Table_1_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.docx by Xiao-yang Gong (13103400)

“…</p>Results<p>To the best to our knowledge, we present for the first time an overview of the genomic mutation spectrum of early-stage laryngeal cancers. A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Image_1_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.tif by Xiao-yang Gong (13103400)

“…</p>Results<p>To the best to our knowledge, we present for the first time an overview of the genomic mutation spectrum of early-stage laryngeal cancers. A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Table_3_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.docx by Xiao-yang Gong (13103400)

“…</p>Results<p>To the best to our knowledge, we present for the first time an overview of the genomic mutation spectrum of early-stage laryngeal cancers. A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Decreased self-renewal capacity associated with senescence was prevented in human MSCs following treatment with Ki16425, an LPA₁/LPA₃ antagonist. by Masahiko Kanehira (183764)

“…Fold-change represents decrease in band intensity of Ki16425 treatment for 18 days compared with a control treatment for the same period of time. …”

Table 1_A national population-based study of mortality and risk factors in COVID-19-hospitalized patients in Spain (2020–2021).docx by José-Manuel Ramos-Rincón (10428656)

“…Hospitalization rates dropped from 697/100,000 people to 411/100,000, and in-hospital mortality (IHM) decreased from 16.2 to 11.5% (adjusted odds ratio [AOR]: 0.71, 95% CI: 0.70–0.73, p < 0.001). …”

Synthesis and Properties of the Heterospin (<i>S</i>₁ = <i>S</i>₂ = ¹/₂) Radical-Ion Salt Bis(mesitylene)molybdenum(I) [1,2,5]Thiadiazol... by Nikolay A. Pushkarevsky (1565458)

“…Low-temperature interaction of [1,2,5]­thiadiazolo­[3,4-<i>c</i>]­[1,2,5]­thiadiazole (<b>1</b>) with MoMes₂ (Mes = mesitylene/1,3,5-trimethylbenzene) in tetrahydrofuran gave the heterospin (<i>S</i>₁ = <i>S</i>₂ = ¹/₂) radical-ion salt [MoMes₂]⁺[<b>1</b>]⁻ (<b>2</b>) whose structure was confirmed by single-crystal X-ray diffraction (XRD). …”

Decreased Caffeine-Induced Locomotor Activity via Microinjection of CART Peptide into the Nucleus Accumbens Is Linked to Inhibition of the pCaMKIIa-D₃R Interaction by Qiang Fu (129583)

“…After repeated oral administration of caffeine (30 mg/kg) for five days, microinjection of CART peptide (0.08 μM/0.5 μl/hemisphere) into the NAc affected locomotor behavior. …”

Expression of the KSHV miRNA cluster reduces mitochondrial biogenesis. by Ohad Yogev (252095)

Table_5_Resistant Potato Starch Alters the Cecal Microbiome and Gene Expression in Mice Fed a Western Diet Based on NHANES Data.xlsx by Allen D. Smith (8798879)

“…To address this, mice were fed a Total Western Diet (TWD) based on National Health and Nutrition Examination Survey (NHANES) data that mimics the macro and micronutrient composition of a typical American diet for 6 weeks and then supplemented with 0, 2, 5, or 10% of the RS2, resistant potato starch (RPS), for an additional 3 weeks. …”

Disorder predictions for the Bex protein family in human: A) Bex1 and Bex2; B) Bex3 and Bex5; C) Bex4. by Eva M. Fernandez (610643)

DataSheet1_Levels of hormones regulating appetite and energy homeostasis in response to a 1.5-Year combined lifestyle intervention for obesity.docx by Susanne Kuckuck (14648639)

“…</p><p>Results: Initial weight loss at T1 was maintained at T2 (−5.0%, p < 0.001), and accompanied by decreased leptin and insulin levels at T1 and T2 (all p < 0.05) compared to T0. …”

The 50 pentatonic scales whose intervals conform most closely to a harmonic series out of ∼4×10⁵ possibilities examined. by Kamraan Z. Gill (368776)

Time-dependent morphological changes (A, C) and changes in viability (B, D) of RMS cells treated with DMSO (control) or MHPT (5 μM). by Yan Mu (713266)

DataSheet1_The impact of immunotherapies on COVID-19 case fatality rates during the US vaccination campaign: a multidisciplinary open data analysis using FDA Adverse Event Reportin... by Anke Salmen (5321717)

<i>C. burnetii</i> utilizes α_Vβ₃ integrin for uptake in a cholesterol-dependent manner. by Stacey D. Gilk (208034)

“…When +cholesterol cells were pre-incubated with vitronectin, the major ligand for a α_Vβ₃ integrin, <i>C. burnetii</i> entry decreased by 66% (p = 0.001) and 71% (p<0.0001) as compared to pre-incubation with fibronectin or BSA, respectively. …”

Effect of costunolide and BIBR1532 on APF mRNA expression by HepG2/C3A and PLC/PRF/5 cell lines. by Roula Tahtouh (714734)

“…The relative mRNA levels were obtained using the Gel Analyzer software. (A) Semi-quantitative reverse transcription- PCR analysis of AFP mRNA in HepG2/C3A cells after treatment with costunolide and BIBR1532 (5 and 10 μM). …”

Image_5_Appetitively motivated tasks in the IntelliCage reveal a higher motivational cost of spatial learning in male than female mice.TIFF by Martina Nigri (12104966)

Image_5_Phytomanagement and Remediation of Cu-Contaminated Soils by High Yielding Crops at a Former Wood Preservation Site: Sunflower Biomass and Ionome.JPEG by Michel J. Mench (5713211)

“…In 2013, one untreated plot (UNT) was amended with a green waste compost (GW, 5%) whereas 12 former OMDL plots received a second compost dressing using this green waste compost (OM2DL, 5%). …”

Image_5_Stimulation of Let-7 Maturation by Metformin Improved the Response to Tyrosine Kinase Inhibitor Therapy in an m6A Dependent Manner.tif by Kai Li (205203)

Image 5_The association between fluid balance trajectories and prognosis in ICU patients with cardiac arrest, a group-based trajectory model analysis.tif by Qitian Zhang (19791372)