoracic aortic aneurysm and dissection among diabetic patients: a nationwide population-based study.tif by Suk Kyung Lim (22382302)

Table_5_Nutrient Scarcity in a New Defined Medium Reveals Metabolic Resistance to Antibiotics in the Fish Pathogen Piscirickettsia salmonis.pdf by Javiera Ortiz-Severín (8273808)

Table_1_Resveratrol enhances A1 and hinders A2A adenosine receptors signaling in both HeLa and SH-SY5Y cells: Potential mechanism of its antitumoral action.docx by Sonia Muñoz-López (11369454)

“…Interestingly, these effects were almost identical in HeLa and SH-SY5Y cells suggesting that resveratrol enhances A₁ and hinders A_2A adenosine receptors signaling as part of a potential mechanism of antitumoral action.…”

A priori model predictions. by Adam M. Roth (19845864)

Table_5_Effect of BAFF blockade on the B cell receptor repertoire and transcriptome in a mouse model of systemic lupus erythematosus.xlsx by Tao Huang (110613)

A Multi-scale Computational Platform to Mechanistically Assess the Effect of Genetic Variation on Drug Responses in Human Erythrocyte Metabolism - Fig 5 by Nathan Mih (3146436)

Image_5_PvdQ Quorum Quenching Acylase Attenuates Pseudomonas aeruginosa Virulence in a Mouse Model of Pulmonary Infection.pdf by Putri D. Utari (5143832)

“…We then treated mice with PvdQ during lethal P. aeruginosa pulmonary infection and that resulted in a 5-fold reduction of lung bacterial load and a prolonged survival of the infected animals with the median survival time of 57 hin comparison to 42 h for the PBS-treated group. …”

Pelvis and femur shape prediction using principal component analysis for body model on seat comfort assessment. Impact on the prediction of the used palpable anatomical landmarks a... by Léo Savonnet (7314200)

“…Results also show that the PCA based method is a good alternative to predict hip and lumbosacral joint centers with an average error of 5.0 and 9.2 mm respectively.…”

HI promotes FOXO3a dephosphorylation, which induces FOXO3a translocation into the nucleus and upregulates the expression of Bim and CC3. by Deyuan Li (769599)

“…However, p-FOXO3a levels decreased from 0.5 to 48 h and returned to baseline at 72 h after HI (A). …”

Birds invest wingbeats to keep a steady head and reap the ultimate benefits of flying together by Lucy A. Taylor (492318)

“…Here, we compared the flight characteristics of homing pigeons (<i>Columba livia</i>) flying solo and in pairs released from a site 7 km from home, using high-precision 5 Hz global positioning system (GPS) and 200 Hz tri-axial accelerometer bio-loggers. …”

Study site. by Ása Johannesen (12152684)

Table_5_Trends in incidence and mortality of esophageal cancer in China 1990−2019: A joinpoint and age-period-cohort analysis.xlsx by Fajun Li (13247448)

“…The time period showed a trend of first rising and then decreasing, and the RR of time period effect was lower in 2015 than that in 1990 in females regarding both incidence and mortality, whereas males showed a significant upward trend in both incidence and mortality. …”