Table2_Optimizing tacrolimus dosing in Hispanic renal transplant patients: insights from real-world data.DOCX by Athanasios Chamzas (19699780)

“…The estimated apparent clearance was 13.7 L/h for a typical patient weighing 70 kg and at 30% hematocrit, demonstrating a 40% decrease in clearance compared to other patient populations. …”

Table1_Optimizing tacrolimus dosing in Hispanic renal transplant patients: insights from real-world data.DOCX by Athanasios Chamzas (19699780)

“…The estimated apparent clearance was 13.7 L/h for a typical patient weighing 70 kg and at 30% hematocrit, demonstrating a 40% decrease in clearance compared to other patient populations. …”

Data_Sheet_1_Antiproliferative effect of boldine on neural progenitor cells and on glioblastoma cells.PDF by Enrique Jiménez-Madrona (16836648)

“…Analysis of the effect of boldine (25–600 μM) on different types of primary human GBM cells (GBM59, GBM96, and U87-MG) showed a concentration-dependent decrease in GBM cell growth. …”

Image1.TIF by Bruna S. de Alencar Silva (5002919)

“…Regarding the chronic effects, it was observed a decrease of all cytokines, except IL-10 (p < 0.05). …”

Image2_Optimizing tacrolimus dosing in Hispanic renal transplant patients: insights from real-world data.JPEG by Athanasios Chamzas (19699780)

“…The estimated apparent clearance was 13.7 L/h for a typical patient weighing 70 kg and at 30% hematocrit, demonstrating a 40% decrease in clearance compared to other patient populations. …”

TF-specific motif turnover drives TF binding divergence. by Mathilde Paris (17385)

Hair cell number and vestibular function recovers after hair cell ablation. by Tian Wang (115287)

“…B-F) After DT treatment, both the hair cell number and area of sensory epithelium decreased at P15, followed by a partial recovery at P30 and P60. …”

Ca2+-dependent release of ATP can be evoked in the cortical astrocytes of the wild-type but not of the dn-SNARE mice. by The PLOS Biology Staff (614265)

“…(C) Elevation of the Ca2+ level in any of the dn-SNARE astrocytes did not lead to activation of phasic purinergic currents in the sniffer cell. Inlays in (A–C) show examples of individual phasic currents recorded at moments indicated; scale bars are 50 ms and 10 pA. …”

Altered Astrocytic Swelling in the Cortex of α-Syntrophin-Negative GFAP/EGFP Mice by Miroslava Anderova (155561)

“…Similarly, evaluation of relative α changes showed a significantly smaller decrease in α-syntrophin knockout mice only during severe pathological conditions, but not during mild stimuli. …”

Data_Sheet_1_Long-Term Prognosis of Cognitive Function in Patients With Idiopathic Normal Pressure Hydrocephalus After Shunt Surgery.xlsx by Akihiro Kambara (10006775)

“…The patients were classified in to the cognitive decline group [11 (23%) patients; a decrease in the MMSE score by ≥ 2 points 2 years after surgery] and the maintenance/improvement group [37 (77%) patients]. …”

Table1_Baseline Plasma Metabotype Correlates With Direct-Acting Antiviral Therapy Nonresponse for HCV in HIV–HCV Coinfected Patients.XLSX by Gaurav Tripathi (3163251)

“…Post therapy, 62 plasma metabolites (12 upregulated and 50 downregulated, FC±1.5, p < 0.05) differentiated nonresponders from responders and highlighted a significant increase in the steroid and histidine metabolism and significant decrease in tryptophan metabolism and ascorbate and pyruvate metabolism in the nonresponders. …”

Partial silencing of GFP requires both EhRNaseIII and ScaAgo1. by Justine M. Pompey (268775)

“…FACS histogram of GFP fluorescence in the indicated strains show a decrease in GFP fluorescence in strain expressing EhRNaseIII using the strong GFP silencing hairpin but only in the strain expressing ScaAgo1. …”

datasheet1_In Vitro, In Vivo and In Silico Effectiveness of LASSBio-1386, an N-Acyl Hydrazone Derivative Phosphodiesterase-4 Inhibitor, Against Leishmania amazonensis.docx by Dahara Keyse Carvalho Silva (9774635)

“…In vitro incubation with LASSBio-1386 reduced the percentage of Leishmania-infected macrophages and the number of intracellular parasites (EC₅₀ = 9.42 ± 0.64 µM). Also, in vivo treatment of BALB/c mice infected with L. amazonensis resulted in a decrease of lesion size, parasitic load and caused histopathological alterations, when compared to vehicle-treated control. …”

MK-2206 induced cytotoxicity, inhibited proliferation and was able to overcome the protective effects of the tumor microenvironment. by Vijay Ramakrishnan (117159)

“…<p>When we cultured MM cell lines with indicated concentrations of MK-2206 for 48 hrs we observed dose dependent decrease in <b>A)</b> viability as observed by MTT assays and <b>B)</b> tritiated thymidine uptake indicative of inhibition of proliferation albeit with differences in the sensitivity of cell lines to MK-2206. …”

Datasheet1_Hyperbaric effects on heart rate in professional SCUBA divers in thermal water.pdf by Luigi Fattorini (19758798)

Retinal histology examination after 10 weeks of ocular hypertension. by Nicolás Belforte (328093)

“…Scale bar: Upper panel  =  50 µm; Middle panel  =  50 µm. Data are the mean ± SEM (n = 5 animals per group). * p<0.05, ** p<0.01 vehicle injected eyes without ischemia pulses (sham), a: p<0.05, b: p<0.01 versus CS-injected eyes without ischemia pulses (sham), by Tukey's test. …”

Non-Temperature Induced Effects of Magnetized Iron Oxide Nanoparticles in Alternating Magnetic Field in Cancer Cells by Sudath Hapuarachchige (2203699)

Allelopathic Effects of Different Plant Water Extracts on Yield and Weeds of Wheat by M. NAEEM (5862101)

“…In this study, mixtures of allelopathic water extracts of sorghum + sunflower and sorghum + sunflower + mulberry were sprayed each at 12, 15, 18 and 21 L ha-1 at 40 and 55 days after sowing in wheat to control wild oats (Avena fatua), little seed canary grass (Phalaris minor), lamb’s quarters (Chenopodium album) and swine cress (Coronopus didymus). A synthetic herbicide Affinity 50 WP (Carfentrazone-ethyl 0.75% + Isoproturon 50% applied at 1000 g a.i., ha-1) and a weedy check were kept as a control treatment. …”

Self-Powered Biosensing System with Multivariate Signal Amplification for Real-Time Amplified Detection of PDGF-BB by Futing Wang (14851840)

Specificities mediating neutralization breadth and potency in the top 42 Protocol C neutralizers. by Elise Landais (845745)

“…Absent (-), very weak (+/-), weak (+), moderate (++), strong (+++), phenotype was attributed based on i) the median fold or average percent decrease in ID50 and ii) the fraction of viruses which neutralization ID50 was decreased <2 fold, <10 <50 fold or <20%, <40%, <60%, <80%. …”