Laccase-catalyzed iodination of different mono-methoxy-substituted phenolic compounds (structures: see Figure 2). by Julian Ihssen (417694)

“…a<p>Reaction conditions: 4 mM educt, 50 mM potassium iodide, 100 µM ABTS and 0.25 mg mL⁻¹<i>T. versicolor</i> laccase, % conversion was calculated as the relative decrease in educt peak area compared to enzyme-free control reactions.…”

Assessment of vascular density with CD31 labeling. by Deepa Sharma (278210)

“…Scale bar: 50 μm. (B) Quantification of vascularity from whole tumour sections measured from high magnification microscopy indicates a decrease in vascularity with combined treatment (570 kPa, 40 min) when compared with heat alone 0 kPa, 40 min (n = 3–5). …”

Effect of miR155 on the expression of target genes. by Cui Lei (110562)

“…Treating miR155-overexpressing cells with EGF resulted in a further decrease of SMAD2. No significant changes in TCF4 or CMYC mRNA were observed between EGF-treated and miR155 mimic-transfected cells. …”

Normal occlusion in maturational life process by Daniela GARIB (12682165)

“…Objective: In this article, the occlusal and facial aging changes occurred during almost 50 years of follow-up are described. A normal occlusion sample from Bauru Dental School, University of São Paulo, Brazil, was evaluated at 13 (T1), 17 (T2) and 60 (T3) years of age. …”

Medication-overuse headache. Retrospective comparison of preventive treatments by Abouch V. Krymchantowski (5187023)

“…Sudden withdrawal and pharmacological prevention with one or more drugs were carried out. Adherence and the decrease of headache frequency of more than 50% were compared after four months between the one or two, three, and four drug groups. …”

Live-cell imaging of cAMP in Flamindo2/nlsFlamindo2-expressing COS7 cells. by Haruki Odaka (575909)

“…<p>(A) Representative images showing changes in fluorescence intensity (FI) by 50 µM forskolin application in Flamindo2-expressing COS7 cells. …”

Table_1_Angiotensin-I-converting enzyme inhibitory peptides from eel (Anguilla japonica) bone collagen: preparation, identification, molecular docking, and protective function on H... by Huan Xiang (460100)

“…</p>Results<p>Eel (Anguilla japonica) bone collagen was hydrolyzed by alcalase and the hydrolysate was separated into three fractions, among which the F2 displayed a higher level of ACE inhibitory activity. …”

Geographic distribution of random forest model predictions of Spotted and Eastern towhee species identity. by Ximena León Du’Mottuchi (21560805)

“…<b>(B)</b> The same results from <b>(A)</b> are plotted based on the percent of trees in the random forest classifier that supported the correct species identification; when less than 50% of trees supported the correct identification, the classifier made an incorrect species prediction. …”

The importance of the adaptive threshold. by Jorge F. Mejias (228294)

Data_Sheet_1_Hypoxia signaling in the equine small intestine: Expression and distribution of hypoxia inducible factors during experimental ischemia.PDF by Nicole Verhaar (8781686)

“…Additionally, mucosal HIF1α protein levels were determined by an Enzyme Linked Immunosorbent Assay (ELISA), and mRNA levels of HIF1α and its target genes by a two-step real-time Reverse Transcriptase Polymerase Chain Reaction. …”

Data_Sheet_1_A Comparative Analysis of Reactive Müller Glia Gene Expression After Light Damage and microRNA-Depleted Müller Glia—Focus on microRNAs.pdf by Seoyoung Kang (10033280)

“…Taken together, results show there is an overlap of gene regulatory events that occur in reactive MG after light damage (direct damage of neurons) and miRNA-depleted MG (Dicer-cKO), two very different paradigms. This suggests that MG miRNAs play an important role in a ubiquitous MG stress response and manipulating these miRNAs could be a first step to attenuate gliosis.…”

Autophagy core protein ATG5 is required for elongating spermatid development, sperm individualization and normal fertility in male mice by Qian Huang (127640)

“…In <i>Atg5^flox/flox; Stra8− iCre</i> mutant mice, testicular expression of the autophagosome marker LC3A/B-II was significantly reduced, and expression of autophagy receptor SQSTM1/p62 was significantly increased, indicating a decrease in testicular autophagy activity. …”

Data_Sheet_1_A Comparative Analysis of Reactive Müller Glia Gene Expression After Light Damage and microRNA-Depleted Müller Glia—Focus on microRNAs.pdf by Seoyoung Kang (10033280)

“…Taken together, results show there is an overlap of gene regulatory events that occur in reactive MG after light damage (direct damage of neurons) and miRNA-depleted MG (Dicer-cKO), two very different paradigms. This suggests that MG miRNAs play an important role in a ubiquitous MG stress response and manipulating these miRNAs could be a first step to attenuate gliosis.…”

Time-resolved UV-visible spectroscopy of bodipy-based materials by F Cucinotta (7836197)

“…The first set of materials is characterised by green luminescence that, as the dye loading increases from 1% to 50%, shows a decrease in quantum yields from 0.22 to 0.05 and a reduction of the excited state lifetime. …”

Igf signaling is required for cardiomyocyte proliferation during zebrafish heart development. by Ying Huang (53474)

“…E. A significant decrease (***<i>p</i><0.0001) in cardiomyocyte proliferation was detected in embryos treated with NVP-AEW541.…”

Synthesis and bioactivity of the γ-secretase modulator photo-probe AR243. by Thorsten Jumpertz (188948)

“…AR243 caused a dose-dependent decrease in Aβ42 levels with a concomitant increase in Aβ38 levels, confirming its bioactivity as a potent GSM with an IC₅₀ for Aβ42 reduction of 290 nM.…”

General effects of training. by Marieke van der Linden (268336)

BBR increases autophagic activity in cultured cells. by Wenxiao Jiang (777255)

“…<p><b>(A)</b> Western blotting of LC3B in HEK293 cells transfected with or without Htt and treated with BBR (0, 5, 25, 50, or 100 μM). …”

The attenuating effects of Msi1 knockdown on Hh signaling in MSC proliferation and apoptosis. by In-Sun Hong (284033)

“…Purmorphamine increased cell proliferation (<b>A</b>) and decreased TUNEL-positive cell numbers (<b>B</b>), while the 50 nM Msi1 siRNA transfection produced the opposite effects. …”

The β2AR Pathway Involves PI3K/AKT in Controlling Keratinocyte Migration by Raja K Sivamani (587219)

“…Error bars represent standard error of the mean, <i>n =</i> 4; <i>* p <</i> 0.05.</p> <p>(B) Keratinocyte migration was measured after exposure to either procaterol (10 nM), ICI-118,551 (20 μM, specific β2AR antagonist), procaterol with ICI-118,551, LY294002 (50 μM, PI3K inhibitor), or LY294002 (50 μM) with ICI-118,551 (20 μM). …”