Systemic effects in naïve mice injected with immunomodulatory lectin ArtinM by Patrícia Kellen Martins Oliveira Brito (4543702)

“…IL-12, IFN-γ, TNF-α, and IL-10 measurements in the liver, kidney, spleen, heart, and lung homogenates revealed decreased IL-10 level in the heart and lung of mice injected with 5.0 μg ArtinM. …”

Datasheet1_TRIM8 as a predictor for prognosis in childhood acute lymphoblastic leukemia based on a signature of neutrophil extracellular traps.docx by Waihin Tin (19440019)

“…Correlation analysis revealed significant associations with B cells, NK cells, mast cells, T cells, plasma cells, dendritic cells, and monocytes. The IC₅₀ values of drugs such as all-trans-retinoic acid (ATRA), axitinib, doxorubicin, methotrexate, sorafenib, and vinblastine were increased, while dasatinib exhibited a lower IC₅₀. …”

Table1_TRIM8 as a predictor for prognosis in childhood acute lymphoblastic leukemia based on a signature of neutrophil extracellular traps.xlsx by Waihin Tin (19440019)

“…Correlation analysis revealed significant associations with B cells, NK cells, mast cells, T cells, plasma cells, dendritic cells, and monocytes. The IC₅₀ values of drugs such as all-trans-retinoic acid (ATRA), axitinib, doxorubicin, methotrexate, sorafenib, and vinblastine were increased, while dasatinib exhibited a lower IC₅₀. …”

Table2_TRIM8 as a predictor for prognosis in childhood acute lymphoblastic leukemia based on a signature of neutrophil extracellular traps.docx by Waihin Tin (19440019)

“…Correlation analysis revealed significant associations with B cells, NK cells, mast cells, T cells, plasma cells, dendritic cells, and monocytes. The IC₅₀ values of drugs such as all-trans-retinoic acid (ATRA), axitinib, doxorubicin, methotrexate, sorafenib, and vinblastine were increased, while dasatinib exhibited a lower IC₅₀. …”

A model for PFK2 in maintaining PPi homeostasis and balanced catabolism and anabolism in <i>Toxoplasma</i>. by Xuke Yang (10910791)

“…<p>The biosynthesis of macromolecules such as proteins, DNA and RNA generates PPi, which is then converted to Pi by PPase and the PPi-dependent phosphofructokinase PFK2. The hydrolysis of PPi by PFK2 is coupled to the phosphorylation of F6P to FBP, the committed step of glycolysis. …”

R″→T transition for a single subunit of GroEL. by Zheng Yang (264955)

“…The end states refer to subunit A in the PDB structures 1GRU and 1GR5. Results are shown for <i>F_min</i> = 0.4, 0.5, 0.6 and 0.7, corresponding to the allowable angular deviations of up to 50.8°, 45.0°, 39.2° and 33.2°, respectively, between and <i>v</i><i>_A</i>^(<i>k</i>) (or <i>v</i><i>_B</i>^(<i>k</i>)). …”

Data_Sheet_2_The cognitive adaptability and resiliency employment screener (CARES): tool development and testing.PDF by Wilfredo Manuel R. Torralba (17064519)

“…Introduction<p>To decrease psychological risk for content moderators, the study initiated the first steps of developing a robust employment screening tool, namely, the Cognitive Adaptability and Resiliency Employment Screener.…”

Image_2_Oxidized LDL Causes Endothelial Apoptosis by Inhibiting Mitochondrial Fusion and Mitochondria Autophagy.jpeg by Jia Zheng (140297)

“…Opa1 overexpression reversed this effect by increasing endothelial cell viability and decreasing apoptosis. Interestingly, inhibition of mitophagy or mitochondrial fusion through transfection of siRNAs against Atg5 or Mfn2, respectively, abolished the protective effects of Opa1. …”

Image_2_Oxidized LDL Causes Endothelial Apoptosis by Inhibiting Mitochondrial Fusion and Mitochondria Autophagy.jpeg by Jia Zheng (140297)

“…Opa1 overexpression reversed this effect by increasing endothelial cell viability and decreasing apoptosis. Interestingly, inhibition of mitophagy or mitochondrial fusion through transfection of siRNAs against Atg5 or Mfn2, respectively, abolished the protective effects of Opa1. …”

