Two-step regulation time course dynamics varying the period of . by Luca Cerone (186603)

“…<p>The plots show the expression of a gene (blue) controlled by the symmetric signal (black) for the two-step model. The left (right) column shows the case in which the value of (green dashed line) is above (below) the average value at stationary regime of the transcription factor (red curve). …”

Discovery of Novel Substituted <i>N</i>‑(4-Amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide Analogues as Potent Human Adenovirus Inhibitors by Jimin Xu (2208961)

“…An effective therapy for human adenovirus (HAdV) infections in immunocompromised patients and healthy individuals with community-acquired pneumonia remains an unmet medical need. We herein reported a series of novel substituted <i>N</i>-(4-amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide analogues as potent HAdV inhibitors. …”

The expression of 5-hmC was decreased in ESCC tissues and cell lines. by Xuejiao Shi (1684186)

Cellular uptake of [¹⁴C]docosahexaenoic acid (DHA) by RBECs transfected with MFSD2A siRNA. by Takuro Iwao (14636741)

CK8 knockdown and ROCK1 inhibitor suppressed rTsSPc-induced disruption of the Caco-2 monolayer and blocked rTsSPc-promoted IIL invasion. by Wen Wen Zheng (17721404)

Subjects:

The injectable contraceptives depot medroxyprogesterone acetate and norethisterone enanthate substantially and differentially decrease testosterone and sex hormone binding globulin... by Chanel Avenant (409756)

“…Both contraceptives substantially decreased, from D0 to 25W, the total testosterone [DMPA-IM D0 0.560, 25W 0.423 nmol/L, -24.3% (p < 0.0001); NET-EN D0 0.551, 25W 0.253 nmol/L, -54.1%, (p < 0.0001)], SHBG [DMPA-IM D0 45.0, 25W 32.7 nmol/L, -29.8% (p < 0.0001); NET-EN D0 50.2, 25W 17.6 nmol/L, -65.1% (p < 0.0001)], and calculated free testosterone levels [DMPA-IM D0 6.87, 25W 5.38 pmol/L, -17.2% (p = 0.0371); NET-EN D0 6.00, 25W 3.70, -40.0% (p < 0.0001)]. …”

Exercise capacity at baseline, pre-lockdown, and post lock down measurements (n = 198). by Feras Haskiah (14204097)

Host population bottlenecks decrease microbiome diversity. by Michael Ørsted (5926028)

Pathogen loads on carbohydrate-poor and carbohydrate-rich diets. by Adam Bajgar (730380)

DHA does not affect the expression of IFNγR1 & R2 but decreases STAT1 phosphorylation in non-infected J774A.1 cells primed with IFNγ. by Diana L. Bonilla (248104)

BIC of models tested throughout model building. by Guillaume Lingas (9955528)

Linear decrease of delta power (1.1–5.0 Hz) across the first three sleep cycles in the cortical, hippocampal and scalp recordings. by Fabio Moroni (34208)

Blood soluble factors related to wound healing vary with the age. by María Paz Saldías (4430032)

Self-reported change in diet, physical activity and medication taking compared to pre-COVID-19 in relation to trajectories of HbA1c in people with diabetes (N = 4,925). by Martin Gillies Banke Rasmussen (10227291)

Characterization of Niphatenones that Inhibit Androgen Receptor N-Terminal Domain by Carmen A. Banuelos (636867)

“…Both enantiomers had similar IC50 values of 6 µM for inhibiting the full-length AR in a functional transcriptional assay. …”

The relative difference between the target dose of plan S₅₀ and base plan (n by Huaqu Zeng (20601563)

“…</b> Among the 21 patients in plan S₅₀, only one showed a decrease in target dose exceeding 2% but remaining below 2.5% compared to the base plan. …”

Old rats present impaired wound healing compared to young rats. by María Paz Saldías (4430032)

(A) Shape of the osteotomies during the 3-step MIPS drilling procedure. by Marsel Ganeyev (21453399)

Purpose of deinfibulation, (N = 73). by Wafa Y. Ahmed (20727327)

Vesicle <i>p</i>H fluctuations are constant over a range of <i>p</i>H values. by Apeksha Singh (8174256)