Integrating Functional Data to Prioritize Causal Variants in Statistical Fine-Mapping Studies by Gleb Kichaev (652009)

“…We validate our findings using a large scale meta-analysis of four blood lipids traits and find that the relative probability for causality is increased for variants in exons and transcription start sites and decreased in repressed genomic regions at the risk loci of these traits. …”

Paired Box Gene 6 Regulates Heme Oxygenase-1 Expression and Mitigates Hydrogen Peroxide-Induced Oxidative Stress in Lens Epithelial Cells by Yuxing Zheng (13849916)

“…The decrease of Pax6 weakened the antioxidant ability of LECs under H₂O₂-induced oxidative stress by downregulating HO-1, which may be a potential mechanism for the formation of age-related cataract.…”

Flow diagram for generation of ZFN mutants, and HRMA analysis. by Lingyan Xing (310457)

“…(B) Illustrative melt-curve (“HRMA” high-resolution melt analysis) of F1 generation <i>foxP2</i> ZFN fish. Y-axis corresponds to the differential of the change (decrease) in fluorescence; X-axis is the temperature (°C). …”

Use of viscoelastic substance for preventing Descemet’s membrane rupture in deep anterior lamellar keratoplasty by Yusuf Koçluk (5761517)

“…Conclusions: Administering a viscoelastic substance onto the posterior stromal side just before puncture is an effective method to decrease the risk of Descemet’s membrane perforation in deep anterior lamellar keratoplasty.…”

DNA methylation standards for SALL3 () and TWIST2 () by Romulo Martin Brena (14620)

“…As the methylation percent of the sample increases, there is a decrease in the fluorescence of the 208 bp peak and an increase in the fluorescence of the digested peaks (75% versus 87.5% plots). …”

Body image among adolescents: the association between nutritional status and physical activity by Edmar Roberto Fantineli (10400253)

“…The association between nutritional status and level of physical activity with satisfaction with body image was performed through multinomial logistic regression to obtain the odds ratio with a 95% confidence interval and p < 0.05. Overweight/obesity was positively associated with moderate and severe body image dissatisfaction (BID) among girls (OR: 6.20; 95%CI: 2.62 - 14.66 and OR: 6.20; 95%CI: 4.10 - 9.36) and boys (OR: 1.95; 95%CI: 1.06 - 3.59 e OR: 3.91; 95%CI: 2.57 - 5.95) and with the desire to decrease the silhouette for boys and girls (OR: 4.86; 95%CI: 3.37 - 7.00 and OR: 6.46; 95%CI: 4.12 - 10.14). …”

Chemical structure and anti-cancer activities of Etoposide and C-10 on breast cancer cells. by Chatla Srinivas (823944)

“…(B) Trypan blue assay for cell viability on MCF-7 and MDA-MB-231 cells showing gradual decrease in viability after treatment with Etoposide or C-10 at 1–16 μM or Cisplatin at 5–40 μM and incubated for 24 h. …”

External effective doses from soil samples due to artificial radionuclides in the Semipalatinsk Nuclear Testing Site and Chagan (Kazakhstan). by Yasuyuki Taira (305653)

“…</i></p><p>where <i>C</i> is the activity concentration of detected artificial radionuclides (²⁴¹Am, ¹³⁷Cs and ⁶⁰Co; halh-life > 1y) (kBq/m²; calculated from radionuclide concentration in Bq/kg and collected areas of soils (0–5 cm)), <i>D_ext</i> is the dose conversion coefficient as kerma-rate in air at 1 m above ground per unit activity per unit area ((µGy/h)/(kBq/m²) for detected artificial radionuclides with the value of relaxation mass per unit area 10 g/cm² (ICRU 1994)), <i>f</i> is the unit conversion coefficient (0.7 Sv/Gy (UNSCEAR 2000)), <i>s</i> is the decrease in the coefficient by a shielding factor against exposure with gamma rays from a deposit at 1 m above ground (0.7 under the condition of usual land (IAEA-TECDOC-1162)).…”

The effect of phasic dynamics are robust to noise statistics and linearly related to expression. by Margot C. Bjoring (6269591)

