Identification of Small Molecules that Disrupt Signaling between ABL and Its Positive Regulator RIN1 by Pamela Y. Ting (713174)

“…This assay was used in a high throughput screen (HTS) of two small molecule libraries totaling 444,743 compounds. 708 confirmed hits were counter-screened to eliminate off-target inhibitors and reanalyzed to prioritize compounds with IC₅₀ values below 10 μM. …”

iBAT characterization of the <i>aP2-Drp1</i>^f/f neonatal mice. by Yuta Ibayashi (20404811)

DataSheet_1_Disruptive effects of plasticizers bisphenol A, F, and S on steroidogenesis of adrenocortical cells.docx by Benedikt Pötzl (18854980)

“…However, when combining all three bisphenols, additive effects were detected: e.g. 11-deoxycortisosterone was decreased at doses >10µM (FC 0.27±0.04, p≤0.0001, at 25µM), whereas 21-deoxycortisol was increased by 2.92±0.20 (p≤0.01) at 10µM, and by 3.21±0.45 (p≤0.001) at 50µM. …”

Role of the MAPK pathway in human lung epithelial-like A549 cells apoptosis induced by paraquat by Da-Zhuang Sun (8650728)

Continental-scale effects of selected Δ<em>T</em>_g levels (2 ° C, left bars; 3.5 ° C, middle bars; 5 ° C, right bars), simulated under >50% of the climate change pattern... by Dieter Gerten (557088)

“…The results suggest that already at a Δ<em>T</em>_g of 2 ° C and mainly in the subtropics, higher water scarcity would occur in >50% out of the 19 climate scenarios. …”

Analgesic prescriptions received by patients before commencing the BOA model of care for osteoarthritis: a Swedish national registry study with matched reference and clinical guide... by Allan Abbott (6032138)

“…Since guideline publication, the proportion of the OA cohort having no dispensed prescription analgesics prior to non-pharmacological primary care intervention concordantly increased by 5.0% (95% CI 4.2–5.9). Furthermore, dispensed prescriptions concordantly decreased for non-selective NSAIDs –8.6% (CI –9.6 to –7.6), weak opioids –6.8% (CI –7.7 to –5.9), glucosamine –9.5% (CI –9.8 to –8.8). and hyaluronic acid –1.6% (CI –1.8 to –1.5) but discordantly increased for strong opioids 2.8% (CI 2.1–3.4) and glucocorticoid intra-articular injection for hip OA 2.1% (CI 1.0–3.1).…”

Placental gene expression at E9.5 and E11.5. by Hui Zhao (7395)

Olfactory bulb volume changes associated with trans-sphenoidal pituitary surgery - Fig 2 by Dino Podlesek (710290)

NCOA4 is downregulated in human CCA tissues and is correlated with poor prognosis. by Wenlong Shen (9313937)

Protein synthesis inhibition and EF-2 ADP-ribosylation in KLM-1-R. by Kevin Hollevoet (710450)

Removal of specific N-glycans can alter neutralization potency and completeness. by Sabrina Lusvarghi (2329267)

“…Colors as follow: red, decrease in potency >4-fold; white, no change in IC₅₀ (ratios between 0.25- and 4-fold) and blue increase in potency (ratios <0.25-fold). …”

Transient dynamics of the spiking network and IFA. by Natalie Schieferstein (17996519)

“…Top: Grey dots: discrete instantaneous frequency estimates from 50 repetitions of the simulation shown in (A) with different noise realizations. …”

Structure and growth of the conglobate gland in <i>Blattella germanica.</i> by Viviana Pagone (22086362)

H₂S inhibited the hypotension induced by SO₂ <i>in vivo</i>. by Chufan Sun (3390608)

The impact of socioeconomic status on the utilization of total hip arthroplasty during 1995–2017: 104,055 THA cases and 520,275 population controls from national databases in Denma... by Nina M Edwards (9567542)

Investigation of the role of rosmarinic acid treatment in regulating inflammation, cell damage, and angiogenesis in rat ovarian torsion and detorsion models by Uğur Değer (10393672)

“…Rosmarinic acid was given at a dose of 50 mg/kg by oral gavage three hours after reperfusion. …”

Graphical representation of the adolescent intermittent ethanol (AIE) exposure paradigm. by Ryan P. Vetreno (663148)

Fig 1 - by Melissa A. Hill (13170105)

Analysis of reversibility of acoziborole-resistance. by Pieter C. Steketee (10024552)

The variation of percentage of cells in tumor radius length. by Masoud H. H. Tehrani (8975240)