DELTA-1/NOTCH signaling in the caudal spinal cord of chick embryos. by Barbara Hämmerle (36261)

“…<p>A–A′. Confocal projection over 50 µm from a dorsal aspect of the prospective spinal cord at the level of the 12^th and 13^th somites counted from rostral of a HH13 chick embryo that was electroporated with NICD at stage HH10 when that region was part of the PNTZ. …”

EARS lake activity is predicted by regional paleoclimate records. by Susanne Shultz (471583)

“…Best fit model was identified using the stepAIC function in R package Mass <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0076750#pone.0076750-Venables1" target="_blank">[38]</a>. …”

Short-term time-restricted feeding during the resting phase is sufficient to induce leptin resistance that contributes to development of obesity and metabolic disorders in mice by Katsutaka Oishi (278169)

Reduced thermal hypersensitivity in S1P₁^−/−mice. by Norbert Mair (113808)

Supporting information data. by Miriam Serrano Soliva (19485617)

Dependency of Cl⁻ accumulation on the site of synaptic input and KCC2 level. by Nicolas Doyon (344567)

“…Synaptic background activity was the same as in <b>B</b>. Mean IPSC was measured at a “test” synapse activated at 40 Hz for 200 ms every second over 50 s of simulated time. …”

Knockdown of <i>CPSF6</i> leads to global shifts in PAS usage as well as major transcript and protein abundance changes. by Christoph Schmal (395936)

“…(<b>G</b>) Representative examples that show a decrease (<i>SHISA2</i>, top) or increase (<i>HIPK1</i>, bottom) of transcript abundance upon <i>CPSF6</i> knockdown. …”

Microtubule inhibitors cause cell cycle arrest and induce RKIP expression. by Saad Yousuf (541082)

“…Analysis for apoptosis was performed using a FACSCalibur flow cytometer (Data represents the mean ± S.D., of 2 independent experiments performed in duplicate). …”

Nef Targets ABCA1-Dependent Cholesterol Efflux by Zahedi Mujawar (379543)

<i>S</i>. <i>pneumoniae</i> RNA regulators are ligand responsive and most designed mutations function as anticipated. by Indu Warrier (581139)

“…Bar height indicates the mean replicate value, error bars indicate standard error of the mean, individual points shown in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011188#pgen.1011188.s009" target="_blank">S2 Fig</a>. …”

The sterile insect technique for the management of the spotted wing drosophila, <i>Drosophila suzukii</i>: Establishing the optimum irradiation dose by Geneviève Lanouette (4476472)

“…Females irradiated with a dose of 50 Gy or more had almost no fecundity. …”

Ca2+-dependent release of ATP can be evoked in the cortical astrocytes of the wild-type but not of the dn-SNARE mice. by The PLOS Biology Staff (614265)

“…(C) Elevation of the Ca2+ level in any of the dn-SNARE astrocytes did not lead to activation of phasic purinergic currents in the sniffer cell. Inlays in (A–C) show examples of individual phasic currents recorded at moments indicated; scale bars are 50 ms and 10 pA. …”

Representative results of integrate-and-fire simulations for different learning rules. by Kendra S. Burbank (180062)

“…The simulations in <b>b–d</b> were classified as having “extreme weights” meaning that >50% of the weights were either at 0 or at the weight boundaries (±50). …”

Organ level model. by Shayoni Ray (179927)

“…<p>An organ-level simulation containing three ideally localized clefts is shown at (a) 0 MCS and (b) 1500 MCS (Scale = 50 µm). The results were quantified with (c) cleft depth and (d) spanning angle. …”

Cerebellar cortex of SCA3 patients. by Tzu-Yun Wang (427574)

Cerebral cortex of SCA3 patients. by Tzu-Yun Wang (427574)

Untargeted <i>In Vitro</i> Metabolomics data from <i>Burkholderia cenocepacia </i>J2315, H111 and <i>Staphylococcus aureus </i>NRS77 Biofilm Supernatant by Hayden Skaggs (20833868)

“…Thresholds were set as spectral similarity ≥ 0.4, retention time difference ≤ 0.15 and m/z variation window ≤ 5 ppm. 2D LC-MS/MS data without a match with the metabolites in the proprietary database were further analyzed using Compound Discoverer software (v 2.0, Thermo Fisher Scientific, Germany), where MS/MS spectra similarity score threshold was set ≥ 40 with a maximum score of 100. …”

Image_3_The Streptomyces coelicolor Small ORF trpM Stimulates Growth and Morphological Development and Exerts Opposite Effects on Actinorhodin and Calcium-Dependent Antibiotic Prod... by Alberto Vassallo (8466042)

Image_1_The Streptomyces coelicolor Small ORF trpM Stimulates Growth and Morphological Development and Exerts Opposite Effects on Actinorhodin and Calcium-Dependent Antibiotic Prod... by Alberto Vassallo (8466042)

Image_4_The Streptomyces coelicolor Small ORF trpM Stimulates Growth and Morphological Development and Exerts Opposite Effects on Actinorhodin and Calcium-Dependent Antibiotic Prod... by Alberto Vassallo (8466042)