LPC-DHA inhibits Srebp activity and de novo lipogenesis and Mfsd2a is regulated by Srebp. by Jia Pei Chan (5593388)

“…<p>(A) Western blot analysis of Scd1 and Mfsd2a expression in NSC^WT and NSC^KO treated with or without 50μM LPC-DHA. …”

Attenuation of Quorum Sensing Regulated Virulence of <i>Pectobacterium carotovorum</i> subsp. <i>carotovorum</i> through an AHL Lactonase Produced by <i>Lysinibacillus</i> sp. Gs50 by Sneha S. Garge (3375242)

“…Our results demonstrate the potential of <i>Lysinibacillus</i> sp. Gs50 as a preventive and curative biocontrol agent.…”

Preliminary dose-response experiments. by Noelia Torremadé (3687523)

Effect of the seal resistance on circuit parameters. by Matej Hoťka (4610938)

“…<i>Right panel</i>: Simulated experiment with two events. The first event contained a step decrease of <i>R</i>_<i>Seal</i> from 100 to 10 GΩ while the second event contained a step change of <i>C</i>_<i>M</i> from 98.7 fF to 99.0 fF. …”

Membrane-localized AR facilitates productive endocytosis and nuclear trafficking of KSHV. by Xing Wang (154377)

“…Cells were performed as mentioned above, except lacking of Triton X-100 treatment in non-permeabilized group. Scale bars represent 50 μm. (c) Knockdown of AR and EphA2 expression reduces KSHV endocytosis, as indicated by decreasing gB staining in cells. …”

Minimal dataset. by Jennifer M. Kwan (3350321)

“…</p><p>Methods</p><p>We conducted a single center retrospective cohort study including 2165 cancer patients treated with ICIs between 2013 and 2020. …”

Role of the ACB domain and linker region in NMT2 activity. by Eric Soupene (64584)

“…Human NMT2 enzyme was added at a concentration of 50nM in the presence of 5μM C₁₄-CoA. …”

Defects in the conduction of somatosensory evoked potentials of median and tibial nerves in a healthy child and in H-ABC patient. by Jose R. Eguibar (8563227)

microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration - Fig 6 by Surjyadipta Bhattacharjee (3181674)

“…After vacuum evaporation of HFIP, aliquoted peptide was re-suspended with DMSO to 5 mM and diluted to 5 μM into the cell culture media; <b>(B)</b> cells were treated with a scrambled miRNA-34a sequence (miRNA-34a-<b>sc</b>; 30 nM;, control, <b>a-d</b>, middle row); or <b>(C)</b> with an LNA-stabilized miRNA-34a (30 nM; miRNA-34a stressed; <b>a-d</b>; bottom row); treatments were for 24 hr before incubation with 5 uM of Aβ42 (made up as in [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref033" target="_blank">33</a>]) for another 24 hr before assay; MG cells were subsequently stained using a murine amyloid beta MABN10 (red fluorescence λ_max~650 nm; anti-Aβ antibody, clone W0-2; Millipore, Bellerica MA), a TREM-2 antibody (M-227): sc-48765 (green fluorescence; λ_max~510 nm; Santa Cruz, Santa Cruz CA) or DAPI nuclear stain (blue fluorescence; λ_max~470 nm) as in <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.g003" target="_blank">Fig 3</a>;</b> arrows indicate Aβ42 uptake into MG cells; note decreased presence of TREM2 in miRNA-34a treated MG cells (bottom row, panel B) and decrease in ingested Aβ42 peptide within C8B4 cells (<b>C</b>; bottom row, panel <b>d</b>). …”

High-dose thiamine prevents brain lesions and prolongs survival of <i>Slc19a3</i>-deficient mice by Kaoru Suzuki (4217638)

“…To investigate the molecular mechanisms of neurodegeneration in SLC19A3 deficiency and whether administration of high-dose thiamine prevents neurodegeneration, we generated homozygous Slc19a3 E314Q knock-in (KI) mice harboring the mutation corresponding to the human SLC19A3 E320Q, which is associated with the severe form of THMD2. …”

Simulated average monthly flow at the 10 outflow assessment nodes in the five river basins over the 2008 to 2020 period (HMRB: Harirod-Murghab River Basin, HRB: Helmand River Basin... by Fazlul Karim (7225826)

Theoretical Studies on the Mechanism, Enantioselectivity, and Axial Ligand Effect of a Ru(salen)-Catalyzed Asymmetric Cyclopropanation Reaction by Ting Shi (3955)

“…Five proposed reaction pathways, including (1) a stepwise process containing the formation of carbene species and cyclopropanation step (path a), (2) a one-step process (path b), (3) a bis-carbene mechanism (path c), (4) a three-centered-intermediate pathway (path d), and (5) the main side reaction of dimerization of EDA (path e), are taken into consideration to determine the most favorable mechanism. …”

SEM images of lattice scaffolds; A) 4 layers, B) 6 layers, C) 8 layers, D) 10 layers, and staggered scaffolds; E) 4 layers, F) 6 layers, G) 8 layers, H) 10 layers. by Zahra Yazdanpanah (10038944)

Position of committed effective dose <i>E</i>_U+LS between <i>E</i>_LS and <i>E</i>_U (Bq d^–1). by Martin Šefl (11607984)

A complete set of mathematical model equations utilized in ILYCM software to develop S. <i>frugiperda</i> phenology for each life stage. by Marian Adan (16641634)

Example response to perturbation from a single participant. by Eric R. Walker (5774600)

“…<p>COM Sway and step width from a destabilizing perturbation (5%BW no hold) and stabilizing perturbation (2.5%BW no hold) trial. …”

Fig 2 - by Muhammad Imran Nisar (10226212)

Individual serotype carriage rates over the study period. by Muhammad Imran Nisar (10226212)

The carriage rate of VT serotypes by number of doses of vaccine. by Muhammad Imran Nisar (10226212)

Serotype specific carriage rate from 2014–18 in Matiari, Pakistan. by Muhammad Imran Nisar (10226212)