In vitro BACE-activity assay on palAPP-dimers in detergent resistant membranes (DRMs). by Raja Bhattacharyya (3359186)

DataSheet_1_Icanbelimod (CBP-307), a next-generation Sphingosine-1-phosphate receptor modulator, in healthy men: pharmacokinetics, pharmacodynamics, safety, and tolerability in a r... by Jason Lickliter (18073228)

“…After single-dose 0.5 mg, although a high-fat breakfast versus fasting did not affect maximal decrease, lymphocyte counts tended to be lower after breakfast across most timepoints up to 72 hours. …”

Expression of a misfolded protein changes the landscape of HSC70 binding partners. by Seung W. Ryu (9143069)

“…Summary of proteins identified that increased, decreased, or were statistically indistinguishable in aggregate fraction with SOD1(A4V) expression. …”

hMSCs reduces proliferation of stimulated lymphocytes in a contact-independent manner. by Marilia Normanton (624970)

“…<p>(A–B) A significant proliferation reduction of PHA stimulated lymphocytes (CD3) (38.58±12.39%) assessed by expression of KI-67 was observed in presence of hMSCs (CD3: hMSC) (24.39±12.39%), the same was observed when absolute number KI-67 expressing cells was evaluated decreasing from (3.0×10⁵±1.3×10⁵) up to (1.7×10⁵±0.9×10⁵) (n = 8). …”

Image_1_Can nirmatrelvir/ritonavir treatment shorten the duration of COVID-19 isolation?.pdf by Haein Kim (4839594)

“…Background<p>The impact of nirmatrelvir/ritonavir treatment on shedding of viable virus in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unclear.</p>Methods<p>A prospective cohort study evaluating mildly ill COVID-19 patients was conducted. …”

Global Prevalence of Chronic Kidney Disease – A Systematic Review and Meta-Analysis by Nathan R. Hill (802856)

“…We assessed pooled data using a random effects model. Of 5,842 potential articles, 100 studies of diverse quality were included, comprising 6,908,440 patients. …”

Data_Sheet_1_Creation of a Low-Alcohol-Production Yeast by a Mutated SPT15 Transcription Regulator Triggers Transcriptional and Metabolic Changes During Wine Fermentation.PDF by Qing Du (1610224)

“…Here the global transcription machinery engineering (gTME) technology was used to engineer a yeast strain with decreased ethanol yield, based on the mutation of the SPT15 gene. …”

A mechanistic mathematical model of HIV primary infection including VRC01. by Daniel B. Reeves (8407932)

“…The presence of VRC01 reduces free virus <i>V</i>_<i>f</i>. B) Best-fit models of natural HIV dynamics (without VRC01) using data from the RV 217 trial [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1007626#pcbi.1007626.ref023" target="_blank">23</a>] demonstrates satisfactory fit to heterogeneous viral-load kinetics. …”

Supplementary Material for: A Novel Mutation in Insulin-Like Growth Factor 1 Receptor (c.641-2A>G) Is Associated with Impaired Growth, Hypoglycemia, and Modified Immune Phenotypes by Shapiro M.R. (9572729)

Clinicopathological features and postoperative prognosis of invasive mucinous adenocarcinoma: a retrospective study by Tengteng Wang (14288480)

“…However, 5-year overall survival of the IMA group was significantly decreased. …”

Representative changes of tumor size and necrosis size with attenuation on first follow-up contrast-enhanced computed tomography (CT) scans in metastatic renal cell carcinoma (RCC)... by Sung Han Kim (512136)

“…<p>A. Axial CT image before sunitinib therapy showed a 14.5 cm-sized enhancing left renal mass with hilar invasion and presence of venous tumor thrombi. …”

DataSheet_1_The effect of G0S2 on insulin sensitivity: A proteomic analysis in a G0S2-overexpressed high-fat diet mouse model.pdf by Dongming Wu (11619167)

“…</p>Methods<p>In this study, we extracted livers from mice that consumed HFD and received tail vein injections of AD-G0S2/Ad-LacZ, and performed a proteomics analysis.</p>Results<p>Proteomic analysis revealed that there was a total of 125 differentially expressed proteins (DEPs) (56 increased and 69 decreased proteins) among the identified 3583 proteins. …”

Table 2_The effect of treatment with a non-ionic surfactant vesicular formulation of sodium stibogluconate on host immune responses and serum metabolites in a murine model of Leish... by Raphael Taiwo Aruleba (12011345)

“…</p>Methods<p>BALB/c mice infected with L. donovani were divided into cured and non-cured groups based on treatment with a non-ionic surfactant vesicle formulation of sodium stibogluconate (300 mg Sb^v/kg, SSG-NIV) or PBS vehicle control. …”

Supplementary Material for: Ruyi Zhenbao Tablet and Baimai Ointment Therapy in Acute Ischemic Stroke: A Study Protocol for a Multi-center, Randomized, Double-blinded, and Parallel... by Qin X. (3237450)

Table 1_The effect of treatment with a non-ionic surfactant vesicular formulation of sodium stibogluconate on host immune responses and serum metabolites in a murine model of Leish... by Raphael Taiwo Aruleba (12011345)

“…</p>Methods<p>BALB/c mice infected with L. donovani were divided into cured and non-cured groups based on treatment with a non-ionic surfactant vesicle formulation of sodium stibogluconate (300 mg Sb^v/kg, SSG-NIV) or PBS vehicle control. …”

10 μM βE2 pretreatment for 0.5 hrs protected primary cultured SD rat retinal cells from apoptosis induced by 100 μM H₂O₂ treatment for 24 hrs. by Yan Feng (128912)

“…<p>The PI3K/Akt pathway mediated this process, but the alteration in [Ca²⁺]_i was undetectable. A: The Annexin V/Propidium Iodide staining apoptosis assay; B: Quantitative data of A; C and D: Cell viability and [Ca²⁺]_i quantitative data; 10 μM βE2 pretreatment for 0.5 hrs significantly restored the decrease in cell viability and apoptosis, which was significantly inhibited by 10 μM LY (B, C), but the [Ca²⁺]_i was not significantly altered in all treated groups (D); E: Western blot results, 10 μM βE2 pretreatment for 0.5 hrs promoted p-Akt level, which was inhibited by 10 μM LY pretreatment for 0.5 hrs before βE2 and H₂O₂ co-treatment. …”

<i>KIR2DL2</i> in HCV infection: <i>KIR2DL2</i> enhances the protective effect of <i>HLA-B*57</i> on HCV status (spontaneous clearance v chronic infection) and, independently, on H... by Nafisa-Katrin Seich al Basatena (201133)

Risk of AVF-occlusion after surgery. by Clemens Grupp (7411073)

Influence of Ocean Acidification on a Natural Winter-to-Summer Plankton Succession: First Insights from a Long-Term Mesocosm Study Draw Attention to Periods of Low Nutrient Concent... by Lennart T. Bach (520701)

“…<div><p>Every year, the oceans absorb about 30% of anthropogenic carbon dioxide (CO₂) leading to a re-equilibration of the marine carbonate system and decreasing seawater pH. …”

DataSheet_1_Evaluation of the immunomodulatory effects of interleukin-10 on peripheral blood immune cells of COVID-19 patients: Implication for COVID-19 therapy.docx by Saeid Najafi-Fard (13719727)

“…Here we investigated the impact of IL-10 in COVID-19, through the ex-vivo assessment of the effects of exogenous IL-10 on SARS-CoV-2-specific-response using a whole-blood platform.…”