“…<p>(A—D) The effect of varying signal-to-noise ratios (SNR) on the outcome of the total entropy (A), noise entropy (B), MI (C), and selectivity (D) analyses. …”

DP-b99 diminishes neurodegenerative effect of kainate in hippocampal slice cultures. by Marine Yeghiazaryan (576485)

“…<p><b>A</b> – Representative fluorescence photomicrographs of organotypic hippocampal slices (16 DIV) showing uptake of PI 24 h after various treatments: CTRL (untreated cultures); DP-b99 20 µM and 0.12 µM; KA (5 µM); KA+DP-b99 20 µM or 0.12 µM. …”

Exogenous enzymes improve performance and carcass traits of feedlot cattle fed high-grain diet by Mikael Neumann (4869517)

“…There was an increase in apparent dry matter digestibility and a decrease of fecal whole grain residual percentage with enzyme supplementation. …”

Proliferation of HBO-treated cells. by Jennifer Schulze (2502799)

“…By contrast, the proliferation of MSCs started to decrease after five consecutive HBO treatments with 2.0 bar until the end of ten treatments in comparison to NOR. …”

Enhancement of the Photodegradative Potential of Polymer Composites Containing Babassu Fiber by Josélia Borges de Moura Furtado (10443249)

“…The fibers were extracted manually and immersed in a 10% NaOH solution (Mercerization). After drying, they were crushed and incorporated into the low-density polyethylene matrix in proportions of 5%, 10%, and 20% of the total mass of the composite. …”

Clinical and virological profiles of ponies inoculated with the consensus Env in attenuated (ConD9) and pathogenic (EVCon) EIAV viral backbones. by Jodi K. Craigo (421284)

“…Febrile episodes were defined by a combination of two-three features, including: rectal temperature above 39°C in conjunction with thrombocytopenia (platelet decrease of ≥70,000/µl of whole blood), EIAV viral load ≥10⁵ as well as other clinical signs of EIA.…”

MODELING AND SIMULATING LAND USE/COVER CHANGE USING ARTIFICIAL NEURAL NETWORK FROM REMOTELY SENSING DATA by Ender Buğday (7366931)

“…Using the exponential rate of change; the population was predicted to increase by concentrating on the urban area and the rural areas surrounding the urban (with a rate of 2.019%) for 2027. According to the results; rural population, urban population, forest, and built-up areas is estimated to increase by 4.14%, 5.58%, 2.72%, and 0.77% respectively from 2017 to 2027, while the agricultural and water area is estimated to decrease by 3.47% and 0.02% respectively. …”

Interaction of Nanoparticles with Multidrug-Resistant Bacteria by Raman Preet Singh (1918336)

Molecular mechanism of the AR-induced senescence. by Yelena Mirochnik (179447)

“…<p>This figure summarizes our findings. (<b>A</b>) mTOR activity in PC3-AR cells. Cells were treated with Dox alone (D) or in combination with DHT. …”

Geographically closed, yet so different: Contrasting long-term trends at two adjacent sea turtle nesting populations in Taiwan due to different anthropogenic effects by I-Jiunn Cheng (384638)

“…The decrease of the nesting population on Wan-an Island might be due to illegal poaching on the high seas along the migratory corridor of the turtles, whereas the stable nesting population on Lanyu Island showed no evidence of such a threat. …”

Low dissolved oxygen levels increase stress in piava (Megaleporinus obtusidens): iono-regulatory, metabolic and oxidative responses by CARLOS E. COPATTI (7291634)

“…Fish were exposed to different DO levels, including 1.0, 2.0, 3.0, 4.0 and 5.0 mg L-1 of DO for 96 h, after which blood and tissue samples (liver, kidney, gill and muscle) were collected. …”

Hsp90 Promotes the Disassembly of Preformed rTDP-43 Filaments. by Yari Carlomagno (152800)

“…These preformed TDP-43 filaments were then incubated with increasing concentrations of Hsp90 and samples were assayed using Image Pro Plus from 0–16 hours. A) As rapidly as the Hsp90 could be added and the grids prepared for EM, the T = 5 minute measurements show the number of TDP-43 filaments was significantly reduced, and B) this translated into a robust dose dependent decrease in the total filament mass recorded per field. …”