Environmental effects on the predictability of the phenotype and the portability of a PGS. by Pablo Yubero (16389864)

“…Dots and lines correspond to individual means and a running average (<i>n</i> = 50), respectively.…”

Supplementary Material for: The Association of Proteinuria Target Achievement Timing and Stability with Adverse Kidney Outcomes Among Patients with IgA Nephropathy: A Cohort Study by figshare admin karger (2628495)

“…We analyzed the association between those three metrics and the composite kidney outcome, which was defined as the first occurrence of either end-stage kidney disease (ESKD or a >50% decrease in eGFR from baseline. Results: In Part A, the primary outcome occurred in 166 (18.65%) patients. …”

Splicing assays of wt and mutant pre-mRNA in the absence and presence of wild-type StpA and mutant G126V-StpA by Rupert Grossberger (9105)

“…The reactions were performed in the presence of 5 mM MgCl, 0.5 mM GTP, 50 mM Tris–HCl (pH 7.3) and 0.4 mM spermidine (see Materials and Methods). () Splicing of the wt intron pre-RNA without added protein (full circles), with the addition of 1.4 μM wild-type StpA (full squares) or 1.4 μM G126V-StpA mutant (empty squares). () Splicing of the C865U pre-RNA intron mutant without protein (full circles), with addition of 1.4 μM wild-type StpA (full squares) or 1.4 μM G126V-StpA mutant (empty squares). …”

Stability of Afsup. by Gabriele Sass (335744)

Temperature: A major climatic determinant of cowpea production by Juliane Rafaele Alves Barros (10398785)

“…Thus, the objective of this study was to evaluate the influence of water availability and temperature on the performance of cowpea cultivars. A greenhouse experiment was conducted using a 4 × 2 × 5 factorial arrangement, with four replications. …”

Syntheses, Characterization, and Photophysical Properties of Conjugated Organometallic Pt-Acetylide/Zn(II) Porphyrin-Containing Oligomers by Feng-Lei Jiang (1449181)

“…Two conjugated organometallic oligomers of the type (−CCPt(L)₂CC(Zn<b>P</b>)−)_<i>n</i> and model compounds [PhCCPt(L)₂CC(Zn<b>P</b>)CCPt(L)₂CCPh] with L = tri(<i>n</i>-butyl)-phosphine and Zn<b>P</b> = zinc(II)(10,20-bis(Ar)porphyrine) (Ar = mesityl (Mes; <b>P1</b> and <b>M1</b>) or 3,4,5-trihexadecyloxyphenyl (<b>P2</b> and <b>M2</b>)) were synthesized and characterized (¹H and ³¹P NMR, HRMS, elemental analysis, IR, GPC, and TGA). …”

A regulatory gene network of foam-cell formation. by Josefin Skogsberg (88384)

“…CE accumulation (given as average percentage next to each node) was decreased (blue) by siRNA inhibition of 5 genes and increased (red) by inhibition of 2 genes; inhibition of 1 gene had no effect (black) (see also <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000036#pgen-1000036-t003" target="_blank">Table 3</a>). …”

Esculetin, a coumarin derivative, exerts in vitro and in vivo antiproliferative activity against hepatocellular carcinoma by initiating a mitochondrial-dependent apoptosis pathway by J. Wang (472325)

“…Esculetin significantly inhibited proliferation of HCC cells in a concentration- and time-dependent manner and with an IC50 value of 2.24 mM. …”

Water immersion and one-year storage influence the germination of the pyrenes of Copernicia alba Morong, a palm tree from a neotropical wetland by Vanessa Couto Soares (14189614)

“…<div><p>ABSTRACT Palm seeds are known for displaying dormancy and a thick endocarp that delays germination and embryo growth, but water treatments may accelerate their germination process. …”

Image_2_Memory discrimination is promoted by the expression of the transcription repressor WT1 in the dentate gyrus.tif by Leonardo Munari (17050842)

Table_1_Endometrial proteomic profile of patients with repeated implantation failure.docx by Jing Yang (13969)

“…Introduction<p>Successful embryo implantation, is the initiating step of pregnancy, relies on not only the high quality of the embryo but also the synergistic development of a healthy endometrium. …”