Polyheteroaryl Oxazole/Pyridine-Based Compounds Selected in Vitro as G‑Quadruplex Ligands Inhibit Rock Kinase and Exhibit Antiproliferative Activity by Daniela Verga (2202436)

“…Herein, we report on the synthesis of parent compounds bearing either amino side chains (TOxaPy-1–5) or featuring an isomeric oxazole-pyridine central connectivity (iso-TOxapy, iso-TOxapy 1–3) or a bipyridine core (iso-TOxabiPy). …”

Acute effects of different intensities and amounts of aerobic exercise on the concentrations of tryptophan and serotonin in physically active elderly women by Jônatas de França Barros (4657306)

“…For this, 49 older women (aged 60 to 75 years) physically active were divided into six groups: being a control group (CG, n = 8) and five experimental groups: 1) aerobic exercise performed at 90% of ventilatory threshold (VT90, n = 8); 2) intensity exercise performed at ventilatory threshold (VT, n = 8); 3) intensity exercise performed on 90% of the respiratory compensation point (RCP90, n = 8), each with lasting 20 min; 4) maximal incremental test (MIT, n = 8); and 5) exercise held in ventilatory threshold intensity with lasting 60 min (VT60min, n = 9). …”

Long-term trends of potential years of life lost due to main causes of death in the Slovak population, 2004-2013 by Martin Samohyl (10388448)

“…The PYLL rates trend regarding external causes of morbidity and mortality showed the most notable decrease in the assessed period and the AAPC of PYLL showed significant negative values both in males (-2.5%; p < 0.001) and females (-4%; p < 0.001). …”

Data Sheet 1_Study on the function of TTG1 gene in Camellia oleifera.docx by Chengcheng Xiang (5512442)

“…In this study, we isolated the CoTTG1 gene from C. oleifera, which encodes a nuclear-localized protein (molecular weight 38.38 kDa, pI 5.0) sharing 99.71% sequence identity with Camellia japonica TTG1. …”

Characterization of <i>ob/ob</i>-luc mice. by Manishkumar Patel (627143)

“…<p>A) Weight increases significantly with age in <i>ob/ob</i>-luc mice consistent with the original <i>ob/ob</i> mouse model on the B6 black background. …”

Data_Sheet_1_Genome-Wide Profiling of DNA Methylome and Transcriptome Reveals Epigenetic Regulation of Potato Response to DON Stress.PDF by Yan Shi (166398)

“…However, potato production is affected by numerous biotic and abiotic stresses, among which Fusarium dry rot is a disease that has significant effect on potato production, storage, and processing. …”

Effects of JAK inhibitors, AG-490 and WHI-P154, on IFN-γ-induced iNOS mRNA expression and degradation in J774 macrophages by Outi Sareila (66176)

“…</p><p>Published online 19 Mar 2006</p><p>PMCID:PMC1592588.</p><p></p> (a) Cells were incubated with IFN-γ (5 ng/mL) in the absence or in the presence of AG-490 and WHI-P154 (10 μM). …”

Image_1_Comparison of the extracellular vesicle proteome between glaucoma and non-glaucoma trabecular meshwork cells.tif by Fiona S. McDonnell (17106334)

“…Introduction<p>Extracellular matrix (ECM) materials accumulate in the trabecular meshwork (TM) tissue of patients with glaucoma, which is associated with a decrease in aqueous humor outflow and therefore an increase in intraocular pressure. …”

Relationship between overrepresentation in Ago2 IP and changes in mRNA levels due to miR-1 and miR-124. by David G. Hendrickson (257868)

“…Red lines correspond to mRNAs that were Ago2 IP targets but did not decrease significantly at the mRNA level; nevertheless, 20 of 22 mRNAs in this group are downregulated (log₂ change<0) at the mRNA level (P<10⁻⁵, one-way binomial test). …”

