In vitro studies on effect of Cisplatin and paclitaxel on PIK3CA promoter and p53. by Snehal M. Gaikwad (279479)

“…A dose dependent decrease in luciferase activity (<i>PIK3CA</i> promoter activity) was observed on increasing concentrations of cisplatin treatments in PPF cells (at 3 & 5 µg/ml cisplatin, p<0.03) (2a) and in APFT cells at 20 and 30 µg/ml cisplatin (p<0.003) (2c). …”

DataSheet2_Changes in Organic Matter Deposition Can Impact Benthic Marine Meiofauna in Karst Subterranean Estuaries.pdf by David Brankovits (10793055)

“…These patterns suggest that a reduction in the local mangrove habitat decreased the terrestrial particulate OM input to the cave over time. …”

Image_1_Tumor Suppressive Maspin-Sensitized Prostate Cancer to Drug Treatment Through Negative Regulating Androgen Receptor Expression.TIF by Sijie Tang (8494560)

“…In the current study, treatment of 5′-Aza or MS-275/enzalutamide induced poly (ADP-ribose) polymerase (PARP) cleavage and p-H2A.X in CaP cells with an increase of maspin expression but a decrease of AR. …”

Image_2_Tumor Suppressive Maspin-Sensitized Prostate Cancer to Drug Treatment Through Negative Regulating Androgen Receptor Expression.TIF by Sijie Tang (8494560)

“…In the current study, treatment of 5′-Aza or MS-275/enzalutamide induced poly (ADP-ribose) polymerase (PARP) cleavage and p-H2A.X in CaP cells with an increase of maspin expression but a decrease of AR. …”

Intestinal enteroids recapitulate the effects of short-chain fatty acids on the intestinal epithelium by Sarah C. Pearce (8661816)

“…Gene expression of <i>Lgr5</i> was shown to decrease with BUT and PROP treatments, but increased with ACET. …”

Knockdown of α-actinin-2 increases spine number and inhibits spine maturation. by Jennifer L. Hodges (207936)

“…Overexpression of α-actinin-2-SS increases spine length (F) and reduces spine head width (G). α-Actinin-2-SS overexpression creates an increase in the fraction of filopodia-like spines and a decrease in the fraction of stubby spines, H. …”

Table_1_Pediatric Obesity and Eating Disorders Symptoms: The Role of the Multidisciplinary Treatment. A Systematic Review.docx by Rachele De Giuseppe (6550565)

“…Two studies found a significant decrease of binge eating symptoms and other two studies showed an improvement of self-perception, weight, and shape concern. …”

Gene function in early mouse embryonic stem cell differentiation-4 by Kagnew Hailesellasse Sene (25572)

Effect of polymer composition. by Yi Bao (278186)

“…Data are presented as mean ± SEM; N > 3. We examined the effect of polymer composition on NPs using acetonitrile to dissolve different mass ratios of PLGA(M) with PEG-PLGA at 5 mg/mL concentration, TFR = 300 μL/min, and FRR = 5. …”

Phase I mRNA components are significantly reduced in several newborn tissues in the absence of pRb. by Maria Teresa Sáenz Robles (201330)

“…Adh levels are used as endogenous controls. b) RNAs from newborn tissue samples were analyzed by Real time PCR, indicating that Cyp3A11 and Cyp3a25 mRNAs decrease substantially in samples lacking a functional RB gene in all tissues tested: liver; small intestine and lungs. …”

VAPB is required for tumor growth <i>in vivo</i>. by Meghana Rao (130226)

“…Tumors were harvested 5 weeks after transplantation. Tumor size was measured by a caliper and tumor volumes were calculated. …”

Mu and delta opioid receptor expressing interneurons are recruited by the TA pathway. by Xavier Rezai (5656768)

“…<p>TA-eIPSCs amplitude is decreased following DAGO 500 nM (A) or deltorphin II 500 nM (B) bath application in DOR-eGFP knock-in mice. *, p<0.05, **, p<0.01 versus baseline or drug respectively. …”

Modeling experimental findings on lamotrigine application. by Michele Migliore (323322)

“…<p>(<i>left</i>) experimental recordings demonstrating a decrease in dendritic (but not somatic) firing after <i>I_h</i> up-regulation caused by application of the anticonvulsive drug Lamotrigine (adapted from Fig. 2d of <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0036867#pone.0036867-Poolos1" target="_blank">[4]</a>); (<i>right</i>) simulation of somatic (<i>bottom</i>) and dendritic (<i>top</i>, ∼200 µm from soma) recordings during a 500 ms current injection of 0.55 or 0.82 nA, respectively, before (control) and during LTG application (bar above plots); <i>g_{h_pk}</i> = 0.01 mS/cm², <i>lk</i> = 0.5 (control), <i>lk</i> = 0.8 (LTG).…”

Contrasted adaptive responses of different <i>Medicago truncatula</i> genotypes to nitrogen availability. by Anouk Zancarini (126528)

“…Group 1 includes DZA315-16 and DZA315-26; Group 2 includes F83005-5 and SA028064; Group 3 includes Jemalong-A17, Jemalong-J6. …”

Histopathology of the hippocampus seven days following Sham or ACA. by Charles H. Cohan (733750)

“…<b>B)</b> Bar graph depicting the number of non-compromised neurons per field to left (LH) or right (RH) hemisphere to their respective groups, where there was a significant decrease in the number non-compromised neurons following ACA in the CA1 region and RH of the subiculum (*<i>p</i><0.05; Sham n = 6 and ACA n = 5).…”

Echocardiography analysis was followed up to 6 weeks of reperfusion to examine the chronic effects of IR injury. by Megumi Eguchi (333410)

“…On the contrary, STZ mice developed concentric hypertrophy as shown by decreased LVEDV, LVESV and increased EF (A,B,C). M-mode image showing the increase in the LV wall and decrease in interstitial space in STZ heart (D). …”

Receptive fields of two neurons in the optic tectum. by Josine Verhaal (400568)

“…The neuron responded with a short delay to black (40 ms) and with a longer delay to white (130 ms) and therefore could be responsive to decrease in luminance. …”

Sequential Injection Analysis of Butyrylcholinesterase Using Butyrylcholine Ion-Selective Electrode Detector (Supporting Information) by Narimasa KOIZUMI (13719592)

“…In the present SIA method using the BuCh-ISE detector based on <i>α</i>-cyclodextrin membrane, BChE in the concentration range of 0.015–0.50 units/mL was determined at a BuCh concentration of 2.0 mmol dm⁻³ and a reaction time of 5.0 min. …”

Naloxone does not block loperamide effects on mechanosensitivity of C-fibers. by Matthias Ringkamp (253465)

“…<p>A) Naloxone pretreatment does not prevent the loperamide (5 µg/10 µl) – induced increase in mechanical thresholds of C-fibers. …”

(Left) The recorded path of 2 coral larva specimens in the olfactometer. by Spencer J. Franks (22320384)

“…<p>Positions are recorded at 5 Hz, and the coordinates are graded in millimeters. …”