Identification of Potent DNA Gyrase Inhibitors Active against Mycobacterium tuberculosis by Bongkochawan Pakamwong (12315428)

“…Models of complexes of compounds <b>G24</b> and <b>G26</b> bound to the M. tuberculosis DNA gyrase ATP-binding site, generated by molecular dynamics simulations followed by pharmacophore mapping analysis, showed hydrophobic interactions of inhibitor hydrophobic headgroups and electrostatic and hydrogen bond interactions of the polar tails, which are likely to be important for their inhibition. Decreasing compound lipophilicity by increasing the polarity of these tails then presents a likely route to improving the solubility and activity. …”

Apoptosis is induced in EYFP-LIPT2 and ΔmitotagLIPT2 expressing cells. by Emanuele Bernardinelli (4117372)

Expression of <i>pax7</i> genes increases during white muscle regeneration in trout. by Cécile Rallière (86527)

Fig 3 - by Masaru Sakai (1669627)

Immunoblot images of α-SMA, PCNA and Sirt1. by Hanhan Liu (568151)

Jag2 knockdown ameliorates mitochondrial dysfunction induced by hypoxia. by Hanhan Liu (568151)

Mutation prevalence of <i>podhfr</i>, <i>pocrt</i> and <i>pocytb</i> in <i>P</i>. <i>ovale curtisi</i> and <i>P</i>. <i>ovale wallikeri</i> isolates. by Jing Chen (4762)

Jag2 deficiency prevents proliferation and promotes apoptosis in hypoxia-treated PASMCs. by Hanhan Liu (568151)

The expected heterozygosity <i>(H</i>_<i>e</i>) of microsatellite loci flanking <i>podhfr</i> gene in <i>P</i>. <i>ovale curtisi</i>. by Jing Chen (4762)

Jag2 regulates mitochondrial injury in hypoxia-induced PASMCs via Sirt1 signaling. by Hanhan Liu (568151)

Protein levels of Bcl-2 family markers in limbal stromal cells (LSCs) and in Aniridia-LSCs (AN-LSCs), after treatment with 0 µM, 50 µM and 75 µM Cobalt chloride (CoCl₂),... by Shanhe Liu (5251313)

LPC-DHA affects membrane phospholipid saturation. by Jia Pei Chan (5593388)

“…<p>Targeted lipidomic analysis of NSC^WT and NSC^KO cells treated with or without 50 μM LPC-DHA for 16 hours. (A) NSC^WT cells showed increased DHA in PC, PE, and PS relative to NSC^KO cells. …”

Global effects of RG108 on DNA modifications and DNMTs and TETs enzymatic activities in hBMSCs. by Rahyza I. F. Assis (6037928)

“…(A) Global methylation was assessed using Imprint Methylated DNA Quantification Kit showing a significant decrease in the RG108 group. …”

Lakes in Europe harbour more anthropogenic microparticles than elsewhere. by Andrew J. Tanentzap (10227764)

RNAi-based screen for genes that modify aSyn oligomerization in living cells. by Susana A. Gonçalves (199613)

“…</b> Representative live cell imaging pictures of aSyn-BiFC stable H4 cells silenced for hits that increase (<i>RAB8B</i>, <i>RAB11A</i>, <i>RAB13</i>, <i>RAB39B</i>, <i>CAMK1</i>, <i>DYRK2</i>) or decrease (<i>CC2D1A</i>, <i>CLK4</i>, <i>SYTL5)</i> aSyn oligomerization (green). …”

Intracellular pH of <i>C</i>. <i>albicans</i> ATCC 90028; FLC-susceptible <i>C</i>. <i>albicans</i> D27and FLC-resistant <i>C</i>. <i>albicans</i> D15.9 with and without the treatm... by Mohammad Irfan (464459)

Linear mixed model results: Effect of bar height and approach stride number on sagittal joint kinematics at take-off to a jump in agility dogs. by Leena Inkilä (20614460)

The inactivation of <i>Kdm6a</i> in mice had age- and gender-dependent effects on normal hematopoiesis. by Ling Tian (107492)

Cardiac Contractility Structure-Activity Relationship and Ligand-Receptor Interactions; the Discovery Of Unique and Novel Molecular Switches in Myosuppressin Signaling by Megan Leander (459603)

“…Further, these motifs were present in red flour beetle, common water flea, honey bee, domestic silkworm, and termite MS-Rs. RhpMS and DrmMS decreased <i>R</i>. <i>prolixus</i> cardiac contractility dose dependently with EC₅₀ values of 140 nM and 50 nM. …”

LV function and geometry: Exercise cohort. by Stephanie L. Samani (17896610)

“…Additionally, miR-22 and miR-30e decreased with exercise and mapped to a localized inflammatory process, the inflammasome (NLRP-3, whereby a 2-fold decrease in NLRP-3 mRNA occurred with exercise (p < 0.05).…”