Data_Sheet_1_Antibacterial activity and mechanism of Stevia extract against antibiotic-resistant Escherichia coli by interfering with the permeability of the cell wall and the memb... by Xu Chen (432759)

Table_2_Odorant-Binding Proteins Contribute to the Defense of the Red Flour Beetle, Tribolium castaneum, Against Essential Oil of Artemisia vulgaris.docx by Yuan-chen Zhang (9321452)

Conceptual summary of GRS effects across studies. by Marco K. Wittmann (14710470)

Combinatorial Synthesis and in Vitro Evaluation of a Biaryl Hydroxyketone Library as Antivirulence Agents against MRSA by Guanping Yu (1345770)

“…An acylation bond-forming process afforded resorcinols (<b>1</b>) and aryloxy acetonitriles (<b>2</b>) as synthons. A Lewis-acid-activated Friedel–Crafts’ acylation step involving a nitrile functionality of <b>2</b> by ZnCl₂, followed by nucleophilic attack by <b>1</b> was executed to obtain biaryl hydroxyketones in excellent yields. …”

Combinatorial Synthesis and in Vitro Evaluation of a Biaryl Hydroxyketone Library as Antivirulence Agents against MRSA by Guanping Yu (1345770)

“…An acylation bond-forming process afforded resorcinols (<b>1</b>) and aryloxy acetonitriles (<b>2</b>) as synthons. A Lewis-acid-activated Friedel–Crafts’ acylation step involving a nitrile functionality of <b>2</b> by ZnCl₂, followed by nucleophilic attack by <b>1</b> was executed to obtain biaryl hydroxyketones in excellent yields. …”

Assessment of sesquiterpene lactones isolated from <i>Mikania</i> plants species for their potential efficacy against <i>Trypanosoma cruzi</i> and <i>Leishmania</i> sp. by Laura C. Laurella (469416)

“…<div><p>Four sesquiterpene lactones, mikanolide, deoxymikanolide, dihydromikanolide and scandenolide, were isolated by a bioassay-guided fractionation of <i>Mikania variifolia</i> and <i>Mikania micrantha</i> dichloromethane extracts. …”

C-I TF screen quantitative phenotypic analyses. by Eswar Prasad R. Iyer (177455)

“…The direction of arrow represents increase (up), decrease (down) or no change (hyphen). Size bar corresponds to 50 microns.…”

Quantitative comparison of protein expression between two <i>P</i>. <i>vivax</i> salivary gland sporozoite field isolates. by Kristian E. Swearingen (2301094)

“…The population of log-transformed protein ratios of proteins detected in both samples assumed a Gaussian distribution with a mean near zero. …”

Characterization of gemcitabine-resistant subclones. by Fredrik I. Thege (12646919)

“…E-cadherin enrichment at cell-cell junctions was determined by calculating the ratio of the mean E-cadherin intensity proximal to the cellular edge and the mean E-cadherin intensity in the rest of the cell using CellProfiler, see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0267882#pone.0267882.s002" target="_blank">S2 Fig</a> for analysis pipeline. …”

Shapley Additive Explanations (SHAP) summary plot. by Yue Lv (549862)

Deconvolution of Kombucha Tea facilitates the creation of fermenting and non-fermenting mixes of KTM. by Rachel N. DuMez-Kornegay (18271479)

“…(C) Oil Red O staining of day 1 adult animals fed an <i>E</i>. <i>coli</i> OP50, KTM-Mix, or KTMs diet, as well as a 5X concentrated version of the KTM diet (mean ± SD, ****, <i>P</i><0.0001, one-way ANOVA). …”

Anti-Neoplastic Effects of Annonacin against Renal Cell Carcinoma by Munusamy, Shankar

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DataSheet1_Danggui-Shaoyao-San Improves Gut Microbia Dysbiosis and Hepatic Lipid Homeostasis in Fructose-Fed Rats.docx by Jing Yin (143422)

“…The results showed that the 50% methanol extract (HME) was more effective. It was worth noting that hydroxysteroid 17β-dehydrogenase 13 (HSD17β13) as a critical element of increasing blood lipid biomarker-triglyceride (TG), was decreased markedly by DSS. …”

Adverse effect of ND251 aggregates on neurite outgrowth. by Huei-Ying Li (210957)

“…Cells expressing ND251S5A had a further decrease in the percentage of neurite-bearing cells in comparison with ND251. …”

Efficacy of dexamethasone and ACTH in drug resistant pediatric epilepsy. by Nicola Marchi (4967)

“…(<b>B</b>) Mosaic plot showing the correlation between etiology of epilepsy and likelihood of a response ≥50%. Note that etiology did not always predict response. …”

Image_6_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_4_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_1_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_5_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_2_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”