Validation of the model predictions for mES cell colony-forming efficiencies confirm enhanced self-renewal at reduced oxygen levels with GSK-3 inhibition. by Hélder S. C. Barbosa (158982)

“…Heat-maps show relative expression levels of key pluripotency genes (c), and colonies were stained for Nanog (d.1) or Oct4 (d.2) and nuclear marker DAPI (scale bar: 50 µm). The positive effects of GSK-3 inhibition could be correlated with a decrease in total and phosphorylated protein levels at 20% and 2% O₂ (e). …”

Nuclear Quantum Effects in Sodium Hydroxide Solutions from Neural Network Molecular Dynamics Simulations by Matti Hellström (1886893)

“…Moreover, NQEs significantly lower the proton transfer barriers, thus increasing the proton transfer rates, resulting in an increase of the diffusion coefficient in particular of OH^–, as well as a decrease of the mean residence time of molecules in the first hydration shell around Na⁺ at high NaOH concentrations.…”

Optimization of the Malachite-Green ATPase assay for EHD4^ΔN. by Saif Mohd (19251157)

“…<b>B</b> MLG-based ATPase assays for 4 μM EHD4^ΔN, 500 μg/ml DOPS and 50 μM ATP were done at 37°C and 30°C. A further decrease to 25°C did not affect the enzymatic activity compared to 30°C (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0302704#pone.0302704.s002" target="_blank">S2I Fig</a>). …”

Secreted Amyloid Precursor Protein β and Secreted Amyloid Precursor Protein α Induce Axon Outgrowth In Vitro through Egr1 Signaling Pathway by Stéphanie Chasseigneaux (231744)

“…</p> <h3>Methodology/Principal Findings</h3><p>Final concentrations of 50 to 150 nM bacterial recombinant sAPPα or sAPPβ added to primary neuronal cultures after 1 day in vitro decreased cell adhesion 24 hours later and primary dendrite length 96 hours later. 150 nM sAPPα and sAPPβ induced a similar increase of axon outgrowth, although this increase was already significant at 100 nM sAPPα. …”

Model for penetratin-phospholipid membranes interactions. by Ofelia Maniti (247890)

“…<p>A) The association of penetratin with PG membranes results in the conformational change of the peptide with α-helix and β-sheet contributions and a decrease in membrane fluidity. B) With PC membranes, the peptide associates in a two step processes but remains quite unstructured and does not change notably the fluidity of the membrane. …”

Neutralization of point mutants of B.1.351 and D614G spike-pseudotyped lentiviral particles by convalescent plasmas from B.1.351 and early 2020-infected individuals. by Allison J. Greaney (11046384)

“…The fold-change IC50 is calculated relative to the geometric mean of two wildtype technical replicates performed on the same assay date. …”

Optimization of Soft Carbon Negative Electrode in Sodium-Ion Batteries Using Surface-Modified Mesophase-Pitch Carbon Fibers (Supporting Information) by Yuki FUJII (16010578)

Higher egg consumption associated with increased risk of diabetes in Chinese adults - China Health and Nutrition Survey. by Wang, Yue

“…Logistic regression was used to examine the association. The mean age of the study population was 50·9 (sd 15·1) years. …”
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Selective blockade of peripheral β₂AR restored HPV in IH-rats. by Hisashi Nagai (650547)

“…The tungsten wire in the bottom right of each image is a reference of 50 µm diameter. (B) Relationship between vessel size and the magnitude of pulmonary vasoconstriction (% decrease in vessel diameter) in response to acute hypoxia (10% O₂ for 10 min) in N-rats and IH-rats with or without β-blocker administration. …”

Effects of Gu-4 on survival and expression profiles of TNF-α and IL-10 in septic mice. by TingTing Yan (5652595)

“…Gu-4 administration significantly reduced LPS-induced mortality at the doses of 0.88, 1.06, 1.27 and 1.53 mg/kg. *: p<0.05 indicates a significant decrease in mortality by Gu-4 treatment versus saline treatment as determined by log-rank test. β-lactose or dexamethasone (Dex) did not produce significant improvement in survival. …”

Mitochondrial Ca²⁺ uptake in permeabilized H295R cells transfected with <i>OPA1</i> or <i>Mfn1</i> siRNA. by László Fülöp (203208)

“…On day 5 the cells were permeabilized, superfused with a cytosol-like medium, Ψ_m was dissipated with 10 µM rotenon, 8 µg/ml oligomycin, 10 µM FCCP and 50 ng/ml valinomycin for 2 minutes. …”

AP-1 knockdown potentiates the effect of AP-3 knockdown on regulated secretion. by Daniel W. Sirkis (463685)

“…<p>(A) PC12 cells were transfected with pooled siRNA directed against AP-1 γ or pooled nontargeting siRNA as control. …”

MMR activities in the APE and hMSH6 expressing cells by In-Youb Chang (10654)

“…The repair efficiency was calculated as the percentage of decrease in the mixed-color colonies. The values are a mean ± SD from three separate experiments. …”

The viability and morphology of IL-13- or IL-13+ cell cultures. by Andrea Stadnikova (3929546)

“…Cell viability data are presented in a vertical scatter plot graph with line indicating mean. …”

Factor of change of pO (ΔpO) segregated with respect to the initial median pO by Bernardino Clavo (3925)

“…The boxes show the 25%–75% inter-quartile interval, which includes the 50% values. The horizontal lines in the boxes represent the median and the * represents the mean of ΔpO for both groups of tumors at each measurement time-point. …”

The activity of TRPV1 is dependent on phosphoinositides. by Hae-Jin Kweon (525019)

“…Data are mean ± SEM.</p>…”

Cartilage and subchondral bone degeneration scores at 7 and 12 wks after the start of the experiment. by Junya Sakamoto (4286575)

“…<p><b>A:</b> a, b and c; Representative toluidine blue staining of each group at 7 wks after the start of experiment. …”

Dataset for penetration resistance, aggregate stabiltiy and infiltration of biocrusts of the Caatinga, NE Brazil by Michelle Szyja (14124273)

“…., 2023: Biological soil crusts decrease infiltration but increase erosion resistance in a human-disturbed tropical dry forest. …”

Significant Reductions in Mortality in Hospitalized Patients with Systemic Lupus Erythematosus in Washington State from 2003 to 2011 by Louisa B Goss (757328)

“…The mean age of the group was 51.5 years (95% CI: 50.6-52.3) in 2003 and 51.3 years (95% CI: 50.6-52.0) in 2011. …”

Changes of the normalized volume V/V₀ in glioblastoma cell lines in response to sucrose- and inositol-substituted solutions of different osmolalities (LHS and RHS column... by Simon Memmel (518138)

“…Each data point represents the mean ± SE of 50–120 individual cells. Continuous curves in <i>A</i> show best least-square fits of the Lúcio-model <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0087052#pone.0087052-Lcio1" target="_blank">[50]</a> to the data. …”