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step decrease » sizes decrease (Expand Search), we decrease (Expand Search)
teer decrease » greater decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
2 step » _ step (Expand Search), a step (Expand Search)
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18781
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18782
Sensitivity analysis.
Published 2025“…For each patient, a constant 50% reduction in each activation mechanism was simulated and the mean reduction in IL6 peak was calculated (reference scenario, black dots, same values as shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1012908#pcbi.1012908.g008" target="_blank">Fig 8A</a> fourth panel); this analysis was then repeated by increasing ( + ) and decreasing (–) each parameter in 50% increments.…”
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18783
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18784
Supplementary Figures S1-S11 from The Novel, Small-Molecule DNA Methylation Inhibitor SGI-110 as an Ovarian Cancer Chemosensitizer
Published 2023“…Comparison of cell growth rates of parental A2780 cells (A), A2780-CDDP resistant cells (B), and CP70 CDDP resistant cells (C) treated with 5μM 5-aza-dC, or vehicle (DMSO 1:2000) for 48 hours followed by CDDP ranging from 0-50μM CDDP. …”
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18785
DataSheet1_Effects of pharmacogenomics-guided treatment on medication adherence and the antidepressant switching rate in major depressive disorder.docx
Published 2024“…Background<p>In the treatment of depression, medication plays a crucial role. However, insufficient patient adherence to medication often results in unsatisfactory treatment outcomes, increasing both the recurrence and rehospitalization rates of depression, and consequently imposing a greater economic burden on the healthcare system.…”
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18786
Coarse-grained model leads to collective behavior.
Published 2017“…The peak in susceptibility becomes higher the larger the number of cells, and NN distances decrease accordingly. Profiles in the inset were smoothed with a moving average filter spanning ten points. …”
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18787
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18788
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18789
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18790
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18791
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18792
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18793
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18794
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18795
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18796
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18797
Data_Sheet_1_SWL-1 Reverses Fluconazole Resistance in Candida albicans by Regulating the Glycolytic Pathway.doc
Published 2020“…In this study, we show that SWL-1 reverses resistance to fluconazole in C. albicans when delivered in combination, with a sharp decrease in the IC<sub>50</sub> of fluconazole from >200 to 3.74 ± 0.25 μg/ml, and also reverses the fluconazole resistance of C. albicans in vitro, with IC<sub>50</sub> from >200 to 5.3 ± 0.3 μg/ml. …”
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18798
An Integrated Disease/Pharmacokinetic/Pharmacodynamic Model Suggests Improved Interleukin-21 Regimens Validated Prospectively for Mouse Solid Cancers
Published 2011“…Simulations of the verified model surfaced important therapeutic insights: (1) Fractionating the standard daily regimen (50 µg/dose) into a twice daily schedule (25 µg/dose) is advantageous, yielding a significantly lower tumor mass (45% decrease); (2) A low-dose (12 µg/day) regimen exerts a response similar to that obtained under the 50 µg/day treatment, suggestive of an equally efficacious dose with potentially reduced toxicity. …”
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18799
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18800