DataSheet_1_Dectin-1 Controls TSLP-Induced Th2 Response by Regulating STAT3, STAT6, and p50-RelB Activities in Dendritic Cells.pdf by Chao Gu (402478)

“…Dectin-1 stimulation induced STAT3 activation and decreased the transcriptional activity of p50-RelB, both of which resulted in reduced OX40L expression on TSLP-activated mDCs. …”

Antioxidation and Anti-Inflammatory Activity of Prussian Blue Nanozymes to Alleviate Acetaminophen-Induced Acute Liver Injury by Qiang Feng (88137)

“…Furthermore, the therapeutic mechanism studies have shown that PB nanozymes with abundant and variable valence states could not only directly scavenge ROS but also through the Keap1-Nrf2/HO-1 pathway to reduce oxidative stress. Moreover, the decreased expression levels of myeloperoxidase and F4/80 in the liver, which are markers of neutrophil and macrophage infiltration, indicated that the Prussian blue nanozymes modulates inflammation to protect against APAP-induced acute liver injury. …”

Medium-Ring Keto Bislactams with Antischistosomal Activity by Rongguo Ren (2943366)

“…We discovered medium-ring keto bislactams as a new antischistosomal chemotype. …”

Western blots comparing losartan and water groups. by Harry A. Quigley (695817)

Adult social behavior to a conspecific. by Gordon A. Barr (11163243)

Photoreceptor cell death and protective effect of the blue-blocking filter on cone photoreceptors. by Javier Vicente-Tejedor (4966858)

Experimental design. by Xueyan Lin (448667)

“…The C and MNS group were gavaged with equal volume normal saline, the ML and MR group gavaged with lactulose at a dose of 10 mL/kg body weight and rifaximin at a dose of 50 mg/kg body weight respectively once a day for 8 weeks until the end of the experiment. …”

Histological evaluation of joints after oral administration of GLME to rats with MIA-induced OA. by JooYeon Jhun (3797404)

Cnot4 heterozygosity confers resistance to high fat diet-induced obesity. by Tomokazu Yamaguchi (8284989)

Effect of Safr and Cands on the gene expression level of monoamine oxidase (MAO-A, fold change) and (MAO-B, fold change) as well as the activities of monoamine oxidase (MAO, μM 4-H... by Nagwa Ibrahim Shehata (17319689)

The simplified molecular composition of PSD and lattice model of AMPA receptor diffusion. by Rahul Gupta (358711)

CD4 cell count at viral set-point and mean CD4 cell count at each time period. by Luuk Gras (370061)

Culicidae species frequency displayed as a cloud for each of three ED categories (low, moderate and high) in forest fringe collections in rural areas of Amazonian Brazil. by Leonardo Suveges Moreira Chaves (5554235)

Tornado diagram of the one-way sensitivity analyses. by Iris W. A. Boot (18823769)

Mutations on <i>ent</i>-kaurene oxidase 1 encoding gene attenuate its enzyme activity of catalyzing the reaction from <i>ent</i>-kaurene to <i>ent</i>-kaurenoic acid and lead to de... by Hui Zhang (7197)

“…Through re-sequencing on the mutant, wild-type and their F₂ populations, we identified two continuous mutated sites on <i>ent-kaurene oxidase 1</i> (<i>OsKO1</i>) gene, which result in the conversion from Thr to Met in the cytochrome P450 domain. …”

Discovery of Benzocycloalkane Derivatives Efficiently Blocking Bacterial Virulence for the Treatment of Methicillin-Resistant <i>S. aureus</i> (MRSA) Infections by Targeting Diapop... by Youxin Wang (153032)

“…In our previous work, diapophytoene desaturase (CrtN) was identified to be an attractive and drugable target for fighting pigmented <i>S. aureus</i> infections. In this research, we developed a series of effective benzocycloalkane-derived CrtN inhibitors with submicromolar IC₅₀. …”

Sensitivity of mean population biomass and cumulative harvest to initial biomass to the rate of demographic change due to climate impacts. by Jameal F. Samhouri (10136090)

“…All parameters are at their default values (<a href="/article/info:doi/10.1371/journal.pclm.0000624#pclm.0000624.s002" target="_blank">S1 Table</a>); note that initial and final values of <i>r</i> and <i>K</i> differ in the decreasing versus increasing scenarios (<a href="/article/info:doi/10.1371/journal.pclm.0000624#pclm.0000624.s003" target="_blank">S2 Table</a>). …”

Inhibition of IL-6 Signaling Pathway by Curcumin in Uterine Decidual Cells by Y. Sangeeta Devi (737137)

“…To further understand whether NF-ҡB is involved in this inhibition, we examined the effect of curcumin on the expression of p50 and p65 subunits of NF-ҡB in decidual cells. …”

Rank-Order stability with longer conversations. by Grgur Kovač (19484728)

The Reversal Effects of 3-Bromopyruvate on Multidrug Resistance <i>In Vitro</i> and <i>In Vivo</i> Derived from Human Breast MCF-7/ADR Cells by Long Wu (655081)

“…Multidrug resistance reversal by 3-Bromopyruvate occurred through at least three approaches, namely, a decrease in the intracellular level of ATP and HK-II bioactivity, the inhibition of ATPase activity, and the slight decrease in P-glycoprotein expression in MCF-7/ADR cells.…”