DataSheet_1_MiR-4270 acts as a tumor suppressor by directly targeting Bcl-xL in human osteosarcoma cells.pdf by Clément Veys (16910898)

“…The antiproliferative and cytotoxic effects of miRNAs were evaluated in comparison with a positive control, miR-342-5p. The cytotoxic effect of four selected miRNAs was not confirmed on SW1353 cells, but we unambiguously revealed that miR-4270 had a potent cytotoxic effect on HOS and MG-63 osteosarcoma cell lines, but not on SaOS-2 cell line. …”

Experimental design and results for Experiment 5: Face inversion effect (FIE). by Meike Ramon (2578348)

Related to Fig 1. by Mohammad Nafees Ansari (22232505)

“…(<b>J</b>–<b>M</b>) Immunoblot confirms silencing of UGCG in MCF-7 and BT-474 cells (J, L) and cell proliferation assay demonstrates a decrease in proliferation in MCF-7_UGCG^SL and BT-474_UGCG^SL cells over MCF-7_SCRAM^SL (mean ± SEM, <i>n</i> = 5) and BT-474_SCRAM^SL cells (mean ± SEM, <i>n</i> = 3) (K, M). …”

Luminal tumors have a deregulated sphingolipid and ganglioside profile and high RICTOR expression. by Mohammad Nafees Ansari (22232505)

“…(<b>D</b>–<b>H</b>) Absolute quantification (mean ± SEM, <i>n</i> = 5) of GM3 (D), GD3 (E), GD2 (F), GM2 (G), and GM1 (H) gangliosides in luminal tumor tissues and adjacent normal tissues shows an increase in GM3 and GD3 gangliosides and a decrease in GM1 gangliosides in luminal tumor tissues. …”

PG increased the number of necrotic cells in HepJ5 cells. by Po-Li Wei (292225)

“…<p>The percentage of viable and necrotic cells was measured by high-content analysis at specific time intervals. (A) PG exposure caused a dramatic decrease in HepJ5 cell viability after 24 h. …”

Projected change in importance value for dominant species in five broad assemblages. by Jennifer K. Costanza (4416976)

Autophagic machinery is involved in cross-over endocytosis. by Nora Gehne (4357123)

“…<p><b>A</b>: Cocultures of mTurquoise2 (TRQ)-Cldn5 or LC3 labeled with red and green fluorescent protein (RFP-GFP-LC3) mono-transfected in Madin-Darby canine kidney cells II (MDCK-II). …”

Butyrylation Meets Adipogenesis-Probed by a p300-Catalyzed Acylation-Specific Small Molecule Inhibitor: Implication in Anti-obesity Therapy by Aditya Bhattacharya (4499686)

“…Treatment of 3T3L1 cells with LTK-14A abolished adipogenesis with downregulation of pro-adipogenic genes along with inhibition of H4K5 butyrylation. …”

Butyrylation Meets Adipogenesis-Probed by a p300-Catalyzed Acylation-Specific Small Molecule Inhibitor: Implication in Anti-obesity Therapy by Aditya Bhattacharya (4499686)

“…Treatment of 3T3L1 cells with LTK-14A abolished adipogenesis with downregulation of pro-adipogenic genes along with inhibition of H4K5 butyrylation. …”

Effect of rec.5S rRNA expression on the heteroplasmy level of KSS mutation. by Romuald Loutre (5410142)

“…<p>(<b>a</b>) Proportion of KSS mtDNA (Y axis) in cybrids cell lines with low expression of rec.5S rRNA versions (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0199258#pone.0199258.t001" target="_blank">Table 1</a>) after 8 weeks of cultivation in high glucose or glucose-free media, as indicated. …”

Inhibitors of 5-LOX block TRPM7-mediated cell rounding. by Hsiang-Chin Chen (247146)

“…<p>(A) Application of the 5-LOX inhibitors NDGA (10 µM), AA861 (10 µM), and MK886 (10 µM) to 293-TRPM7 expressing cells reduced cell rounding. …”

Susceptibility to COPD: Differential Proteomic Profiling after Acute Smoking by Lorenza Franciosi (600602)

“…SerpinB3 and Uteroglobin decreased after acute smoke exposure in young non-susceptible individuals exclusively, whereas Peroxiredoxin I, S100A9, S100A8, ALDH3A1 (Aldehyde dehydrogenase 3A1) decreased both in young susceptible and non-susceptible individuals, changes being significantly different between groups for Uteroglobin with iTRAQ and for Serpin B3 with iTRAQ and ELISA measures. …”

Inhibition of Cdk5 Activity Attenuates Dendritic Spine Formation and Maturation by Sebastian Jessberger (269496)

“…</p> <p>(B) Inhibition of cdk5 activity did not affect the formation but decreased the maturation of dendritic spines on apical dendrites of <i>DNcdk5</i>-expressing granule cells, whereas <i>DNcdk5</i>-expressing neurons with aberrantly targeted basal dendrites (BasalDNcdk5) showed a decrease in both formation and maturation of dendritic spines. …”

Related to Fig 3. by Mohammad Nafees Ansari (22232505)

“…(<b>Q</b>) Tumor growth kinetics recorded a significantly higher growth of BT-474_ZFX^OE (mean ± SEM, <i>n</i> = 5) than BT-474_VECT^OE tumors. …”

The relative frequency of AD patients as a function of the concentration of CSF-Aβ42 in subpopulations with low and high amyloid deposition density (amyloid load). by Dmitry V. Zaretsky (14034897)

Human glaucomatous trabecular cells produce SDF-1(5-67). by Alexandre Denoyer (160189)

“…MMP inhibitors batimastat (100 nM) and TIMP-1 (0.5 nM) induce a decrease in SDF-1(5-67) production, whereas TNF-α (50 ng/mL [2.9 nM]) and TGF-β2 (10 ng/mL [0.8 nM]) enhance the production of SDF-1(5-67). ** <i>P</i><0.01. …”

The diagram of RNF5 inhibition on KSHV lytic replication and PEL tumorigenesis. by Xiaojuan Li (351842)

“…In PEL cells with RNF5 silencing, loss, or inhibition (right), RNF5-mediated EphA3 and EphA4 ubiquitination and degradation are inhibited, and the levels of EphA3 and EphA4 are increased, probably facilitating dimerization and oligomerization, which decrease ERK and Akt activation and the expression of cell cycle CDK1 and hedgehog gene Smo, resulting in the inhibition of KSHV lytic replication and suppression of PEL growth.…”

Differentiation of SY5Y on PA6 under optimised conditions. by Ross Ferguson (3155448)

Schematic representation of key responses to MERS-CoV related to outcome. by Emmanuel Faure (391756)

“…Right panel: In the absence of recognition, the decrease in IRF 3 is associated to a decreased production of IL 12 and IFNγ. …”

LTP modulates steady-state inactivation of A-type K⁺ currents. by Sung-Cherl Jung (261358)

“…Scale bars, 200 pA, 50 ms. The A-current available for activation at −60 mV was significantly decreased only in the neurons receiving paired stimulation 10 min after conditioning stimulation (a red arrow). …”