Data_Sheet_2_Genome-Wide Profiling of DNA Methylome and Transcriptome Reveals Epigenetic Regulation of Potato Response to DON Stress.xlsx by Yan Shi (166398)

“…However, potato production is affected by numerous biotic and abiotic stresses, among which Fusarium dry rot is a disease that has significant effect on potato production, storage, and processing. …”

<i>Fusobacterium nucleatum</i>-Induced Impairment of Autophagic Flux Enhances the Expression of Proinflammatory Cytokines via ROS in Caco-2 Cells by Bin Tang (56654)

“…<i>nucleatum</i> was enhanced with either autophagy pharmacologic inhibitors (3-methyladenine, bafilomycin A1) or RNA interference in essential autophagy genes (ATG5 or ATG12) in Caco-2 cells. …”

Is self-reported 7-day point prevalence abstinence an useful measure for smoking cessation effectiveness among individuals with mental disorders? by Danielle Ruiz Lima (15700468)

“…In this study, it showed that the 6-week smoking cessation treatment had a positive effect among completers, which supports the importance of investing in treatment to decrease smoking prevalence in this population.…”

Primer pairs for RT-qPCR. by Yoichi Kurokawa (22290520)

“…Conversely, exposure to endogenous prooxidants (dopamine and adrenaline), certain food-derived polyphenols (chrysin and 3-<i><i>O</i></i>-methylquercetin), or 1,2-naphthoquinone led to a significant decrease (<0.5-fold) in Rmst expression. …”

Inhibition of DNA Methylation Alters Chromatin Organization, Nuclear Positioning and Activity of 45S rDNA Loci in Cycling Cells of <i>Q. robur</i> by Vedrana Vičić Bočkor (610205)

“…After treatment of the root cells with the methylation inhibitor 5-aza-2′-deoxycytidine, we observed an increase in the total level of rRNA transcripts and a decrease in DNA methylation level at the NOR-2 locus. …”

TbCDC34 activity is modulated by compound CC0651. by Federico Rojas (480253)

“…Samples treated with CC0651 showed a decrease of cells with 1N1K and an increase of cells with 2N2K. …”

Early term ocular changes after cold compress application by Alperen Bahar (6571784)

“…Results: The average age of the participants was 30.74 ± 5.82 years. There was no significant change in the central corneal thickness after cold compress application, and there was a significant decrease in the anterior segment volume (p<0.001), anterior segment depth (p<0.001), and pupil diameter. …”

Additional file 1 of An efficient multiplex approach to CRISPR/Cas9 gene editing in citrus by Cintia H. D. Sagawa (19110809)

“…Supplemental Fig S1: Characterization of RUBY expression in Carrizo citrange shows variation in expression and decrease over time. A Variation of RUBY expression among transformed plants. …”

Effect of subthalamic nucleus lesion on the severity of L-DOPA-induced dyskinesia. by Asier Aristieta (312325)

“…Time course of axial, limb and orolingual AIMs scored in <i>(</i><b><i>C</i></b><i>)</i> STN-lesion and <i>(</i><b><i>D</i></b><i>)</i> STN-sham animal groups. The results show a significant decrease in AIMs scores after STN lesion. …”

Table 1_Global burden of tuberculosis attributable to diet low in whole grains from 1990 to 2021, with projection to 2045.pdf by Xiaoning Lu (206322)

“…</p>Results<p>In 2021, TB-DLWG accounted for 177,303.55 DALYs globally, representing an 8% decrease from 1990. The number of deaths was 5,539.13, a 12% reduction. …”

Table_1_Comparison of the extracellular vesicle proteome between glaucoma and non-glaucoma trabecular meshwork cells.xlsx by Fiona S. McDonnell (17106334)

“…Introduction<p>Extracellular matrix (ECM) materials accumulate in the trabecular meshwork (TM) tissue of patients with glaucoma, which is associated with a decrease in aqueous humor outflow and therefore an increase in intraocular pressure. …”