Effect of treatment with TSA on Aβ42 and Aβ40 levels in APPswe/PS1dE9 transgenic mice. by Li Shen (110858)

HlyA is responsible for UPEC persistence in the bladder. by Manisha Naskar (2613763)

Data_Sheet_1_The Modulatory Role of CYP3A4 in Dictamnine-Induced Hepatotoxicity.docx by Zhuo-Qing Li (4455073)

“…Contrarily, the cytotoxicity was decreased in CYP3A4-inhibited PHH and CYP3A4 OE HepG2 and L02 cells inhibited by ketoconazole (KTZ). …”

The number of amyloid plaques and amount of Aβ_1-42 were reduced in S100A9 KO/Tg mice. by Hee Jin Kim (469168)

“…Sections are 4 µm thick. ((a) – (h) Scale bar; 200 µm, (i)-(l) scale bar; 50 µm). …”

Characterization of journals being listed in the DOAJ and their development over time (2011–2018). by Georg Richtig (4582933)

Glycerol biosynthesis and CO₂ production. by Elham Aslankoohi (701337)

“…<p>Glycerol biosynthesis from dihydroxyacetone phosphate is a two-step process. The first step which is catalyzed by the Gpd enzyme, is rate limiting for the production of glycerol. …”

The conserved phenylalanine residue in PRMT5 is critical for inhibition by the five compounds. by Gui-Mei Kong (4353751)

“…D, The F225M mutation in PRMT5 decreased the IC₅₀ values of the compounds, as determined by quantitation and analysis of methylation assay results.…”

Antimicrobial activity of RP-1 peptide conjugate with ferrocene group by Natalia C. S. Costa (8626206)

“…In comparison with amphotericin B, a second-line drug approved for leishmaniasis treatment, (IC₅₀ = 0.63 μmol L^-1), Fc-RP1 was more active and showed a 2.5-fold higher selectivity index. …”

Characterization of journals being listed on Beall’s list and their development over time (2011–2018). by Georg Richtig (4582933)

ING1 is one of the miR-371-5p targets and negatively regulated by miR-371-5p. by De He (497662)

Fig 4 - by Sonia Borao (18764889)

“…Line plots represent the average splicing efficiency in <i>Δsaf5</i> (red line) and wild type (blue line) strains. Genes with a decrease of 50% in splicing efficiency in <i>Δsaf5</i> compared with wild type strain in the first (left panel), second (middle panel) and third (right panel) intron are represented.…”

Discovery, Synthesis, and Activity Evaluation of Novel Five-Membered Sulfur-Containing Heterocyclic Nucleosides as Potential Anticancer Agents In Vitro and In Vivo by Er-Jun Hao (10097665)

“…Among them, compound <b>22o</b> exhibited remarkable antiproliferative activity against HeLa cells and was more potent than cisplatin (IC₅₀ = 2.80 vs 7.99 μM). Furthermore, mechanism studies indicated that <b>22o</b> inhibited cell metastasis, induced cell apoptosis, decreased mitochondrial membrane potential, and activated autophagy through the PI3K-Akt-mTOR signaling pathway. …”

Discovery, Synthesis, and Activity Evaluation of Novel Five-Membered Sulfur-Containing Heterocyclic Nucleosides as Potential Anticancer Agents In Vitro and In Vivo by Er-Jun Hao (10097665)

“…Among them, compound <b>22o</b> exhibited remarkable antiproliferative activity against HeLa cells and was more potent than cisplatin (IC₅₀ = 2.80 vs 7.99 μM). Furthermore, mechanism studies indicated that <b>22o</b> inhibited cell metastasis, induced cell apoptosis, decreased mitochondrial membrane potential, and activated autophagy through the PI3K-Akt-mTOR signaling pathway. …”

Correlation between total memory or naïve Tregs with PD1⁺ CD95⁺ cells. by Vedran Brezar (337452)

A Randomized Clinical Trial to Evaluate Two Doses of an Intra-Articular Injection of LMWF-5A in Adults with Pain Due to Osteoarthritis of the Knee by David Bar-Or (518741)

HIV-specific CD4⁺ T-cell responses were amplified by IL-2 treatment and inversely correlate with VL after treatment interruption. by Vedran Brezar (337452)

Table1_Effectiveness of dapagliflozin as an insulin adjunct in type 1 diabetes: a semi-mechanistic exposure-response model.DOC by Victor Sokolov (14181554)

“…Even so, this association remained flat, with a 50% decrease in the basal insulin dose from pretreatment level, resulting in ∼5% increase in glucose exposure. …”

DataSheet1_Macleayins A From Macleaya Promotes Cell Apoptosis Through Wnt/β-Catenin Signaling Pathway and Inhibits Proliferation, Migration, and Invasion in Cervical Cancer HeLa Ce... by Chunmei Sai (11240097)

“…The Wnt/β-catenin signaling cascade activation was verified using the Dual-Glo® Luciferase assay. We found that MA inhibited the growth of HeLa cells at 72 h (IC₅₀ = 26.88 µM) via inducing apoptotic process, reduced the proliferation rate by 29.89%, and decreased the cells migration and invasion as compared to the untreated group. …”

(A) Mortality by Wangsen Cao (49354)

Image_2_Thy-1 (CD90)-Induced Metastatic Cancer Cell Migration and Invasion Are β3 Integrin-Dependent and Involve a Ca2+/P2X7 Receptor Signaling Axis.TIF by Marianne Brenet (2194243)

“…In addition, cell migration and invasion were precluded when the P2X7 receptor was pharmacologically blocked. Moreover, the ability of breast cancer and melanoma cells to transmigrate through an activated endothelial monolayer was significantly decreased when the β₃ Integrin was silenced in these cancer cells. …”