The association of diabetic retinopathy with metabolic syndrome. by Lu Gao (44114)

“…When patients were grouped according to the number of detected components of the metabolic syndrome, the percentage of patients with DR increased linearly with the increasing number of components in their respective groups (14.3%, 38.9%, 49.1%, 61.4%, 83.3%, respectively), whereas, the percentage of patients without DR decreased with the increasing number of components (85.7%, 61.1%, 50.9%, 38.6%, 16.7%, respectively) (Pearson χ² = 9.938, P = 0.037). …”

Fig 2 - by Leila Vahdatiraad (17382718)

Replacement of the N-type <i>Arsenophonus</i> in <i>N</i>. <i>lugens</i> with S-type <i>Arsenophonus</i> impacts the host’s insecticide resistance. by Rui Pang (1601419)

Morphometric analysis of nuclei and peroxisomes. by Claudia Colasante (101665)

Bar graphs showing the total loss rates and 95% confidence intervals for each region in Ethiopia, Kenya, and Benin. by Beatrice T. Nganso (4114768)

Multinomial logistic regression analyses predicting impact on vaccination intention by demographics (more likely vs. less likely to get vaccinated comparison). by Rikki H. Sargent (12441964)

Structure–Activity Studies of 1<i>H</i>‑Imidazo[4,5‑<i>c</i>]quinolin-4-amine Derivatives as A₃ Adenosine Receptor Positive Allosteric Modulators by Lucas B. Fallot (14106171)

“…Although having low Caco-2 permeability and high plasma protein binding, hydrophobic 2-cyclohept-4-enyl-<i>N</i>-3,4-dichlorophenyl, MRS7788 <b>18</b>, and 2-heptan-4-yl-<i>N</i>-4-iodophenyl, MRS8054 <b>39</b>, derivatives were orally bioavailable in rat. 2-Heptan-4-yl-<i>N</i>-3,4-dichlorophenyl <b>14</b> and 2-cyclononyl-<i>N</i>-3,4-dichlorophenyl <b>20</b> derivatives and <b>39</b> greatly enhanced Cl-IB-MECA-stimulated [³⁵S]GTPγS binding <i>E</i>_max, with only <b>12b</b> trending toward decreasing the agonist EC₅₀. A feasible route for radio-iodination at the <i>p-</i>position of a 4-phenylamino substituent suggests a potential radioligand for allosteric site binding. …”

Structure–Activity Studies of 1<i>H</i>‑Imidazo[4,5‑<i>c</i>]quinolin-4-amine Derivatives as A₃ Adenosine Receptor Positive Allosteric Modulators by Lucas B. Fallot (14106171)

“…Although having low Caco-2 permeability and high plasma protein binding, hydrophobic 2-cyclohept-4-enyl-<i>N</i>-3,4-dichlorophenyl, MRS7788 <b>18</b>, and 2-heptan-4-yl-<i>N</i>-4-iodophenyl, MRS8054 <b>39</b>, derivatives were orally bioavailable in rat. 2-Heptan-4-yl-<i>N</i>-3,4-dichlorophenyl <b>14</b> and 2-cyclononyl-<i>N</i>-3,4-dichlorophenyl <b>20</b> derivatives and <b>39</b> greatly enhanced Cl-IB-MECA-stimulated [³⁵S]GTPγS binding <i>E</i>_max, with only <b>12b</b> trending toward decreasing the agonist EC₅₀. A feasible route for radio-iodination at the <i>p-</i>position of a 4-phenylamino substituent suggests a potential radioligand for allosteric site binding. …”

<i>Ssdp</i> knockdown and overexpression cause autism-like behavioral deficits in <i>Drosophila</i>. by Safa Salim (9186786)

Tubulin modifications and gamma-tubulin distribution in the tegument. by Inés Guarnaschelli (18102211)

Phase 1 study to evaluate the effects of rifampin or itraconazole on the pharmacokinetics of limertinib (ASK120067), a novel mutant-selective inhibitor of the epidermal growth fact... by Bei Cao (141848)

“…Coadministration of itraconazole increased the AUC_0-inf of limertinib by 289.8% (GLSM ratio, 389.8%; 90% CI, 334.07–454.82), but decreased that of CCB4580030 by 35.96% (GLSM ratio, 64.04%; 90% CI, 50.78–80.77).…”

Smoking impact on fibrosis and cancer gene expression. by Lorise C. Gahring (271630)

“…Even at this low magnification the increased dysplasia of the bronchial lining is visible (asterisks). Bar = 50 microns. B. Plots show the relative expression of selected pro-fibrotic genes in the α7^G or the α7^E260A:G and the relative impact of either LPS (from [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0187773#pone.0187773.ref007" target="_blank">7</a>]) or CS (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0187773#pone.0187773.t002" target="_blank">Table 2</a>). …”

Changes to distal lung structure of both α7 genotypes with and without CS exposure. by Lorise C. Gahring (271630)

“…In these representative sections the arrows point to AMs and in the α7^E260A:G arrow heads identify regions of increased cellularity that produce alveolar sacs of decreased size. …”

Expression levels of <i>Alox15</i>, <i>Hmox1</i> and <i>Fth1</i> in pulmonary myeloid cell populations. by Emilie Pollenus (10147748)

S1 Data - by Xiaoguang Zhang (1397257)

Table_1_Proteomic Analysis Reveals a Predominant NFE2L2 (NRF2) Signature in Canonical Pathway and Upstream Regulator Analysis of Leishmania-Infected Macrophages.xlsx by Juliana Perrone Bezerra de Menezes (6892616)

“…NRF2 signatures were present in both CPs and UTFs pathways. …”

Scores of each variable in the main components. by Leila Vahdatiraad (17382718)

“…Stellate sturgeon (<i>Acipenser stellatus</i>) fry, was exposed to diazinon (25, 50, and 75% of 96h-LC₅₀) for 6 days after pre-treatment with an HSP inducer (HSPi), TEX-OE^® (a prickly pear cactus extract), for 4 hours. …”

Schematic presentation of different GTRN motifs. by Alok Kumar Maity (2212204)

Effect of irradiation on GFAP immunostaining in mouse astroglia cells. by Nikolett Sándor (659792)

Effect of irradiation on claudin-5 immunostaining in mouse brain endothelial cells. by Nikolett Sándor (659792)