SS- and AGEs-induced simultaneous increases in proliferation and apoptosis of VSMCs are closely associated with selective activation of three members the MAPK subfamily. by Suning Ping (172755)

“…<b>(A, E, I, M)</b> Either SS or AGEs could induce simultaneous increases in proliferation (Ki-67 positive, red, arrows) and apoptosis (TUNEL positive, green, arrowheads), and combined stimulation with both had a synergistic effect. …”

VER-155008 abrogated viral protein synthesis pre-translationally in TREx BCBL1-RTA cells. by Belinda Baquero-Pérez (706834)

“…(C) Immunoblot analysis showing that reactivated cells treated with non-cytotoxic inhibitor concentrations (1 to 2.5 μM) for 24 h revealed a decrease in viral proteins compared with DMSO-treated samples while cellular proteins remained unaffected. …”

Lagged biodiversity recoveries. by Roberto Latorre (282007)

“…Notably, the figure illustrates cases where biodiversity loss is driven by reduced speciation rather than increased extinction (e.g., the event indicated by the arrow, where a prior burst of speciation reaching nearly 50% is followed by a sharp drop in speciation, while extinction rates remain nearly constant or even decrease). …”

Physiological and transcriptomic data for <i>sdc</i>, <i>dc</i> and <i>sdc/dc</i> mutants. by Diego H. Sanchez (230286)

“…Right: Relative mean aerial biomass as percentage of controls obtained from the data shown on the left, denoting a decrease of at least 30% in relative biomass after treatment of genetic backgrounds harboring the <i>sdc</i> mutation. …”

Spatial-temporal variation in litterfall in seasonally dry tropical forests in Northeastern Brazil by V. F. P. Araújo (7141901)

“…The inter- and intra-annual variation in litterfall production was positively correlated with precipitation and evapotranspiration rates, and four months after the highest precipitation rates, there was a marked decrease in litterfall occurred during the dry season. …”

Expression of MP does not interfere with the silencing pathway. by Hannes Vogler (272256)

“…In the presence of MP, the GFP siRNA levels are reduced by about 50% compared to the empty vector control, whereas dMP causes a slight increase. …”

DataSheet_2_Unveiling drug-tolerant and persister-like cells in Leishmania braziliensis lines derived from patients with cutaneous leishmaniasis.xlsx by Marlene Jara (774474)

“…</p>Results and discussion<p>We demonstrated in vitro that a variable proportion of cells remained viable, showing all the criteria of DT and not of DR: i) signatures of quiescence, under drug pressure: reduced proliferation and significant decrease of rDNA transcription; ii) reversibility of the phenotype: return to low IC₅₀ after removal of drug pressure; and iii) absence of significant genetic differences between exposed and unexposed lineages of each strain and absence of reported markers of DR. …”

Table 1_Preliminary clinical activity of TP-0903 in relapsed or refractory acute myeloid leukemia with FLT3-ITD mutations.docx by Bhavana Bhatnagar (11016429)

“…Three heavily treated relapsed/refractory AML patients with FLT3-ITD were treated with TP-0903 50 mg daily, on a phase 1b/2 clinical trial, for as long as disease response or clinical benefit was observed. …”

Effect of rotenone on the striatum, VTA, and SNc TH immunoreactivity. by Nian Xiong (218611)

“…The TH immunoreactivity on the ipsilateral side of the striatum was decreased by 66.4% (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007878#pone-0007878-g004" target="_blank">Figure 4I–J</a>; *P<0.05, as compared to the contralateral side). …”

Image_1_Habenular Involvement in Response to Subcallosal Cingulate Deep Brain Stimulation for Depression.TIF by Gavin J. B. Elias (12044813)

“…Clinical response to treatment (≥50% decrease in HAMD-17 from baseline to 12 months post-operation) was significantly associated with longitudinal Hb volume change: responders tended to have increased Hb volume over time, while non-responders showed decreased Hb volume (t = 2.4, p = 0.021). …”

Data_Sheet_1_Cu5FeS4 Nanoparticles With Tunable Plasmon Resonances for Efficient Photothermal Therapy of Cancers.docx by Lei Yuan (713591)

“…After surface modification with polyethylene glycol (PEG), the CFS nanoparticles with a plasmon resonance absorption peak at 764 nm can serve as promising photothermal agents, showing good biocompatibility and excellent photothermal performance with a photothermal conversion efficiency of up to 50.5%, and are thus used for photothermal therapy of cancers under the irradiation of an 808-nm laser. …”

Oligocene-Miocene middle crustal flow in southern Tibet: geochronology of Mabja Dome by J. Lee (2845193)

“…Zircons and monazite from a post-tectonic two-mica granite yield ages of 14.2 ± 0.2 Ma and 14.5 ± 0.1, respectively, indicating that vertical thinning and subhorizontal stretching had ceased by the middle Miocene. …”

Population dynamics. by Joshua Tasoff (776736)

“…When <i>u</i>¹ < <i>u</i>² the population ratio increases, and when <i>u</i>² < <i>u</i>¹ the population ratio decreases. …”

Antibodies of the PGT121 family compete with sCD4, but not PGV04, for binding to gp120 in solution and on the cell-surface. by Jean-Philippe Julien (135641)

Fitness of the ligases and their relationships in crude evolutionary time. by Carolina Díaz Arenas (504034)

“…Populations where poly-A mutants (<i>e.g</i>., A27) are present in high frequency decrease in size, and are at risk of extinction, due to the low mean fitness value of the population, which keeps decreasing as adenylation tracks are extended. …”

CTR-C PDZ- binding motif mutation and TJ disruption and invasion. by Ahmed Aljameeli (2548528)

“…<p>A. Transepithelial Electric Resistance (TER): Polarized PC-3v, PC-3-CTRwt and PC-3CTR-∆ESS cells were serum-starved for 4 hours, then treated with/without 50 nM CT. …”

Exercise-Induced Splanchnic Hypoperfusion Results in Gut Dysfunction in Healthy Men by Kim van Wijck (212826)

“…Splanchnic perfusion rapidly decreased during exercise, reflected by increased gap_g-apCO₂ from −0.85±0.15 to 0.85±0.42 kPa (p<0.001). …”

Data_Sheet_1_The Association Between Shift Work and Immunological Biomarkers in Nurses.PDF by Bjørn Bjorvatn (35254)

“…In contrast, MCP-1 levels were lower (large effect size) both after a day shift (22% decrease) and a night shift (12% decrease) compared with after a night of sleep.…”

Validation of E. coli Signaling Network Model by Burton W Andrews (274358)

“…<div><p>(A) Response of the E. coli signaling network model is plotted for a 0.1-mM step increase in chemoattractant concentration from 0.2 mM at 10 s. …”

Nef Targets ABCA1-Dependent Cholesterol Efflux by Zahedi Mujawar (379543)