DataSheet1_Inhibition of colon cancer K-RasG13D mutation reduces cancer cell proliferation but promotes stemness and inflammation via RAS/ERK pathway.PDF by Yan Qi (59532)

“…We found a close correlation of increased Lgr5 and CD133 with proinflammatory factors like IL-17, IL-22, and IL-23. …”

Validation and characterization of the inverted <i>in vitro</i> model of human FAE. by Nicolas Rochereau (368651)

“…<p>(a) Schematic representation of the successive steps leading to the establishment of the M-like cell-containing Caco-2 cell monolayer. …”

Summary of results for hub identification and hub classification for high-degree areas in macaque cortex. by Olaf Sporns (2645)

“…<p>Measures listed under ‘hub identification”: <i>k</i> = degree (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0001049#pone-0001049-g002" target="_blank">Figure 2</a>),  = z-score relative to random and lattice controls (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0001049#pone-0001049-g003" target="_blank">Figure 3</a>), <i>ap</i> = apex ratio (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0001049#pone-0001049-g005" target="_blank">Figure 5A</a>), <i>γ</i> = clustering coefficient (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0001049#pone-0001049-g005" target="_blank">Figure 5B</a>),  = betweenness centrality (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0001049#pone-0001049-g006" target="_blank">Figure 6A</a>),  = closeness centrality (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0001049#pone-0001049-g006" target="_blank">Figure 6B</a>). …”

HOXA2 control of target enhancers. by Laure Bridoux (481118)

“…Heatmap shows <i>Meis2 and Zfp703</i> expression in E11.5 mouse BA1, BA2 and PBA, based on the normalized expression values CPM [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009162#pgen.1009162.ref030" target="_blank">30</a>]. …”

Serum Levels of Acyl-Carnitines along the Continuum from Normal to Alzheimer's Dementia by Adriana Cristofano (2795584)

“…The concentrations of acetyl-L-carnitine progressively decreased passing from healthy subjects group (mean±SD, 5.6±1.3 μmol/L) to subjective memory complaint (4.3±0.9 μmol/L), mild cognitive impairment (4.0±0.53 μmol/L), up to Alzheimer’s disease (3.5±0.6 μmol/L) group (p<0.001). …”

Structure diagram of mobile and hitching base. by Liang Ge (541067)

“…The experimental results show that: (1) The liquid volume in a tank of vacuum degree within 2.0 Pa and 200 mm interlayer reduced no more than 15.5% after 48 days; (2) Taking the pressure in the tank as the power source, because of environmental differences inside and outside the pipe after 100 m pressure holding delivery, the physical form of liquid and gas could be converted instantly; (3) The continuous discharge time without ice blocking for a tank full of 2 m³ liquid was about 10.5 min under 25 L dual mode nitrogen pressurization, which is 1/12 of injection time after ground gasification; (4) Based on the temperature decrease trend measured at different positions, the cooling characteristics on liquid gasification jet path are quantified, and the calculation formula of temperature changing with time on the center line of liquid gasification jet is obtained. …”

Supplementary Material for: Immune Synaptopathy and Sex Differences in Recognition Memory from Neonatal Staphylococcus epidermidis Infection by figshare admin karger (2628495)

“…At the cellular level, both sexes displayed a significant decrease in doublecortin-positive (DCX⁺) neurons in the dentate gyrus after SE infection, indicating impaired neuroplasticity. …”

Association of insulin receptor substrate 1 (<i>IRS-1</i>) gene polymorphism with growth and litter-related traits in NMER rabbits by Naglaa Fathy Megahed (16323949)

“…These genotypes displayed a marked low <i>F_IS</i> value. Significant associations of the genotypes with the body weights, and gains, except at the 5^th week old determined with superiority of the GT genotype compared with the other genotypes. …”

NTS_QECH by Catherine Wilson (8586315)

“…Over this period, 26 confirmed cases of<i> Salmonella</i> meningitis were recorded (88.5% <i>S.</i> Typhimurium). Between 2011-2019 there was a substantial decrease in proportion of <i>S.…”

Overexpression of virally down-regulated genes impairs WNV infectivity. by Tonya M. Colpitts (177569)

