A custom built widefield microscope. by Dinu F. Albeanu (58044)

“…The ordering of parts is as follows: CCD camera, an F to C mount adapter with an emission filter placed inside or on top of the coupler, a 62 mm, 105 mm FL lens, a 62 mm to 52 mm step down ring, a 52 mm to 52 mm coupling ring, and a 52 mm, 50 mm FL lens. …”

A- and D‑Ring Structural Modifications of an Androsterone Derivative Inhibiting 17β-Hydroxysteroid Dehydrogenase Type 3: Chemical Synthesis and Structure–Activity Relationships... by Francisco Cortés-Benítez (4523380)

“…Decreasing the intratumoral androgen biosynthesis by using an inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) is a strategy to treat prostate cancer. …”

Stochastic property of the two-state bacterial receptor model with the multiple methylation sites. by Masatoshi Nishikawa (363723)

“…The activity as the number of active chemoreceptors (red) is plotted as a function of time. For step increase and decrease in chemoattractant concentration (blue), the activity shows response and adaptation. …”

Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2. by P, Sneha

“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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DataSheet_1_Pathological diagnostic nomograms for predicting malignant histology and unfavorable pathology in patients with endophytic renal tumor.docx by Xinxi Deng (13835602)

“…In addition, if demographic characteristics and laboratory tests were excluded from the nomograms, only the components of the R.E.N.A.L. Nephrometry Score system were included to predict MH and UP, the AUC decreased to 0.781 and 0.660, respectively (P=0.001 and 0.013, respectively).…”

Table1_In Vivo Characterization of a Red Light-Activated Vasodilation: A Photobiomodulation Study.DOCX by Agnes Keszler (12486448)

“…The vasodilatory nitric oxide precursor was analyzed in plasma and muscle with triiodide-dependent chemiluminescence. First, a 5–10 min irradiation of a 3 cm² area in the hind limb at 670 nm (50 mW/cm²) produced optimal vasodilation. …”

Image1_In Vivo Characterization of a Red Light-Activated Vasodilation: A Photobiomodulation Study.TIF by Agnes Keszler (12486448)

“…The vasodilatory nitric oxide precursor was analyzed in plasma and muscle with triiodide-dependent chemiluminescence. First, a 5–10 min irradiation of a 3 cm² area in the hind limb at 670 nm (50 mW/cm²) produced optimal vasodilation. …”

Short-pulse photostimulation of VGluT2 GRN neurons in the freely walking mouse. by Maxime Lemieux (6630917)

“…(C) Averaged rectified EMG response of the iTA for each of the 5 periods of the step cycle. Upward arrows indicate a motor increase, and downward arrows indicate a motor decrease. …”

Knock-down of <i>PYCR</i> genes effect is independent of proline and nucleotide biosynthesis. by Saif Sattar Alaqbi (12055053)

Table_2_Prognostic and Clinicopathological Significance of Long Non-coding RNA PANDAR Expression in Cancer Patients: A Meta-Analysis.DOCX by Lizhi Han (8068790)

“…However, high or low expression of PANDAR did not differ in the prediction of event-free survival (EFS). Moreover, we discovered that high PANDAR expression was closely related to decreased OS in colorectal cancer (pooled HR 3.43, 95%CI 2.06–5.72) and reduced expression level of PANDAR was markedly related to poor OS (pooled HR 0.65, 95%CI 0.45–0.88) in non-small cell lung cancer. …”

Table_1_Prognostic and Clinicopathological Significance of Long Non-coding RNA PANDAR Expression in Cancer Patients: A Meta-Analysis.DOCX by Lizhi Han (8068790)

“…However, high or low expression of PANDAR did not differ in the prediction of event-free survival (EFS). Moreover, we discovered that high PANDAR expression was closely related to decreased OS in colorectal cancer (pooled HR 3.43, 95%CI 2.06–5.72) and reduced expression level of PANDAR was markedly related to poor OS (pooled HR 0.65, 95%CI 0.45–0.88) in non-small cell lung cancer. …”

Fig 7 - by Tong Zhuang (17847113)

The working model of blood pressure regulation by Csk and Angiotensin II through Src. by Hyeon-Ju Lee (796527)

Monobenzyltin Complex C1 Induces Apoptosis in MCF-7 Breast Cancer Cells through the Intrinsic Signaling Pathway and through the Targeting of MCF-7-Derived Breast Cancer Stem Cells... by Somayeh Fani (2967933)

“…<p><b>(A, B) Aldefluor assay of MCF-7 cancer stem cells, (C) western blot analysis of protein markers of the Wnt/β-catenin self-renewal pathway in MCF-7 treated cells with a concentration of 2.5 μg/mL (IC</b>_<b>50</b><b>).…”

Characterization of the Thermally Induced Topochemical Solid-State Transformation of NH₄[N(CN)₂] into NCNC(NH₂)₂ by Means of X-ray and... by Bettina V. Lotsch (1467520)

“…The mechanism of the solid−solid transformation of NH₄[N(CN)₂] into NCNC(NH₂)₂, which represents the isolobal analogue of Wöhler's historic conversion of ammonium cyanate into urea, has been investigated by temperature-dependent single-crystal and powder X-ray diffraction, neutron powder diffraction, and Raman and solid-state NMR spectroscopy as well as thermoanalytical measurements. …”

Characterization of the Thermally Induced Topochemical Solid-State Transformation of NH₄[N(CN)₂] into NCNC(NH₂)₂ by Means of X-ray and... by Bettina V. Lotsch (1467520)

“…The mechanism of the solid−solid transformation of NH₄[N(CN)₂] into NCNC(NH₂)₂, which represents the isolobal analogue of Wöhler's historic conversion of ammonium cyanate into urea, has been investigated by temperature-dependent single-crystal and powder X-ray diffraction, neutron powder diffraction, and Raman and solid-state NMR spectroscopy as well as thermoanalytical measurements. …”

Dietary fatty acids fine-tune Piezo1 mechanical response by Luis O. Romero (6326268)

“…Stacked bar chart illustrating the membrane fatty acid distribution in N2A cells and HMVEC, as determined by LC-MS. Bars are mean ± SD. n is denoted above the x-axis. …”

Bacterial amyloid curli acts as a carrier for DNA to elicit an autoimmune response via TLR2 and TLR9 by Sarah A. Tursi (3927317)

“…Here, we show that DNA complexed with amyloid curli powerfully stimulates Toll-like receptor 9 (TLR9) through a two-step mechanism. First, the cross beta-sheet structure of curli is bound by cell-surface Toll-like receptor 2 (TLR2), enabling internalization of the complex into endosomes. …”

A novel index based on planktonic copepod reproductive traits as a tool for marine ecotoxicology studies by Mohamed Bakr, Hussain

“…At high concentrations, cadmium and silver induce an increase in EPR in the copepods Acartia tonsa and Acartia hudsonica, while exposure to mercury decreases EPR in adults by 50%. All three metals affect HS, with mercury inducing a stronger effect than cadmium and silver. …”
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IGF-1 induces an increase in <i>PRNP</i> expression through the PI3K-Akt-FOXO3a pathway. by Ting Liu (45625)

“…No notable changes were detected after 1 hour of treatment, but the <i>PRNP</i> mRNA level gradually decreased over time, and an approximately 50% decrease was observed after 24 hours of treatment. …”