“…<p>A. Overexpression of DDRGs reduces WNV infection of <i>Ae. aegypti</i> mosquito cells. …”

Combined expression of pTFs promotes transdifferentiation efficiency, however only their sequential expression increases β-cell maturation. by Dana Berneman-Zeitouni (519463)

“…<p>Cultured adult human liver cells were infected with <i>Ad-CMV-Pdx1</i> (1000 MOI), <i>Ad-CMV-Pax-4</i> (100 MOI) and <i>Ad-CMV-Mafa</i> (10 MOI) together or in a sequential manner as summarized in (A) (treatments B–E) or with control virus (<i>Ad-CMV-β-gal</i>, 1000 MOI, treatment A), and analyzed for their pancreatic differentiation six days later. …”

Table1.docx by Yan Liu (25061)

“…However, few studies stem from the perspective of whole transcriptome change in a fish brain and its response to long-term hypersaline stress. …”

Motor function impairment in the three stroke models. by Oliver Schmitt (159300)

“…Gait parameters were assessed at preoperative (d0) and 5 weeks (d5w) after left stroke surgeries. All three parameters had no difference among the four groups before stroke surgery, but five weeks after stroke surgery, the sMCAO rats presented very severe gait impairments compared to the sham rats, especially the impairments of paw intensity and maximal area. …”

Supplementary Material for: Effect of frail phenotype on cardiorenal risk and healthcare utilization in older patients with chronic kidney disease by Sun C.-Y. (10070377)

“…Frailty phenotype consists of shrinking, low activity, exhaustion, weakness, and slowness, scored 0 to 5. The primary composite renal outcome was a ≥ 25 % decrease in eGFR concurrent with CKD stage progression or dialysis initiation. …”

The effect of green coffee extract supplementation on obesity indices: critical umbrella review of interventional meta-analyses by Zhao Yang (358244)

“…<p>Despite a multitude of investigations assessing the impact of green coffee extract supplementation on obesity indices, there is still a great deal of heated debate regarding the benefits of this intervention in obesity management. …”

Cycling Promotion and Non-Communicable Disease Prevention: Health Impact Assessment and Economic Evaluation of Cycling to Work or School in Florence by Cristina Taddei (732582)

“…</p><p>Results</p><p>Increasing cycling modal share in Florence from 7.5% to about 17% (Scenario 1) or 27% (Scenario 2) could decrease the incidence of type 2 diabetes by 1.2% or 2.5%, and the incidence of acute myocardial infarction (AMI) and stroke by 0.6% or 1.2%. …”

Data_Sheet_1_Changes in Sexuality and Quality of Couple Relationship During the COVID-19 Lockdown.CSV by Marta Panzeri (482188)

“…However, some female participants did report a decrease in pleasure, satisfaction, desire, and arousal. …”

HIV-1 Replication Fitness of HLA-B*57/58:01 CTL Escape Variants Is Restored by the Accumulation of Compensatory Mutations in Gag by Esther F. Gijsbers (465283)

“…Escape mutations in CTL epitopes restricted by these HLA alleles come at a fitness cost and particularly the T242N mutation in the TW10 CTL epitope in Gag has been demonstrated to decrease the viral replication capacity. …”

Table_1_Monitoring Coxiella burnetii Infection in Naturally Infected Dairy Sheep Flocks Throughout Four Lambing Seasons and Investigation of Viable Bacteria.XLSX by Raquel Álvarez-Alonso (8038580)

“…Real-time PCR analyses showed different trends in C. burnetii shedding in the flocks, with a general progressive decrease in bacterial shedding throughout the years, interrupted in three flocks by peaks of reinfection associated with specific management practices. …”

Table_2_Monitoring Coxiella burnetii Infection in Naturally Infected Dairy Sheep Flocks Throughout Four Lambing Seasons and Investigation of Viable Bacteria.XLSX by Raquel Álvarez-Alonso (8038580)

“…Real-time PCR analyses showed different trends in C. burnetii shedding in the flocks, with a general progressive decrease in bacterial shedding throughout the years, interrupted in three flocks by peaks of reinfection associated with specific management practices. …”